- Yale NeurosurgeryYale Physicians Building800 Howard Avenue, Ste Lower LevelNew Haven, CT 06519
Veronica Chiang, MD, FAANS
Biography
Veronica Chiang MD, a neurosurgeon and director of the Gamma Knife Center at Yale New Haven Hospital, specializes in treating metastatic cancer to the brain using a multidisciplinary approach. She offers both standard neurosurgical surgery as well as cutting edge procedures such as laser thermocoagulation. In addition, she specializes in the use of radiosurgery. This technique allows doctors to transmit radiation directly to tumor cells and avoid radiating healthy brain cells, which can help improve patients’ quality of life after treatment.
Dr. Chiang acknowledges that brain surgery can be a big step for patients and provides as much information about the procedure as possible. “Knowledge helps people deal with how scary it might feel,” she says.
In addition to treating patients, Dr. Chiang conducts research on managing patient care through multidisciplinary approaches, and how technologies like thermocoagulation and radiosurgery can help patients with brain metastases. “The neurological system is one of the last areas where there’s very little known about it. I love learning about it and figuring out how to improve patient’s lives,” she says.
Titles
- Professor of Neurosurgery
- Assistant Dean for Admissions, Medical Education
- Associate Vice Chair of Academic Affairs
- Director, Stereotactic Radiosurgery
- Director, Gamma Knife Center, YNHH
- Director, Stereotactic Radiosurgery Fellowship
Education & Training
- FellowJohns Hopkins University School of Medicine (2000)
- ResidentYale University School of Medicine (2000)
- FellowYale-New Haven Hospital (1994)
- MDUniversity of Western Australia (1992)
- BMedSciUniversity of Western Australia
Additional Information
- First Class Honours (Thesis degree BMedSci): (1991)
- Asthma Foundation of Australia Scholarship: (1990)
- National Health and Medical Research Council of Australia Medical Undergraduate Scholarship: (1988)
- AB of Neurological Surgery, Neurological Surgery (2003, recertified: 2014)
- Kandigian S, Chande S, Dolezal D, Tang T, Wang D, Arnal-Estapé A, Cheok S, McGuone D, Liu Y, Goldberg S, Blondin N, Chiang V, Nguyen D. BSLM-10 MOLECULAR AND HISTOLOGICAL CHARACTERIZATION OF NSCLC PROGRESSION TO LEPTOMENINGEAL METASTASIS WITH COMORBID INTRAPARENCHYMAL DISEASE. Neuro-Oncology Advances 2024, 6: i7-i7. PMCID: PMC11296776, DOI: 10.1093/noajnl/vdae090.020.
- Mahajan A, Goldberg S, Weiss S, Tran T, Singh K, Joshi K, Aboian M, Kluger H, Chiang V. Patterns of brain metastases response to immunotherapy with pembrolizumab. Journal Of Neuro-Oncology 2024, 169: 555-561. PMID: 38963658, DOI: 10.1007/s11060-024-04754-8.
- Robert S, Kiziltug E, Lu B, Arnal-Estape A, Nguyen D, Chiang V. 154 Elucidating the Immune Landscape of Radiation Necrosis Through Single Cell Analysis of Recurrent Brain Lesions in Patients After Stereotactic Radio Surgery. Neurosurgery 2024, 70: 35-36. DOI: 10.1227/neu.0000000000002809_154.
- Nagpal S, Milano M, Chiang V, Soltys S, Brackett A, Halasz L, Garg A, Sahgal A, Ahluwalia M, Tom M, Palmer J, Knisely J, Chao S, Gephart M, Wang T, Lo S, Chang E. Executive summary of the American Radium Society appropriate use criteria for brain metastases in epidermal growth factor receptor mutated-mutated and ALK-fusion non-small cell lung cancer. Neuro-Oncology 2024, 26: 1195-1212. PMID: 38459978, PMCID: PMC11226873, DOI: 10.1093/neuonc/noae041.
- Chiang V, Pugazenthi S, Leidig W, Rodriguez A, Prabhu S, Haskell-Mendoza A, Fecci P, Placantonakis D, Abram S, Lega B, Kim A. Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series. Journal Of Neurosurgery 2024, 141: 642-652. PMID: 38457795, DOI: 10.3171/2023.12.jns231542.
- Strowd R, Chan M, Tatter S, Chiang V, Fecci P, Prabhu S, Hadjipanayis C, Kirkpatrick J, Sun D, Sinicrope K, Mohammadi A, Sevak P, Abram S, Kim A, Leuthardt E, Chao S, Phillips J, Lacroix M, Williams B, Placantonakis D, Silverman J, Baumgartner J, Piccioni D, Laxton A. SURG-32. EFFICACY OF LASER INTERSTITIAL THERMAL THERAPY (LITT) FOR BIOPSY-PROVEN RADIATION NECROSIS IN RADIOGRAPHICALLY RECURRENT BRAIN METASTASES. Neuro-Oncology 2023, 25: v269-v269. PMCID: PMC10640195, DOI: 10.1093/neuonc/noad179.1031.
- Singh C, Theriault B, An Y, Yu J, Knisely J, Shepard M, Wegner R, Warnick R, Peker S, Samanci Y, Trifiletti D, Lee C, Yang H, Bernstein K, Kondziolka D, Tripathi M, Mathieu D, Mantziaris G, Pikis S, Sheehan J, Chiang V. Selected-Lesion SRS as a Novel Strategy in Treatment of Patients with Multiple Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2023, 117: e150-e151. DOI: 10.1016/j.ijrobp.2023.06.971.
- Mange A, Singh C, Theriault B, Hansen J, An Y, Aneja S, Chiang V. Selected-Lesion Stereotactic Radiosurgery in Treatment of Patients with Multiple Brain Metastases: A Single Institution Retrospective Study. International Journal Of Radiation Oncology • Biology • Physics 2023, 117: e135. DOI: 10.1016/j.ijrobp.2023.06.939.
- Kaur M, Petersen G, Jekel L, von Reppert M, Varghese S, de Oliveira Santo I, Avesta A, Aneja S, Omuro A, Chiang V, Aboian M. PACS-Integrated Tools for Peritumoral Edema Volumetrics Provide Additional Information to RANO-BM-Based Assessment of Lung Cancer Brain Metastases after Stereotactic Radiotherapy: A Pilot Study. Cancers 2023, 15: 4822. PMID: 37835516, PMCID: PMC10571649, DOI: 10.3390/cancers15194822.
- Theriault B, Singh C, Yu J, Knisely J, Shepard M, Wegner R, Warnick R, Peker S, Samanci Y, Trifiletti D, Lee C, Yang H, Bernstein K, Kondziolka D, Tripathi M, Mathieu D, Mantziaris G, Pikis S, Sheehan J, Chiang V. Selected-Lesion Stereotactic Radiosurgery (SL-SRS) as a Novel Strategy in the Treatment of Patients With Multiple Brain Metastases. Cureus 2023, 15: e45457. PMID: 37859877, PMCID: PMC10583225, DOI: 10.7759/cureus.45457.
- Kotecha R, Chiang V, Tom M, Nabavizadeh A, Zan E, Peddi S, Sulman E, Siegel B, Huang J, Brem S, Ware M, Kesari S, Parent E, Pope W, Holmes R, Chau A, Teoh E, Chao S, Aboian M. JS09.5.A18F-FLUCICLOVINE PET FOR DETECTION OF RECURRENT BRAIN METASTASES AFTER RADIATION THERAPY: IMAGE INTERPRETATION CRITERIA RESULTS FROM PURSUE, A PROSPECTIVE PHASE 2 TRIAL. Neuro-Oncology 2023, 25: ii12-ii13. PMCID: PMC10489492, DOI: 10.1093/neuonc/noad137.034.
- Kotecha R, Chiang V, Tom M, Nabavizadeh A, Zan E, Peddi S, Sulman E, Siegel B, Huang J, Brem S, Ware M, Kesari S, Parent E, Pope W, Holmes R, Chau A, Teoh E, Chao S, Aboian M. NEIM-05 PURSUE: RESULTS FROM A PROSPECTIVE, PHASE 2B TRIAL TO DEFINE IMAGE INTERPRETATION CRITERIA FOR18F-FLUCICLOVINE-PET FOR DETECTION OF RECURRENT BRAIN METASTASES AFTER RADIATION THERAPY. Neuro-Oncology Advances 2023, 5: iii15-iii15. PMCID: PMC10402431, DOI: 10.1093/noajnl/vdad070.057.
- Lu B, Lucca L, DiStasio M, Liu Y, Pham G, Buitrago-Pocasangre N, Arnal-Estape A, Moliterno J, Chiang V, Omuro A, Hafler D. BSBM-18 SINGLE-CELL PROFILING TUMOR-INFILTRATING IMMUNE CELLS REVEALS CXCL13+ FOLLICULAR HELPER-LIKE CD4+ T CELLS IN HUMAN BRAIN TUMORS. Neuro-Oncology Advances 2023, 5: iii4-iii4. PMCID: PMC10402449, DOI: 10.1093/noajnl/vdad070.014.
- Kotecha R, Chiang V, Tom M, Nabavizadeh A, Zan E, Peddi S, Sulman E, Siegel B, Huang J, Brem S, Ware M, Kesari S, Parent E, Pope W, Holmes R, Chau A, Teoh E, Chao S, Aboian M. Evaluating the diagnostic performance of 18F-fluciclovine for detection of recurrent brain metastases after radiation therapy: Results from a prospective phase 2 trial. Journal Of Clinical Oncology 2023, 41: 2001-2001. DOI: 10.1200/jco.2023.41.16_suppl.2001.
- Corbin Z, Liu Y, Fulbright R, Thaw-Poon S, Baehring J, Blondin N, Kim P, Omuro A, Chiang V, Moliterno J, Omay S, Piepmeier J, Rothman D, de Graaf R, De Feyter H. Imaging metabolism of deuterated glucose in patients with primary brain tumors. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0142.
- Kaur M, Cassinelli G, von Reppert M, Jekel L, Varghese S, Dixe I, Omuro A, Chiang V, Aboian M. Peritumoral edema measurements provide additional information to RANO-BM based assessment of lung cancer brain metastases after Gamma Knife therapy (P10-13.002). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203091.
- Tran T, Caulfield J, Zhang L, Schoenfeld D, Djureinovic D, Chiang V, Oria V, Weiss S, Olino K, Jilaveanu L, Kluger H. Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma. JCI Insight 2023, 8: e157347. PMID: 36821392, PMCID: PMC10132152, DOI: 10.1172/jci.insight.157347.
- Robert S, Lu B, Arnal-Estape A, Nguyen D, Chiang V. 465 Defining the Immune Profile of Radiation Necrosis Through Single-cell Analysis of Intracranial Lesions. Neurosurgery 2023, 69: 97-98. DOI: 10.1227/neu.0000000000002375_465.
- Xu S, Campbell A, Chiang V, Bindra R, Vasquez J, Pashankar F. Use of stereotactic radiosurgery in treatment of brain metastases from pediatric extracranial solid tumors. Pediatric Blood & Cancer 2023, 70: e30303. PMID: 36975152, DOI: 10.1002/pbc.30303.
- Singh R, Bowden G, Mathieu D, Perlow H, Palmer J, Elhamdani S, Shepard M, Liang Y, Nabeel A, Reda W, Tawadros S, Abdelkarim K, El-Shehaby A, Emad R, Elazzazi A, Warnick R, Gozal Y, Daly M, McShane B, Addis-Jackson M, Karthikeyan G, Smith S, Picozzi P, Franzini A, Kaisman-Elbaz T, Yang H, Wei Z, Legarreta A, Hess J, Templeton K, Pikis S, Mantziaris G, Simonova G, Liscak R, Peker S, Samanci Y, Chiang V, Niranjan A, Kersh C, Lee C, Trifiletti D, Lunsford L, Sheehan J. Local Control and Survival Outcomes After Stereotactic Radiosurgery for Brain Metastases From Gastrointestinal Primaries: An International Multicenter Analysis. Neurosurgery 2023, 93: 592-598. PMID: 36942965, DOI: 10.1227/neu.0000000000002456.
- Draeger E, Chen Z, Hansen J, Chiang V, Tien C. Preliminary dosimetric comparison between fixed and rotating source stereotactic radiosurgery systems. Journal Of Applied Clinical Medical Physics 2023, 24: e13907. PMID: 36660774, PMCID: PMC10161057, DOI: 10.1002/acm2.13907.
- Lamsam L, Brigido M, Sivaraju A, Hirsch L, Spencer D, Chiang V, Damisah E. Transfrontal Approach to the Amygdala for Ablation With Laser Interstitial Thermal Therapy: An Epilepsy Case Report. Operative Neurosurgery 2023, 24: e381-e384. PMID: 36715982, PMCID: PMC10158899, DOI: 10.1227/ons.0000000000000576.
- Merkin R, Chiang V, Goldberg S. Management of patients with brain metastases from NSCLC without a genetic driver alteration: upfront radiotherapy or immunotherapy? Therapeutic Advances In Medical Oncology 2023, 15: 17588359231175438. PMID: 37275964, PMCID: PMC10233588, DOI: 10.1177/17588359231175438.
- Chan M, Tatter S, Chiang V, Fecci P, Strowd R, Prabhu S, Hadjipanayis C, Kirkpatrick J, Sun D, Sinicrope K, Mohammadi A, Sevak P, Abram S, Kim A, Leuthardt E, Chao S, Phillips J, Lacroix M, Williams B, Placantonakis D, Silverman J, Baumgartner J, Piccioni D, Laxton A. Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases. Neuro-Oncology Advances 2023, 5: vdad031. PMID: 37114245, PMCID: PMC10129388, DOI: 10.1093/noajnl/vdad031.
- Wandrey N, Gao D, Robin T, Contessa J, Singh C, Chiang V, Li J, Chen A, Wang Y, Sheehan J, Dutta S, Weiss S, Paly J, Rusthoven C. Multicenter analysis of stereotactic radiosurgery for multiple brain metastases from EGFR and ALK driven non-small cell lung cancer. Lung Cancer 2022, 176: 144-148. PMID: 36641932, PMCID: PMC10552603, DOI: 10.1016/j.lungcan.2022.11.019.
- Adua S, Arnal-Estapé A, Zhao M, Qi B, Liu Z, Kravitz C, Hulme H, Strittmatter N, López-Giráldez F, Chande S, Albert A, Melnick M, Hu B, Politi K, Chiang V, Colclough N, Goodwin R, Cross D, Smith P, Nguyen D. Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature Communications 2022, 13: 7690. PMID: 36509758, PMCID: PMC9744876, DOI: 10.1038/s41467-022-34889-z.
- Kowalchuk R, Niranjan A, Hess J, Antonios J, Zhang M, Braunstein S, Ross R, Pikis S, Deibert C, Lee C, Yang H, Langlois A, Mathieu D, Peker S, Samanci Y, Rusthoven C, Chiang V, Wei Z, Lunsford L, Trifiletti D, Sheehan J. Stereotactic radiosurgery and local control of brain metastases from triple-negative breast cancer. Journal Of Neurosurgery 2022, 138: 1608-1614. PMID: 36433878, DOI: 10.3171/2022.10.jns221900.
- Robert S, Lu B, Kiziltug E, Estape A, Nguyen D, Chiang V. IMMU-01. DEFINING THE IMMUNE PROFILE OF RADIATION NECROSIS THROUGH SINGLE-CELL ANALYSIS OF INTRACRANIAL LESIONS. Neuro-Oncology 2022, 24: vii131-vii131. DOI: 10.1093/neuonc/noac209.499.
- de Groot J, Kim A, Prabhu S, Rao G, Laxton A, Fecci P, O'Brien B, Sloan A, Chiang V, Tatter S, Mohammadi A, Placantonakis D, Strowd R, Chen C, Hadjipanayis C, Khasraw M, Sun D, Piccioni D, Sinicrope K, Campian J, Kurz S, Williams B, Smith K, Tovar-Spinoza Z, Leuthardt E. SURG-23. EFFICACY OF LASER INTERSTITIAL THERMAL THERAPY (LITT) FOR NEWLY DIAGNOSED AND RECURRENT IDH WILD-TYPE GLIOBLASTOMA. Neuro-Oncology 2022, 24: vii256-vii257. PMCID: PMC9660753, DOI: 10.1093/neuonc/noac209.989.
- Kaur M, Petersen G, von Reppert M, Jekel L, de Santo I, Varghese S, Chiang V, Aboian M. NIMG-04. LONGITUDINAL TRACKING OF PERITUMORAL EDEMA VOLUME USING PACS-INTEGRATED TOOLS PROVIDES CRITICAL INFORMATION IN TREATMENT ASSESSMENT OF NSCLC BRAIN METASTASES AFTER RADIOSURGERY. Neuro-Oncology 2022, 24: vii162-vii162. PMCID: PMC9661156, DOI: 10.1093/neuonc/noac209.624.
- Kaur M, Varghese S, Jekel L, Tillmanns N, Merkaj S, Bousabarah K, Lin M, Bhawnani J, Chiang V, Aboian M. NIMG-07. APPLYING A GLIOMA-TRAINED DEEP LEARNING AUTO-SEGMENTATION TOOL ON BM PRE- AND POST-RADIOSURGERY. Neuro-Oncology 2022, 24: vii162-vii163. PMCID: PMC9660643, DOI: 10.1093/neuonc/noac209.626.
- Jekel L, Bousabarah K, Lin M, Merkaj S, Kaur M, Avesta A, Aneja S, Omuro A, Chiang V, Scheffler B, Aboian M. NIMG-02. PACS-INTEGRATED AUTO-SEGMENTATION WORKFLOW FOR BRAIN METASTASES USING NNU-NET. Neuro-Oncology 2022, 24: vii162-vii162. PMCID: PMC9661012, DOI: 10.1093/neuonc/noac209.622.
- Fomchenko EI, Leelatian N, Darbinyan A, Huttner AJ, Chiang VL. Histological changes associated with laser interstitial thermal therapy for radiation necrosis: illustrative cases. Journal Of Neurosurgery Case Lessons 2022, 4: case21373. PMID: 35855352, PMCID: PMC9257400, DOI: 10.3171/case21373.
- Aizer AA, Lamba N, Ahluwalia MS, Aldape K, Boire A, Brastianos PK, Brown PD, Camidge DR, Chiang VL, Davies MA, Hu LS, Huang RY, Kaufmann T, Kumthekar P, Lam K, Lee EQ, Lin NU, Mehta M, Parsons M, Reardon DA, Sheehan J, Soffietti R, Tawbi H, Weller M, Wen PY. Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions. Neuro-Oncology 2022, 24: 1613-1646. PMID: 35762249, PMCID: PMC9527527, DOI: 10.1093/neuonc/noac118.
- Tom MC, Milano MT, Chao ST, Soltys SG, Knisely JPS, Sahgal A, Nagpal S, Lo SS, Jabbari S, Wang TJC, Ahluwalia MS, Simonson M, Palmer JD, Gephart MH, Halasz LM, Garg AK, Chiang VLS, Chang EL. Executive summary of American Radium Society’s appropriate use criteria for the postoperative management of lower grade gliomas. Radiotherapy And Oncology 2022, 170: 79-88. PMID: 35367527, DOI: 10.1016/j.radonc.2022.03.018.
- Shahsavari N, Ahmad M, Sekar V, Meola A, Hancock SL, Chang SD, Chiang VL. Synchronous glioblastoma and brain metastases: illustrative case. Journal Of Neurosurgery Case Lessons 2022, 3: case21714. PMID: 36273867, PMCID: PMC9379681, DOI: 10.3171/case21714.
- Sperduto PW, De B, Li J, Carpenter D, Kirkpatrick J, Milligan M, Shih HA, Kutuk T, Kotecha R, Higaki H, Otsuka M, Aoyama H, Bourgoin M, Roberge D, Dajani S, Sachdev S, Gainey J, Buatti JM, Breen W, Brown PD, Ni L, Braunstein S, Gallitto M, Wang TJC, Shanley R, Lou E, Shiao J, Gaspar LE, Tanabe S, Nakano T, An Y, Chiang V, Zeng L, Soliman H, Elhalawani H, Cagney D, Thomas E, Boggs DH, Ahluwalia MS, Mehta MP. Graded Prognostic Assessment (GPA) for Patients With Lung Cancer and Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA Including the Effect of Programmed Death Ligand 1 and Other Prognostic Factors. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: 60-74. PMID: 35331827, PMCID: PMC9378572, DOI: 10.1016/j.ijrobp.2022.03.020.
- Jekel L, Brim WR, von Reppert M, Staib L, Petersen G, Merkaj S, Subramanian H, Zeevi T, Payabvash S, Bousabarah K, Lin M, Cui J, Brackett A, Mahajan A, Omuro A, Johnson MH, Chiang VL, Malhotra A, Scheffler B, Aboian MS. Machine Learning Applications for Differentiation of Glioma from Brain Metastasis—A Systematic Review. Cancers 2022, 14: 1369. PMID: 35326526, PMCID: PMC8946855, DOI: 10.3390/cancers14061369.
- Cheok S, Arnal-Estape A, Wei W, Nguyen D, Chiang V. 513 Surveilling Cerebrospinal Fluid Protein Biomarkers in Brain Metastasis. Neurosurgery 2022, 68: 129-129. DOI: 10.1227/neu.0000000000001880_513.
- Alvi MA, Asher AL, Michalopoulos GD, Grills IS, Warnick RE, McInerney J, Chiang VL, Attia A, Timmerman R, Chang E, Kavanagh BD, Andrews DW, Walter K, Bydon M, Sheehan JP. Factors associated with progression and mortality among patients undergoing stereotactic radiosurgery for intracranial metastasis: results from a national real-world registry. Journal Of Neurosurgery 2022, 137: 985-998. PMID: 35171833, DOI: 10.3171/2021.10.jns211410.
- Petersen G, Bousabarah K, Verma T, von Reppert M, Jekel L, Gordem A, Jang B, Merkaj S, Fadel S, Owens R, Omuro A, Chiang V, Ikuta I, Lin M, Aboian MS. Real-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery. Neuro-Oncology Advances 2022, 4: vdac116. PMID: 36043121, PMCID: PMC9412827, DOI: 10.1093/noajnl/vdac116.
- Grabowski MM, Srinivasan ES, Vaios EJ, Sankey EW, Otvos B, Krivosheya D, Scott A, Olufawo M, Ma J, Fomchenko EI, Herndon JE, Kim AH, Chiang VL, Chen CC, Leuthardt EC, Barnett GH, Kirkpatrick JP, Mohammadi AM, Fecci PE. Combination laser interstitial thermal therapy plus stereotactic radiotherapy increases time to progression for biopsy-proven recurrent brain metastases. Neuro-Oncology Advances 2022, 4: vdac086. PMID: 35795470, PMCID: PMC9248774, DOI: 10.1093/noajnl/vdac086.
- de Groot JF, Kim AH, Prabhu S, Rao G, Laxton AW, Fecci PE, O’Brien B, Sloan A, Chiang V, Tatter SB, Mohammadi AM, Placantonakis DG, Strowd RE, Chen C, Hadjipanayis C, Khasraw M, Sun D, Piccioni D, Sinicrope KD, Campian JL, Kurz SC, Williams B, Smith K, Tovar-Spinoza Z, Leuthardt EC. Efficacy of laser interstitial thermal therapy (LITT) for newly diagnosed and recurrent IDH wild-type glioblastoma. Neuro-Oncology Advances 2022, 4: vdac040. PMID: 35611270, PMCID: PMC9122789, DOI: 10.1093/noajnl/vdac040.
- Cifarelli C, Vargo J, Fang W, Liscak R, Guseynova K, Warnick R, Lee C, Yang H, Borghei-Razavi H, Maiti T, Siddiqui Z, Yuan J, Grills I, Mathieu D, Touchette C, Cordeiro D, Chiang V, Hess J, Tien C, Faramand A, Kano H, Barnett G, Sheehan J, Lunsford L. Role of Gamma Knife Radiosurgery in Small Cell Lung Cancer: A Multi-Institutional Retrospective Study of the International Radiosurgery Research Foundation (IRRF). Neurosurgery 2021, 89: s20-s20. DOI: 10.1093/neuros/nyz428_s020.
