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Intestinal Immunity in Neurologic Disease

  • Study HIC#:2000033081
  • Last Updated:10/16/2024

Emerging research is connecting changes in the gut (for example, the types of microbes living there) to changes in the brain. These links between the gut and brain may be the reasons why certain neurologic diseases develop. Yale researchers are studying immune cells in the gut and those in the brain, and we are recruiting patients to help unravel the relationships between these systems.

Study participants will undergo colonoscopy with intestinal biopsies as well as a blood draw. Study participants may have a neurologic disease (like Parkinson’s or MS), or they may be healthy. Participants may be able to contribute to the study during their regularly scheduled screening colonoscopy, or they may choose to have a colonoscopy specifically for research. Participants may also be invited to donate additional biospecimens to our Neurology Data Registry and Biorepository (HIC 2000027291). Compensation is provided.

To learn more, please email us at MSResearch@yale.edu.

    Contact Us

    For more information about this study, including how to volunteer, contact:

    Help Us Discover!

    You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

    Trial Purpose and Description

    Emerging research is connecting changes in the gut (for example, the types of microbes living there) to changes in the brain. These links between the gut and brain may be the reasons why certain neurologic diseases develop. Yale researchers are studying immune cells in the gut and those in the brain, and we are recruiting patients to help unravel the relationships between these systems.

    Study participants will undergo colonoscopy with intestinal biopsies as well as a blood draw. Study participants may have a neurologic disease (like Parkinson’s or MS), or they may be healthy. Participants may be able to contribute to the study during their regularly scheduled screening colonoscopy, or they may choose to have a colonoscopy specifically for research. Participants may also be invited to donate additional biospecimens to our Neurology Data Registry and Biorepository (HIC 2000027291). Compensation is provided.

    To learn more, please email us at MSResearch@yale.edu.

    Eligibility Criteria

    Due for a routine colonoscopy

    Principal Investigator

    For more information about this study, including how to volunteer, contact: