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Transplant & Immunology

Our Transplant Surgery team provides a comprehensive evaluation and diagnosis for patients with end-stage liver, kidney diseases, and pancreas organ failure. This includes tissue typing and immune evaluation services; leading-edge treatment options for immunosuppression; and follow-up and psychosocial support. We are committed to offer hope and innovative treatments for organ transplant candidates, including those at high risk or turned away by other centers.

Distinguishing Factors

  • Yale New Haven Transplantation Center was the first Connecticut institution to provide liver, kidney, and pancreas transplantation services.
  • The first kidney paired exchange in Connecticut.
  • The first split-liver transplant in the state
  • The largest kidney transplantation program in New England; the largest living donor kidney transplantation program in New England
  • A nationally recognized pediatric liver transplant program in both patient outcomes and number of living donor transplants performed.

Our Approach

Many inherited metabolic liver diseases such as Wilson's disease, Gaucher's disease, lipidosis, alpha-1 antitrypsin deficiency, hemochromatosis, tyrosinemia, and glycogen storage diseases are cured by successful liver transplantation. We specialize in genetic testing for liver diseases and treatments that provide comprehensive care for affected patients. Even though we treat some of the most seriously ill patients, our program's survival rates are consistently higher than the national average.

We offer many options for advanced liver disease, including living donor and deceased donor transplantation, liver transplantation in HIV-infected individuals, and pre- and post-transplant antiviral therapy to prevent or treat recurrent hepatitis C.

Through our acute liver failure program, we can transfer patients to Yale New Haven Hospital in a timely manner for transplant evaluation and medical management. In collaboration with the hospital’s Medical Intensive Care Unit, we offer innovative techniques such as hypothermia therapy for the treatment of acute liver failure.

Pancreatic transplants are less common than kidney or liver transplants and are usually performed in patients with type 1 diabetes. Our physicians perform isolated pancreas transplantation, simultaneous kidney/pancreas transplantation, and pancreas transplantation following kidney transplantation.