- Kim A, Tatter S, Rao G, Prabhu S, Chen C, Fecci P, Chiang V, Smith K, Williams B, Mohammadi A, Judy K, Sloan A, Tovar-Spinoza Z, Baumgartner J, Hadjipanayis C, Leuthardt E. Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (LAANTERN): 12-Month Outcomes and Quality of Life After Brain Tumor Ablation. Neurosurgery 2021, 89: s16-s16. PMCID: PMC8600280, DOI: 10.1093/neuros/nyaa071_s016.
- Cheok S, Hansen J, Chiang V. Recognition and Management of Adverse Radiation Effects. 2021, 391-404. DOI: 10.1201/9781003167464-36.
- Lu BY, Gupta R, Aguirre-Ducler A, Gianino N, Wyatt H, Ribeiro M, Chiang VL, Contessa JN, Adeniran AJ, Jilaveanu LB, Kluger HM, Schalper KA, Goldberg SB. Spatially resolved analysis of the T cell immune contexture in lung cancer-associated brain metastases. Journal For ImmunoTherapy Of Cancer 2021, 9: e002684. PMID: 34670827, PMCID: PMC8529973, DOI: 10.1136/jitc-2021-002684.
- Kowalchuk RO, Niranjan A, Lee CC, Yang HC, Liscak R, Guseynova K, Tripathi M, Kumar N, Peker S, Samanci Y, Hess J, Chiang V, Iorio-Morin C, Mathieu D, Pikis S, Wei Z, Lunsford LD, Trifiletti DM, Sheehan JP. Reirradiation With Stereotactic Radiosurgery After Local or Marginal Recurrence of Brain Metastases From Previous Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2021, 112: 726-734. PMID: 34644606, DOI: 10.1016/j.ijrobp.2021.10.008.
- Collier E, Chiang V, Goldberg S. Management of Brain Metastases. Current Cancer Research 2021, 115-137. DOI: 10.1007/978-3-030-74028-3_6.
- Seymour ZA, Chan JW, McDermott MW, Grills I, Ye H, Kano H, Lehocky CA, Jacobs RC, Lunsford LD, Chytka T, Liščák R, Lee CC, Yang HC, Ding D, Sheehan JP, Feliciano CE, Rodriguez-Mercado R, Chiang VL, Hess JA, Sommaruga S, McShane B, Lee JYK, Vasas LT, Kaufmann AM, Sneed PK. Adverse radiation effects in volume-staged radiosurgery for large arteriovenous malformations: a multiinstitutional study. Journal Of Neurosurgery 2021, 136: 503-511. PMID: 34450589, DOI: 10.3171/2020.12.jns201866.
- Sandhu MRS, Chiang VL, Tran T, Yu JB, Weiss SA, Goldberg SB, Aboian MS, Kluger HM, Mahajan A. Correction to: Incidence and characteristics of metastatic intracranial lesions in stage III and IV melanoma: a single institute retrospective analysis. Journal Of Neuro-Oncology 2021, 154: 205-205. PMID: 34403041, DOI: 10.1007/s11060-021-03825-4.
- Pena-Pino I, Ma J, Hori Y, Fomchenko E, Dusenbery K, Reynolds M, Wilke C, Yuan J, Barnett G, Chiang V, Mohammadi A, Chen C. SURG-02. Stereotactic Laser Ablation (SLA) followed by consolidation stereotactic radiosurgery (SRS) as a treatment strategy for brain metastasis that recurred locally after initial radiosurgery (BMRS): a collaborative institutional experience. Neuro-Oncology Advances 2021, 3: iii23-iii23. PMCID: PMC8351296, DOI: 10.1093/noajnl/vdab071.095.
- Sandhu MRS, Chiang VL, Tran T, Yu JB, Weiss S, Goldberg S, Aboian M, Kluger HM, Mahajan A. Incidence and characteristics of metastatic intracranial lesions in stage III and IV melanoma: a single institute retrospective analysis. Journal Of Neuro-Oncology 2021, 154: 197-203. PMID: 34351544, DOI: 10.1007/s11060-021-03813-8.
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- Qian J, Yu J, Gettinger S, Chiang V. Ceritinib enables stereotactic radiosurgery to a previously untreatable symptomatic brain metastasis in a patient with ALK rearranged non-small cell lung cancer. Cancer Treatment And Research Communications 2016, 6: 17-19. DOI: 10.1016/j.ctrc.2016.02.002.
- Colaco RJ, Yu JB, Bond JS, Bindra RS, Contessa JN, Knisely JPS, Chiang VL. A contemporary dose selection algorithm for stereotactic radiosurgery in the treatment of brain metastases - An initial report. Journal Of Radiosurgery And SBRT 2016, 4: 43-52. PMID: 29296425, PMCID: PMC5658834.
- Taylor BF, Knisely JP, Qian JM, Yu JB, Chiang VL. Predicting treatment related imaging changes (TRICs) after radiosurgery for brain metastases using treatment dose and conformality metrics. Journal Of Radiosurgery And SBRT 2016, 4: 53-60. PMID: 29296426, PMCID: PMC5658837.
- Rutter CE, Johung KL, Yao X, Lu AY, Jilaveanu LB, Yu JB, Contessa JN, Kluger HM, Chiang VLS, Bindra RS. Demonstration of differential radiosensitivity based upon mutation profile in metastatic melanoma treated with stereotactic radiosurgery. Journal Of Radiosurgery And SBRT 2016, 4: 97-106. PMID: 29296434, PMCID: PMC5658871.
- Chiang VL, Knisely JP. Top 25 cited articles on Gamma Knife surgery published since 2005 in journals of the American Association of Neurological Surgeons. Journal Of Neurosurgery 2015, 123 Spec Suppl: 1-2. PMID: 26620469, DOI: 10.3171/2015.12.jnsleksellintro.
- Mohammadi A, Chiang V, Beaumont T, Elson P, Barnett G, Leuthardt E. SURG-20A MULTICENTER SURVIVAL ANALYSIS OF UPFRONT LASER-ABLATION FOR TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA. Neuro-Oncology 2015, 17: v218-v218. PMCID: PMC4639277, DOI: 10.1093/neuonc/nov235.20.
- Colaco RJ, Martin P, Kluger HM, Yu JB, Chiang VL. Does immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases? Journal Of Neurosurgery 2015, 125: 17-23. PMID: 26544782, DOI: 10.3171/2015.6.jns142763.
- Park H, Wang E, Rutter C, Corso C, Chiang V, Yu J. Shifts in Stereotactic Radiosurgery Platform Utilization for Brain Metastases in the United States. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e62. DOI: 10.1016/j.ijrobp.2015.07.701.
- Jairam V, Chiang V, Yu J. Prognostic Factors for Seizures After First Radiosurgical Treatment in Patients With Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e100. DOI: 10.1016/j.ijrobp.2015.07.802.
- Park H, Colaco R, Laurans M, Chiang V, Yu J, Husain Z. Spine Stereotactic Body Radiation Therapy Outcomes in Patients With Concurrent Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e62. DOI: 10.1016/j.ijrobp.2015.07.702.
- Park HS, Wang EH, Rutter CE, Corso CD, Chiang VL, Yu JB. Changing practice patterns of Gamma Knife versus linear accelerator-based stereotactic radiosurgery for brain metastases in the US. Journal Of Neurosurgery 2015, 124: 1018-24. PMID: 26473783, DOI: 10.3171/2015.4.jns1573.
- Johung KL, Yeh N, Desai NB, Williams TM, Lautenschlaeger T, Arvold ND, Ning MS, Attia A, Lovly CM, Goldberg S, Beal K, Yu JB, Kavanagh BD, Chiang VL, Camidge DR, Contessa JN. Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastasis. Journal Of Clinical Oncology 2015, 34: 123-129. PMID: 26438117, PMCID: PMC5070549, DOI: 10.1200/jco.2015.62.0138.
- Sheehan JP, Cohen-Inbar O, Ruangkanchanasetr R, Bulent Omay S, Hess J, Chiang V, Iorio-Morin C, Alonso-Basanta M, Mathieu D, Grills IS, Lee JY, Lee CC, Dade Lunsford L. Post-radiosurgical edema associated with parasagittal and parafalcine meningiomas: a multicenter study. Journal Of Neuro-Oncology 2015, 125: 317-324. PMID: 26329323, DOI: 10.1007/s11060-015-1911-1.
