Departments

We offer coordinated, multidisciplinary clinical care for people with rheumatoid and other types of inflammatory arthritis, as well as osteoarthritis and a variety of autoimmune diseases, including lupus, scleroderma, myositis, and vasculitis. Our physicians are experts at diagnosing and treating more than 200 types of rheumatologic disorders, some of which are difficult to pinpoint. Rheumatic disorders affect the joints, muscles, and bones and often include autoimmune diseases that disrupt the body’s immune system by causing inflammation and breaking down connective tissue and related body structures. We work closely with other specialists at Yale including pulmonologists, nephrologists, gastroenterologists, cardiologists, allergists, neurologists, dermatologists, surgeons, and orthopaedists to care for complex rheumatic and autoimmune diseases. Specialized care is offered in the following areas: Antiphospholipid antibody syndrome Rheumatoid arthritis and other types of inflammatory arthritis Scleroderma and myositis Systemic lupus erythematosus Transition program for young adults Vasculitis State-of-the-art infusion sites at Yale New Haven Hospital and in the Yale New Haven Health Interventional Immunology Center in North Haven Full array of imaging and laboratory services Nationally recognized clinical research programs that are integrated with clinical care to offer the most advanced treatments to patients with arthritis and autoimmune diseases

Covering every aspect of health care for adults, Internal Medicine is the largest department in the Yale School of Medicine, and the largest clinical service at Yale New Haven Hospital. We provide comprehensive and specialized services in all areas in a variety of outpatient settings as well as the Veterans Affairs (VA) Connecticut Health Care System campus in West Haven. Our culture of collaboration and research gives patients access to expert opinions from nearly 1,000 doctors, as well as opportunities to get tomorrow’s health care today through more than 100 clinical trials. Most importantly, we attend to our diverse community of patients with compassionate, thorough care. Specialized care is offered in the following areas: Allergy & clinical immunology Cardiovascular medicine Digestive diseases Endocrinology General internal medicine Geriatrics Hematology Infectious diseases Medical oncology Occupational health & environmental medicine Nephrology Pulmonology, critical care & sleep medicine Rheumatology International reputation for work in understanding function, independence, and quality of life in older persons Key research breakthroughs of the past decade that include the development of a protective Lyme bacillus disease vaccine, exploration of the underlying causes of allergic disease, and the discovery of novel inherited immunological diseases Largest interventional cardiology program in Connecticut Major referral center for patients with type 1 and type 2 diabetes, as well as other metabolic conditions Nationally ranked program in kidney diseases and the largest kidney transplant program in New England, with multidisciplinary care clinics One of the largest peripheral vascular programs in the country, with leadership and participation in multiple new percutaneous device trials Once of only a few motility centers in Connecticut to provide all motility procedures and services Unique medical forensic exams for individuals with claims of torture who are seeking asylum in the U.S.

If a child is complaining of pain in the joints, muscles, bones, or tendons—or exhibits other symptoms of arthritis—a pediatrician might recommend seeing a pediatric rheumatologist. We have the expertise to care for a child’s specific needs when it comes to autoimmune and rheumatologic disorders and related conditions.

Our uncompromising faculty and staff are dedicated to the welfare of children and adolescents. One of two major pediatric centers in Connecticut, Yale offers an extensive range of services for patients through our 14 specialties. In addition, we have several interdisciplinary centers and programs that involve collaborations with multiple departments throughout Yale Medicine and Yale New Haven Children’s Hospital. Thanks to our reputation for comprehensive pediatric care, we serve as a regional and national center for referral and consultation. Many of our physicians are internationally recognized for their innovative approaches to the diagnosis and treatment of conditions including arrhythmias, diabetes, cystic fibrosis, childhood cancers, juvenile diabetes, dyslexia, blood disorders, infectious diseases, and complications of premature birth, as well as many other disorders. We are leaders in the global pediatric community, advocates for childhood health and development, and innovators in research. We rank among the top pediatric centers in the country with respect to National Institutes of Health support for research. Neonatal and pediatric ICUs that serve our most vulnerable patients with the highest level of care 24/7 subspecialty telephone consultation service for primary care clinicians with expected response time of three minutes More than 20 years of experience with neonatal and pediatric Extracorporeal Membrane Oxygenation, a sophisticated machine that acts as an artificial heart and lungs, crucial for some seriously ill infants One-call center that provides centralized appointment scheduling for all pediatric specialties Close collaboration with other Yale departments to provide such services as molecular and genetic diagnostic services, state-of-the art management of high-risk fetuses and newborns, bone marrow transplantation, and management of complex malignancies