- Goldberg SB, Contessa JN, Omay SB, Chiang V. Lung Cancer Brain Metastases. The Cancer Journal 2015, 21: 398-403. PMID: 26389765, DOI: 10.1097/ppo.0000000000000146.
- Yushak ML, Chiang VL, Kluger HM. Clinical trials in melanoma patients with brain metastases. Pigment Cell & Melanoma Research 2015, 28: 741-743. PMID: 26205399, PMCID: PMC4834841, DOI: 10.1111/pcmr.12401.
- Kluger HM, Zito CR, Barr ML, Baine MK, Chiang VL, Sznol M, Rimm DL, Chen L, Jilaveanu LB. Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites. Clinical Cancer Research 2015, 21: 3052-3060. PMID: 25788491, PMCID: PMC4490112, DOI: 10.1158/1078-0432.ccr-14-3073.
- Chiang V. Surgery in neuro-oncolgy with a focus on stereotactic radiosurgery. CNS Oncology 2015, 4: 199-201. PMID: 26118857, PMCID: PMC6088336, DOI: 10.2217/cns.15.18.
- Colaco R, Martin P, Chiang V. Evolution of multidisciplinary brain metastasis management: case study and literature review. The Yale Journal Of Biology And Medicine 2015, 88: 157-65. PMID: 26029014, PMCID: PMC4445437.
- Kluger H, Goldberg S, Sznol M, Tsiouris J, Vortmeyer A, Jilaveanu L, Ralabate A, Rivera A, Burke M, Hegbe U, Cohen J, Yao X, Speaker S, Madura M, Knapp-Perry E, Mahajan A, Chiang V. Safety and activity of pembrolizumab in melanoma patients with untreated brain metastases. Journal Of Clinical Oncology 2015, 33: 9009-9009. DOI: 10.1200/jco.2015.33.15_suppl.9009.
- Goldberg S, Gettinger S, Mahajan A, Herbst R, Chiang A, Tsiouris A, Vortmeyer A, Jilaveanu L, Speaker S, Madura M, Rowen E, Gerrish H, Knapp-Perry E, Yao X, Chiang V, Kluger H. Activity and safety of pembrolizumab in patients with metastatic non-small cell lung cancer with untreated brain metastases. Journal Of Clinical Oncology 2015, 33: 8035-8035. DOI: 10.1200/jco.2015.33.15_suppl.8035.
- Sheehan JP, Kano H, Xu Z, Chiang V, Mathieu D, Chao S, Akpinar B, Lee JY, Yu JB, Hess J, Wu HM, Chung WY, Pierce J, Missios S, Kondziolka D, Alonso-Basanta M, Barnett GH, Lunsford LD. Gamma Knife radiosurgery for facial nerve schwannomas: a multicenter study. Journal Of Neurosurgery 2015, 123: 387-94. PMID: 25955875, DOI: 10.3171/2014.11.jns141160.
- Sheehan JP, Starke RM, Kano H, Barnett GH, Mathieu D, Chiang V, Yu JB, Hess J, McBride HL, Honea N, Nakaji P, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD. Gamma Knife radiosurgery for posterior fossa meningiomas: a multicenter study. Journal Of Neurosurgery 2015, 122: 1479-89. PMID: 25859812, DOI: 10.3171/2014.10.jns14139.
- Campbell AM, Glover J, Chiang VL, Gerrard J, Yu JB. Gamma knife stereotactic radiosurgical thalamotomy for intractable tremor: A systematic review of the literature. Radiotherapy And Oncology 2015, 114: 296-301. PMID: 25690750, DOI: 10.1016/j.radonc.2015.01.013.
- Jairam V, Chiang VL, Bond J, Yu JB. Equivalent whole brain dose for patients undergoing gamma knife for multiple lesions. Journal Of Radiosurgery And SBRT 2015, 3: 187-191. PMID: 29296401, PMCID: PMC5746333.
- Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. BM-10SYSTEMIC TREATMENT AND RADIATION NECROSIS FOLLOWING GKSRS IN THE TREATMENT OF BRAIN METASTASES. Neuro-Oncology 2014, 16: v34-v34. PMCID: PMC4217910, DOI: 10.1093/neuonc/nou240.10.
- Ding D, Starke RM, Kano H, Nakaji P, Barnett GH, Mathieu D, Chiang V, Omay SB, Hess J, McBride HL, Honea N, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD, Sheehan JP. Gamma Knife Radiosurgery for Cerebellopontine Angle Meningiomas: A Multicenter Study. Neurosurgery 2014, 75: 398-408. PMID: 24991710, DOI: 10.1227/neu.0000000000000480.
- Colaco R, Yu J, Bond J, Bindra R, Contessa J, Knisely J, Chiang V. Dose Selection Algorithm for Gamma Knife Treatment of Cerebral Metastases: Preliminary Results. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s310-s311. DOI: 10.1016/j.ijrobp.2014.05.1036.
- Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. Systemic Treatment and Radiation Necrosis Following Gamma Knife Radiosurgery in the Treatment of Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s310. DOI: 10.1016/j.ijrobp.2014.05.1035.
- Starke R, Kano H, Ding D, Nakaji P, Barnett GH, Mathieu D, Chiang V, Yu JB, Hess J, McBride HL, Honea N, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD, Sheehan JP. Stereotactic radiosurgery of petroclival meningiomas: a multicenter study. Journal Of Neuro-Oncology 2014, 119: 169-176. PMID: 24821284, DOI: 10.1007/s11060-014-1470-x.
- Sheehan JP, Starke RM, Kano H, Kaufmann AM, Mathieu D, Zeiler FA, West M, Chao ST, Varma G, Chiang VL, Yu JB, McBride HL, Nakaji P, Youssef E, Honea N, Rush S, Kondziolka D, Lee JY, Bailey RL, Kunwar S, Petti P, Lunsford LD. Gamma Knife radiosurgery for sellar and parasellar meningiomas: a multicenter study. Journal Of Neurosurgery 2014, 120: 1268-77. PMID: 24678777, DOI: 10.3171/2014.2.jns13139.
- Nath SK, Sheridan AD, Rauch PJ, Yu JB, Minja FJ, Vortmeyer AO, Chiang VL. Significance of histology in determining management of lesions regrowing after radiosurgery. Journal Of Neuro-Oncology 2014, 117: 303-310. PMID: 24504499, DOI: 10.1007/s11060-014-1389-2.
- Patel T, Chiang V. Laser interstitial thermal therapy for treatment of post-radiosurgery tumor recurrence and radiation necrosis. Photonics And Lasers In Medicine 2014, 3: 95-105. DOI: 10.1515/plm-2013-0057.
- Wang C, Roberts KB, Bindra RS, Chiang VL, Yu JB. Delayed Cerebral Vasculopathy Following Cranial Radiation Therapy for Pediatric Tumors. Pediatric Neurology 2014, 50: 549-556. PMID: 24739378, DOI: 10.1016/j.pediatrneurol.2013.09.018.
- Alomari A, Rauch PJ, Orsaria M, Minja FJ, Chiang VL, Vortmeyer AO. Radiologic and histologic consequences of radiosurgery for brain tumors. Journal Of Neuro-Oncology 2014, 117: 33-42. PMID: 24442402, DOI: 10.1007/s11060-014-1359-8.
- Chiang V, Awad I. Mass Effect. 2014, 1007-1008. DOI: 10.1016/b978-0-12-385157-4.00765-x.
- Kuzmik GA, Michaelides EM, Chiang VL, Nonaka Y, Fukushima T, Vortmeyer AO, Bulsara KR. Rapidly Progressive Epithelioid Malignant Peripheral Nerve Sheath Tumor of the Vestibular Nerve. Otology & Neurotology 2013, 34: 1739-1742. PMID: 23988994, DOI: 10.1097/mao.0b013e31829ab8be.
- Patel TR, Chiang VL. Secondary Neoplasms After Stereotactic Radiosurgery. World Neurosurgery 2013, 81: 594-599. PMID: 24148883, DOI: 10.1016/j.wneu.2013.10.043.
- Rutter C, Giesen E, Yu J, Bindra R, Kluger H, Chiang V. Influence of BRAF and NRAS Mutations on Distant Intracranial Recurrence and Survival in Metastatic Melanoma Following Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s275. DOI: 10.1016/j.ijrobp.2013.06.717.
- Prognostic Factors in Patients With Brain Metastases at Initial Non-Small Cell Lung Cancer DiagnosisRutter C, Mancini B, Yu J, Chiang V, Bindra R. Prognostic Factors in Patients With Brain Metastases at Initial Non-Small Cell Lung Cancer Diagnosis. International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s273. DOI: 10.1016/j.ijrobp.2013.06.711.
- Raldow AC, Chiang VL, Knisely JP, Yu JB. Survival and Intracranial Control of Patients With 5 or More Brain Metastases Treated With Gamma Knife Stereotactic Radiosurgery. American Journal Of Clinical Oncology 2013, 36: 486-490. PMID: 22706180, DOI: 10.1097/coc.0b013e31825494ef.
- Johung KL, Yao X, Li F, Yu JB, Gettinger SN, Goldberg S, Decker RH, Hess JA, Chiang VL, Contessa JN. A Clinical Model for Identifying Radiosensitive Tumor Genotypes in Non–Small Cell Lung Cancer. Clinical Cancer Research 2013, 19: 5523-5532. PMID: 23897899, DOI: 10.1158/1078-0432.ccr-13-0836.
- Guo F, Chiang V, Yu J, Chang B, Bond J, Chen Z, Nath R, Deng J. SU‐E‐T‐389: Treatment Interruptions in Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS): Influence and Compensation. Medical Physics 2013, 40: 294-294. DOI: 10.1118/1.4814823.
- Torres-Reveron J, Tomasiewicz HC, Shetty A, Amankulor NM, Chiang VL. Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery. Journal Of Neuro-Oncology 2013, 113: 495-503. PMID: 23677747, DOI: 10.1007/s11060-013-1142-2.
- Husain ZA, Thibault I, Letourneau D, Ma L, Keller H, Suh J, Chiang V, Chang EL, Rampersaud RK, Perry J, Larson DA, Sahgal A. Stereotactic body radiotherapy: a new paradigm in the management of spinal metastases. CNS Oncology 2013, 2: 259-270. PMID: 25054466, PMCID: PMC6166530, DOI: 10.2217/cns.13.11.
- Flanigan JC, Jilaveanu LB, Chiang VL, Kluger HM. Advances in therapy for melanoma brain metastases. Clinics In Dermatology 2013, 31: 264-281. PMID: 23608446, DOI: 10.1016/j.clindermatol.2012.08.008.
- Sheehan JP, Starke RM, Mathieu D, Young B, Sneed PK, Chiang VL, Lee JY, Kano H, Park KJ, Niranjan A, Kondziolka D, Barnett GH, Rush S, Golfinos JG, Lunsford LD. Gamma Knife radiosurgery for the management of nonfunctioning pituitary adenomas: a multicenter study. Journal Of Neurosurgery 2013, 119: 446-56. PMID: 23621595, DOI: 10.3171/2013.3.jns12766.
- Sperduto PW, Kased N, Roberge D, Chao ST, Shanley R, Luo X, Sneed PK, Suh J, Weil RJ, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer. Journal Of Neuro-Oncology 2013, 112: 467-472. PMID: 23462853, DOI: 10.1007/s11060-013-1083-9.
- Jairam V, Chiang V, Yu JB, Knisely J. Role of stereotactic radiosurgery in patients with more than four brain metastases. CNS Oncology 2013, 2: 181-193. PMID: 24273642, PMCID: PMC3835313, DOI: 10.2217/cns.13.4.
- Grant RA, Whicker M, Lleva R, Knisely JP, Inzucchi SE, Chiang VL. Efficacy and Safety of Higher Dose Stereotactic Radiosurgery for Functional Pituitary Adenomas: A Preliminary Report. World Neurosurgery 2013, 82: 195-201. PMID: 23385448, DOI: 10.1016/j.wneu.2013.01.127.
- Lunsford LD, Chiang V, Adler JR, Sheehan J, Friedman W, Kondziolka D. A recommendation for training in stereotactic radiosurgery for US neurosurgery residents. Journal Of Neurosurgery 2012, 117 Suppl: 2-4. PMID: 23205781, DOI: 10.3171/2012.6.gks12838.
- Nath S, Sheridan A, Rauch P, Contessa J, Yu J, Knisely J, Minja F, Chiang V, Vortmeyer A. TRIC or Tumor: Regrowing Lesions Following Radiosurgery for Brain Metastases — Proposal for a Histopathologic Scale Based on Correlation With Survival. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s297. DOI: 10.1016/j.ijrobp.2012.07.776.
- Johung K, Yu J, Gettinger S, Decker R, Hess J, Chiang V, Contessa J. The Radiosensitivity of Tyrosine Kinase Driven Non-small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s115. DOI: 10.1016/j.ijrobp.2012.07.201.
- Sperduto P, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed P, Chao S, Weil R, Suh J, Bhatt A, Jensen A, Brown P, Shih H, Kirkpatrick J, Gaspar L, Fiveash J, Chiang V, Knisely J, Sperduto C, Lin N, Mehta M. Reply to M.C. Chamberlain et al. Journal Of Clinical Oncology 2012, 30: 3316-3317. DOI: 10.1200/jco.2012.43.0256.
- Knisely JP, Yu JB, Flanigan J, Sznol M, Kluger HM, Chiang VL. Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival. Journal Of Neurosurgery 2012, 117: 227-33. PMID: 22702482, PMCID: PMC6098938, DOI: 10.3171/2012.5.jns111929.
- Patel TR, Knisely JP, Chiang VL. Management of Brain Metastases Surgery, Radiation, or Both? Hematology/Oncology Clinics Of North America 2012, 26: 933-947. PMID: 22794291, DOI: 10.1016/j.hoc.2012.04.008.
- Chitphakdithai N, Chiang VL, Duncan JS. Tracking Metastatic Brain Tumors in Longitudinal Scans via Joint Image Registration and Labeling. Lecture Notes In Computer Science 2012, 7570: 124-136. PMID: 31187098, PMCID: PMC6559745, DOI: 10.1007/978-3-642-33555-6_11.
- Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases. Journal Of Clinical Oncology 2011, 30: 419-425. PMID: 22203767, PMCID: PMC3269967, DOI: 10.1200/jco.2011.38.0527.
- Park H, Yu J, Knisely J, Chiang V. Outcomes Following Gamma Knife for Metastases. 2011 DOI: 10.5772/29841.
- Sperduto P, Chao S, Suh J, Sneed P, Luo X, Roberge D, Bhatt A, Mehta M, Jensen A, Brown P, Shih H, Kirkpatrick J, Gaspar L, Fiveash J, Chiang V, Knisely J, Sperduto C. Reply to Drs. Mulvenna and Holt. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: 1194-1195. DOI: 10.1016/j.ijrobp.2010.09.047.
- Park HS, Chiang VL, Knisely JP, Raldow AC, Yu JB. Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update. Expert Review Of Anticancer Therapy 2011, 11: 1731-1738. PMID: 22050022, DOI: 10.1586/era.11.165.
- Rauch PJ, Park HS, Knisely JP, Chiang VL, Vortmeyer AO. Delayed Radiation-Induced Vasculitic Leukoencephalopathy. International Journal Of Radiation Oncology • Biology • Physics 2011, 83: 369-375. PMID: 22024206, DOI: 10.1016/j.ijrobp.2011.06.1982.
- Klein T, Barbiero F, Bond J, Knisely J, Chiang V, Yu J. Intracranial Hemorrhage in Patients with Metastatic Melanoma Treated by Gamma Knife Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s307. DOI: 10.1016/j.ijrobp.2011.06.1795.
- Knisely J, Chiang V, Kluger H, Flanigan J, Sznol M, Yu J. Outcomes of Melanoma Brain Metastasis Management with Gamma Knife Radiosurgery +/- Ipilimumab. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s302-s303. DOI: 10.1016/j.ijrobp.2011.06.1787.
- Patel TR, McHugh BJ, Bi WL, Minja FJ, Knisely JP, Chiang VL. A Comprehensive Review of MR Imaging Changes following Radiosurgery to 500 Brain Metastases. American Journal Of Neuroradiology 2011, 32: 1885-1892. PMID: 21920854, PMCID: PMC7966021, DOI: 10.3174/ajnr.a2668.