We are committed to providing patient-focused, evidence-based care to all of our patients, pairing clinical expertise with the latest advances in technology. We offer a comprehensive range of imaging services, and tailor each exam to meet each patient’s specific needs. Our board-certified doctors are national and international leaders in diagnostic imaging and advanced image-guided therapies, and they are dedicated to maintaining the highest standards of care in patient safety, quality, and satisfaction. We employ a multidisciplinary approach to care, and collaborate with physicians from all medical specialties to make the most accurate diagnosis and determine the best treatment options. Yale patients have access to highly advanced imaging equipment, including an intraoperative MRI/IR/OR suite, and 3D tomosynthesis. Our radiologists conduct advanced research in MRI, MRS, PET, interventional oncology, and image processing. Specialized care is offered in the following areas: Abdominal imaging Breast imaging Cardiovascular imaging Emergency and trauma radiology Neuroradiology Nuclear medicine and molecular imaging (including PET/CT) Pediatric radiology Thoracic imaging Vascular/interventional radiology Rapid, in-house subspecialist imaging interpretations Overnight coverage by three in-house attending radiologists at Yale New Haven Hospital Leader in 3D tomosynthesis mammography imaging and research Leader in screening breast ultrasound Comprehensive multidisciplinary lung cancer screening program with ultra-low-dose CT scanning Cardiac CoreValue planning service, providing a minimally invasive transcatheter aortic valve implantation option for patients with severe aortic stenosis MRI for pacemaker patients Ultrasound contrast and elastography imaging Dedicated peripheral vascular ultrasound Integrated musculoskeletal ultrasound device Subspecialized pediatric interventional radiology expertise Recognized expertise in management of primary and secondary liver cancer Molecular imaging for recurrent prostate cancer and the diagnosis of Alzheimer’s disease Advanced tumor imaging for optimizing best treatment outcomes DaTscan, a diagnostic test for Parkinson’s Disease Portable neuro Intensive Care Unit (ICU) computed tomography (CT) scanning Interventional radiology with state-of-the-art minimally invasive image-guided therapy, including targeted and precision cancer treatments, back pain treatment, and biliary stone laser treatment, among others

Yale Cancer Center is Connecticut's only cancer center designated as a Comprehensive Cancer Center by the National Cancer Institute—and one of only 57 in the nation. The significance of this designation has profound implications for those who choose Smilow Cancer Hospital as the place where they will be cared for and receive treatment for their cancer. National Cancer Institute cancer centers are national leaders in cancer research, prevention, detection, and treatment. This provides patients at Smilow Cancer Hospital with novel treatment options and expert care.

The largest center for specialty dermatology in Connecticut, Yale’s Department of Dermatology is among the oldest in the United States. Our doctors and nurses provide safe, compassionate, and innovative care to all members of our community. We offer treatment for skin conditions, all of which can interfere with quality of life. Cutting-edge therapies are often the only hope for patients with resistant dermatologic illness, which affects the whole skin surface. Our physicians are deeply rooted in research, including the exploration of new technologies such as photopheresis for cutaneous T-cell lymphoma and graft-versus-host disease. Our patients often benefit from early access to new treatments and therapies discovered by researchers at Yale. Specialized clinics for organ transplant patients, photopheresis, ichthyosis, and inherited skin disease One of two centers in the state with a pigmented lesion clinic, phototherapy center, and cutaneous lymphoma clinic Cutting-edge microscopically controlled excision (Mohs technique) for recurrence of high-risk cancers Technically advanced referral center for expert diagnosis of benign and malignant skin disorders Large dermatopathology lab, which processes 75,000 patient biopsies annually

Yale’s Department of Obstetrics, Gynecology and Reproductive Sciences is dedicated to helping women at all stages of life. A global leader in women’s health, Yale is known for its innovative contributions to diagnosis and treatment, including: Developing the first fetal echocardiography Pioneering the first obstetrical ultrasound Developing the first fetal blood sampling and first fetal transfusion Offering the first chorionic villus sampling in New England Co-authoring the first U.S. study for first-trimester risk assessment Developing the first comprehensive first-trimester risk assessment program in New England Inventing fetal monitoring and many prenatal diagnostic and treatment techniques Our physicians tap into the broad expertise of our entire institution to provide compassionate, customized care for all of our patients, from adolescence through adulthood. Through eight subspecialty areas, we offer the most advanced diagnostics and therapies that harness the latest advances in technology. Recent clinical research includes a new emphasis on therapeutic vaccines in gynecologic oncology, novel treatments for endometriosis and menopause, a comprehensive patient safety program in maternal-fetal medicine, and an advanced fetal therapy program. Specialized care is offered in the following areas: Family planning Gynecologic oncology Gynecologic specialties Maternal-fetal medicine Obstetric specialties & midwifery Pediatric & adolescent gynecology Reproductive endocrinology & infertility Urogynecology & reconstructive pelvic surgery Maternal-fetal medicine service offers 24-hour on-site dedicated space for complex pregnancies and fetal care First in Connecticut to perform in-utero laser therapy in pregnancies complicated by twin-to-twin transfusion syndrome Outstanding survival outcomes for all types of gynecologic surgery, from open to robotic Pioneer in caring for patients with sexual intimacy issues after cancer surgery Fetal therapy program Midwifery and birthing center

Scleroderma (or systemic sclerosis) is a complex disease which results in chronic hardening and tightening of connective tissues, and patients can experience many different symptoms involving different organs. Our multidisciplinary team of doctors and nurses with expertise and an interest in scleroderma, including specialists in rheumatology, allergy and clinical immunology, pulmonary and critical care, cardiology, gastroenterology, nephrology, and dermatology, provide care for patients. The team provides coordinated, multidisciplinary, and compassionate care for patients and all the parts of the body scleroderma affects, including the skin, lung, heart, kidneys, and gastrointestinal system. We also address functional, nutritional, psychological, gynecological, urological, and/or sexual health challenges. The goal is improved quality of life for our patients. We strive to ease the burden on patients and their families. Support staff help patients gather outside medical records and coordinate appointments with different specialists at Yale so that patients can get all their relevant medical care in one place. Doctors readily communicate about the plan of care through the electronic health record. We also actively participate in clinical research, to bring the most innovative treatments for the disease to our patients. Yale has been designated as a Scleroderma Center by the Scleroderma Foundation.

The Body Imaging division at Yale consists of two cohesive sections (Abdominal Imaging and Ultrasound) whose faculty members provide world-class subspecialty clinical care across a wide range of diseases. Our commitment to clinical excellence, compassion for our patients, and reputation for progressive innovation has allowed us to remain on the forefront of clinical medicine. Equipped with cutting-edge technology, the section of Abdominal Imaging provides comprehensive Body MR, Body CT, and fluoroscopy imaging services that encompass a full range of diseases involving the abdomen and pelvis with a focus on high-end oncology imaging. The Ultrasound section offers a comprehensive range of imaging exams that encompass a wide-range of both vascular and non-vascular pathology. Our state-of-the-art equipment, coupled with our world-class facilities at both the Smilow Cancer Center and our various outpatient sites provide an unparalleled experience for all our patients.