- Patel TR, Ozturk AK, Knisely JP, Chiang VL. Implications of Identifying Additional Cerebral Metastases during Gamma Knife Radiosurgery. International Journal Of Surgical Oncology 2011, 2012: 748284. PMID: 22312543, PMCID: PMC3265271, DOI: 10.1155/2012/748284.
- Flanigan JC, Jilaveanu LB, Faries M, Sznol M, Ariyan S, Yu JB, Knisely JP, Chiang VL, Kluger HM. Melanoma Brain Metastases: Is It Time to Reassess the Bias? Current Problems In Cancer 2011, 35: 200-210. PMID: 21911183, PMCID: PMC3173717, DOI: 10.1016/j.currproblcancer.2011.07.003.
- Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Effect of Tumor Subtype on Survival and the Graded Prognostic Assessment for Patients With Breast Cancer and Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: 2111-2117. PMID: 21497451, PMCID: PMC3172400, DOI: 10.1016/j.ijrobp.2011.02.027.
- Chitphakdithai N, Chiang VL, Duncan JS. Non-rigid Registration of Longitudinal Brain Tumor Treatment MRI. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2011, 2011: 4893-4896. PMID: 22255435, PMCID: PMC3753806, DOI: 10.1109/iembs.2011.6091212.
- Knisely JP, Yamamoto M, Gross CP, Castrucci WA, Jokura H, Chiang VL. Radiosurgery alone for 5 or more brain metastases: expert opinion survey. Journal Of Neurosurgery 2010, 113 Suppl: 84-9. PMID: 21121790, DOI: 10.3171/2010.8.gks10999.
- Castrucci WA, Chiang VL, Hulinsky I, Knisely JP. Biochemical and clinical responses after treatment of a catecholamine‐secreting glomus jugulare tumor with gamma knife radiosurgery. Head & Neck 2010, 32: 1720-1727. PMID: 19787788, DOI: 10.1002/hed.21242.
- Sperduto PW, Chao ST, Sneed PK, Luo X, Suh J, Roberge D, Bhatt A, Jensen AW, Brown PD, Shih H, Kirkpatrick J, Schwer A, Gaspar LE, Fiveash JB, Chiang V, Knisely J, Sperduto CM, Mehta M. Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients. International Journal Of Radiation Oncology • Biology • Physics 2009, 77: 655-661. PMID: 19942357, DOI: 10.1016/j.ijrobp.2009.08.025.
- Redmond A, Chiang V. Postoperative Management in the Neurosurgical Critical Care Unit. 2009, 294-307. DOI: 10.1017/cbo9780511635434.024.
- Deng J, Chen Z, Knisely J, Decker R, Chiang V, Nath R. Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases. IFMBE Proceedings 2009, 25/1: 13-16. DOI: 10.1007/978-3-642-03474-9_4.
- Redmond AJ, DiLuna ML, Hebert R, Moliterno JA, Desai R, Knisely JP, Chiang VL. Gamma Knife surgery for the treatment of melanoma metastases: the effect of intratumoral hemorrhage on survival. Journal Of Neurosurgery 2008, 109 Suppl: 99-105. PMID: 19123895, DOI: 10.3171/jns/2008/109/12/s16.
- Chamberlain D, Yu J, Roberts K, Higgins S, Mani S, Ozturk A, Chiang V, Knisely J. Detection of Occult Brain Metastasis with High Resolution MRI using Double vs. Single Dose Gadolinium. International Journal Of Radiation Oncology • Biology • Physics 2008, 72: s230-s231. DOI: 10.1016/j.ijrobp.2008.06.702.
- Sperduto P, Sneed P, Bhatt A, Schwer A, Fiveash J, Chiang V, Knisely J, Zhu Y, Gaspar L, Mehta M. A Multi-institutional Validation Study of a New Prognostic Index (Graded Prognostic Assessment, GPA) for Patients with Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2008, 72: s51. DOI: 10.1016/j.ijrobp.2008.06.881.
- Knisely J, Gross C, Castrucci W, Chiang V. Survey of Radiosurgery Practitioner Attitudes on the use of Stereotactic Radiosurgery Alone for Oligometastatic Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2008, 72: s241-s242. DOI: 10.1016/j.ijrobp.2008.06.625.
- DiLuna ML, King JT, Knisely JP, Chiang VL. Prognostic factors for survival after stereotactic radiosurgery vary with the number of cerebral metastases. Cancer 2006, 109: 135-145. PMID: 17133440, DOI: 10.1002/cncr.22367.
- Diluna M, King J, Knisely J, Bond J, De Lotbiniere A, Chiang V. Multivariate analysis identifies factors that affect survival after stereotactic radiosurgery for brain metastases. Journal Of Clinical Oncology 2006, 24: 11500-11500. DOI: 10.1200/jco.2006.24.18_suppl.11500.
- DiLuna ML, Johnson MH, Bi WL, Chiang VL, Duncan CC. Sterile ascites from a ventriculoperitoneal shunt: a case report and review of the literature. Child's Nervous System 2006, 22: 1187-1193. PMID: 16541295, DOI: 10.1007/s00381-006-0054-2.
- Johnson MH, Chiang VL, Ross DA. Interventional Neuroradiology Adjuncts and Alternatives in Patients with Head and Neck Vascular Lesions. Neurosurgery Clinics Of North America 2005, 16: 547-560. PMID: 15990044, DOI: 10.1016/j.nec.2005.04.007.
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- Chiang V, Torbey M, Rigamonti D, Williams M. Ventriculopleural shunt obstruction and positive-pressure ventilation. Case report. Journal Of Neurosurgery 2001, 95: 116-8. PMID: 11453379, DOI: 10.3171/jns.2001.95.1.0116.
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- Yale NeurosurgeryYale Physicians Building800 Howard Avenue, Ste Lower LevelNew Haven, CT 06519
Biography
Veronica Chiang MD, a neurosurgeon and director of the Gamma Knife Center at Yale New Haven Hospital, specializes in treating metastatic cancer to the brain using a multidisciplinary approach. She offers both standard neurosurgical surgery as well as cutting edge procedures such as laser thermocoagulation. In addition, she specializes in the use of radiosurgery. This technique allows doctors to transmit radiation directly to tumor cells and avoid radiating healthy brain cells, which can help improve patients’ quality of life after treatment.
Dr. Chiang acknowledges that brain surgery can be a big step for patients and provides as much information about the procedure as possible. “Knowledge helps people deal with how scary it might feel,” she says.
In addition to treating patients, Dr. Chiang conducts research on managing patient care through multidisciplinary approaches, and how technologies like thermocoagulation and radiosurgery can help patients with brain metastases. “The neurological system is one of the last areas where there’s very little known about it. I love learning about it and figuring out how to improve patient’s lives,” she says.
Titles
- Professor of Neurosurgery
- Assistant Dean for Admissions, Medical Education
- Associate Vice Chair of Academic Affairs
- Director, Stereotactic Radiosurgery
- Director, Gamma Knife Center, YNHH
- Director, Stereotactic Radiosurgery Fellowship
Education & Training
- FellowJohns Hopkins University School of Medicine (2000)
- ResidentYale University School of Medicine (2000)
- FellowYale-New Haven Hospital (1994)
- MDUniversity of Western Australia (1992)
- BMedSciUniversity of Western Australia
Additional Information
- First Class Honours (Thesis degree BMedSci): (1991)
- Asthma Foundation of Australia Scholarship: (1990)
- National Health and Medical Research Council of Australia Medical Undergraduate Scholarship: (1988)
- AB of Neurological Surgery, Neurological Surgery (2003, recertified: 2014)
- Kandigian S, Chande S, Dolezal D, Tang T, Wang D, Arnal-Estapé A, Cheok S, McGuone D, Liu Y, Goldberg S, Blondin N, Chiang V, Nguyen D. BSLM-10 MOLECULAR AND HISTOLOGICAL CHARACTERIZATION OF NSCLC PROGRESSION TO LEPTOMENINGEAL METASTASIS WITH COMORBID INTRAPARENCHYMAL DISEASE. Neuro-Oncology Advances 2024, 6: i7-i7. PMCID: PMC11296776, DOI: 10.1093/noajnl/vdae090.020.