An ultrasound is a high-frequency soundwave that can create images from inside the body. It is a commonly ordered diagnostic imaging tool used for screening and examining organs and tissues. It is often used to assist and guide doctors performing other medical procedures, such as biopsies. An ultrasound is painless and does not expose patients to any radiation. We specialize in both screening and diagnostic vascular ultrasound, including aortic aneurysm screening and follow-up post-aneurysm repair, evaluation of vascular access complications, arterial bypass graft surveillance, renal artery stenosis, venous thrombosis, and venous reflux.We also provide evaluation of dialysis fistulas and grafts, native peripheral arteries, and peripheral arterial disease. We have recently introduced two new ultrasound clinical applications that incorporate the latest advancements in technology: Elastography to assess liver fibrosis, and contrast-enhanced ultrasound of liver masses. Elastography to assess liver fibrosis This technique allows doctors to evaluate fibrosis in the liver while simultaneously assessing the liver with regular ultrasound to check for masses and other abnormalities. Noninvasive, image-guided elastography of the liver can accurately detect liver fibrosis, allowing patients with chronic liver disease to be safely monitored and avoid the risks associated with liver biopsy. We are also investigating elastography of lesions to determine if this technique can be used to differentiate between benign and malignant lesions. Contrast-enhanced ultrasound of liver masses The intravenous injection of microbubbles (tiny bubbles of gas), in combination with ultrasound, allows physicians to determine if a liver lesion is benign or malignant. This method can determine the risk of developing cancer or recurrence of a tumor in at-risk patients with cirrhosis, or those who have been treated with chemo or radiofrequency ablation for liver tumors. A relatively noninvasive procedure, this provides an alternative to the more invasive and costly computed tomography (CT) or magnetic resonance imaging (MRI) exams. We also perform many other services, such as: Fine-needle aspiration of the thyroid, parathyroid, and soft tissue masses Thyroid and parathyroid imaging Lymph node mapping prior to thyroidectomy, and screening for metastatic disease after a thyroidectomy Musculoskeletal ultrasound for ligament and tendon tears and joint abnormalities Evaluation of the anal sphincter and rectal cancer staging with transrectal ultrasound using the 360° Endorectal Probe Gynecological ultrasound, including first-trimester imaging, ovarian cancer screening, sonohysterography (ultrasound of the uterus), HyCoSy (ultrasound of the fallopian tubes), and other gynecologic imaging exams

The Center for Thoracic Cancers at Smilow Cancer Hospital consists of a multidisciplinary team of experts dedicated to providing evaluation of and treatment for patients with a thoracic malignancy, including lung cancer, esophageal cancer, thymoma, or chest wall tumors. Patients in Connecticut and beyond have access to nationally recognized expert clinicians, who provide an organized, collaborative approach to cancer care, as well as the latest technologies and treatments. Our team consists of a collaboration of specialty physicians, including medical oncology, radiation oncology, thoracic surgery, pulmonary medicine, digestive diseases, pathology, diagnostic imaging, and nursing. In addition to our expert clinicians, patients also receive comprehensive care to help with the physical, emotional, and psychological issues that are part of confronting cancer. Patients also benefit from the attention of the team's care coordinators, who make management of even the most detailed multidisciplinary treatment plan less complicated. Our team is active in clinical research, and focuses on developing advances to care in areas of thoracic oncology where the standard treatment needs improvement and where the optimal treatment approach remains unclear. To provide the best care, most of our patients are enrolled in a clinical trial where they can receive innovative therapy for their advanced disease, including immunotherapy, which was first used in clinical trials at Smilow Cancer Hospital. The Center for Thoracic Cancers offers second opinions that are easy, convenient, and all done remotely. Call (203) 200-LUNG for more information and learn how to schedule a second opinion appointment with one of our providers. Medical Oncology Our medical oncologists are nationally recognized for their leadership and expertise in lung cancer treatment and research, and are dedicated to offering personalized treatment options. Biomarker testing is often performed on the tumor to look for specific mutations that can be targeted by medication. There are currently FDA-approved lung cancer treatments for tumors showing abnormalities in EGFR, KRAS, ALK, ROS1, BRAF V600E, MET, RET , and NTRK genes. Recent studies conducted at Yale have led to FDA approval of drugs for the treatment of lung cancer, such as the immunotherapy drug Tecentriq (atezolizumab), which has been proven to improve patient survival for newly diagnosed NSCLC. This drug is designed to block PD-L1, a protein that was discovered by scientists at Yale and that has been instrumental in improving survival for lung cancer patients. Another FDA-approved drug, osimertinib, which stemmed from Yale Cancer Center and Smilow Cancer Hospital researchers, was approved for the treatment of adults with early-stage NSCLC with EGFR gene mutations. Surgery Many patients in need of surgery are referred for a minimally invasive surgery known as a video-assisted thoracoscopi