- Mahajan A, Goldberg S, Weiss S, Tran T, Singh K, Joshi K, Aboian M, Kluger H, Chiang V. Patterns of brain metastases response to immunotherapy with pembrolizumab. Journal Of Neuro-Oncology 2024, 169: 555-561. PMID: 38963658, DOI: 10.1007/s11060-024-04754-8.
- Robert S, Kiziltug E, Lu B, Arnal-Estape A, Nguyen D, Chiang V. 154 Elucidating the Immune Landscape of Radiation Necrosis Through Single Cell Analysis of Recurrent Brain Lesions in Patients After Stereotactic Radio Surgery. Neurosurgery 2024, 70: 35-36. DOI: 10.1227/neu.0000000000002809_154.
- Nagpal S, Milano M, Chiang V, Soltys S, Brackett A, Halasz L, Garg A, Sahgal A, Ahluwalia M, Tom M, Palmer J, Knisely J, Chao S, Gephart M, Wang T, Lo S, Chang E. Executive summary of the American Radium Society appropriate use criteria for brain metastases in epidermal growth factor receptor mutated-mutated and ALK-fusion non-small cell lung cancer. Neuro-Oncology 2024, 26: 1195-1212. PMID: 38459978, PMCID: PMC11226873, DOI: 10.1093/neuonc/noae041.
- Chiang V, Pugazenthi S, Leidig W, Rodriguez A, Prabhu S, Haskell-Mendoza A, Fecci P, Placantonakis D, Abram S, Lega B, Kim A. Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series. Journal Of Neurosurgery 2024, 141: 642-652. PMID: 38457795, DOI: 10.3171/2023.12.jns231542.
- Strowd R, Chan M, Tatter S, Chiang V, Fecci P, Prabhu S, Hadjipanayis C, Kirkpatrick J, Sun D, Sinicrope K, Mohammadi A, Sevak P, Abram S, Kim A, Leuthardt E, Chao S, Phillips J, Lacroix M, Williams B, Placantonakis D, Silverman J, Baumgartner J, Piccioni D, Laxton A. SURG-32. EFFICACY OF LASER INTERSTITIAL THERMAL THERAPY (LITT) FOR BIOPSY-PROVEN RADIATION NECROSIS IN RADIOGRAPHICALLY RECURRENT BRAIN METASTASES. Neuro-Oncology 2023, 25: v269-v269. PMCID: PMC10640195, DOI: 10.1093/neuonc/noad179.1031.
- Singh C, Theriault B, An Y, Yu J, Knisely J, Shepard M, Wegner R, Warnick R, Peker S, Samanci Y, Trifiletti D, Lee C, Yang H, Bernstein K, Kondziolka D, Tripathi M, Mathieu D, Mantziaris G, Pikis S, Sheehan J, Chiang V. Selected-Lesion SRS as a Novel Strategy in Treatment of Patients with Multiple Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2023, 117: e150-e151. DOI: 10.1016/j.ijrobp.2023.06.971.
- Mange A, Singh C, Theriault B, Hansen J, An Y, Aneja S, Chiang V. Selected-Lesion Stereotactic Radiosurgery in Treatment of Patients with Multiple Brain Metastases: A Single Institution Retrospective Study. International Journal Of Radiation Oncology • Biology • Physics 2023, 117: e135. DOI: 10.1016/j.ijrobp.2023.06.939.
- Kaur M, Petersen G, Jekel L, von Reppert M, Varghese S, de Oliveira Santo I, Avesta A, Aneja S, Omuro A, Chiang V, Aboian M. PACS-Integrated Tools for Peritumoral Edema Volumetrics Provide Additional Information to RANO-BM-Based Assessment of Lung Cancer Brain Metastases after Stereotactic Radiotherapy: A Pilot Study. Cancers 2023, 15: 4822. PMID: 37835516, PMCID: PMC10571649, DOI: 10.3390/cancers15194822.
- Theriault B, Singh C, Yu J, Knisely J, Shepard M, Wegner R, Warnick R, Peker S, Samanci Y, Trifiletti D, Lee C, Yang H, Bernstein K, Kondziolka D, Tripathi M, Mathieu D, Mantziaris G, Pikis S, Sheehan J, Chiang V. Selected-Lesion Stereotactic Radiosurgery (SL-SRS) as a Novel Strategy in the Treatment of Patients With Multiple Brain Metastases. Cureus 2023, 15: e45457. PMID: 37859877, PMCID: PMC10583225, DOI: 10.7759/cureus.45457.
- Kotecha R, Chiang V, Tom M, Nabavizadeh A, Zan E, Peddi S, Sulman E, Siegel B, Huang J, Brem S, Ware M, Kesari S, Parent E, Pope W, Holmes R, Chau A, Teoh E, Chao S, Aboian M. JS09.5.A18F-FLUCICLOVINE PET FOR DETECTION OF RECURRENT BRAIN METASTASES AFTER RADIATION THERAPY: IMAGE INTERPRETATION CRITERIA RESULTS FROM PURSUE, A PROSPECTIVE PHASE 2 TRIAL. Neuro-Oncology 2023, 25: ii12-ii13. PMCID: PMC10489492, DOI: 10.1093/neuonc/noad137.034.
- Kotecha R, Chiang V, Tom M, Nabavizadeh A, Zan E, Peddi S, Sulman E, Siegel B, Huang J, Brem S, Ware M, Kesari S, Parent E, Pope W, Holmes R, Chau A, Teoh E, Chao S, Aboian M. NEIM-05 PURSUE: RESULTS FROM A PROSPECTIVE, PHASE 2B TRIAL TO DEFINE IMAGE INTERPRETATION CRITERIA FOR18F-FLUCICLOVINE-PET FOR DETECTION OF RECURRENT BRAIN METASTASES AFTER RADIATION THERAPY. Neuro-Oncology Advances 2023, 5: iii15-iii15. PMCID: PMC10402431, DOI: 10.1093/noajnl/vdad070.057.
- Lu B, Lucca L, DiStasio M, Liu Y, Pham G, Buitrago-Pocasangre N, Arnal-Estape A, Moliterno J, Chiang V, Omuro A, Hafler D. BSBM-18 SINGLE-CELL PROFILING TUMOR-INFILTRATING IMMUNE CELLS REVEALS CXCL13+ FOLLICULAR HELPER-LIKE CD4+ T CELLS IN HUMAN BRAIN TUMORS. Neuro-Oncology Advances 2023, 5: iii4-iii4. PMCID: PMC10402449, DOI: 10.1093/noajnl/vdad070.014.
- Kotecha R, Chiang V, Tom M, Nabavizadeh A, Zan E, Peddi S, Sulman E, Siegel B, Huang J, Brem S, Ware M, Kesari S, Parent E, Pope W, Holmes R, Chau A, Teoh E, Chao S, Aboian M. Evaluating the diagnostic performance of 18F-fluciclovine for detection of recurrent brain metastases after radiation therapy: Results from a prospective phase 2 trial. Journal Of Clinical Oncology 2023, 41: 2001-2001. DOI: 10.1200/jco.2023.41.16_suppl.2001.
- Corbin Z, Liu Y, Fulbright R, Thaw-Poon S, Baehring J, Blondin N, Kim P, Omuro A, Chiang V, Moliterno J, Omay S, Piepmeier J, Rothman D, de Graaf R, De Feyter H. Imaging metabolism of deuterated glucose in patients with primary brain tumors. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0142.
- Kaur M, Cassinelli G, von Reppert M, Jekel L, Varghese S, Dixe I, Omuro A, Chiang V, Aboian M. Peritumoral edema measurements provide additional information to RANO-BM based assessment of lung cancer brain metastases after Gamma Knife therapy (P10-13.002). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203091.
- Tran T, Caulfield J, Zhang L, Schoenfeld D, Djureinovic D, Chiang V, Oria V, Weiss S, Olino K, Jilaveanu L, Kluger H. Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma. JCI Insight 2023, 8: e157347. PMID: 36821392, PMCID: PMC10132152, DOI: 10.1172/jci.insight.157347.
- Robert S, Lu B, Arnal-Estape A, Nguyen D, Chiang V. 465 Defining the Immune Profile of Radiation Necrosis Through Single-cell Analysis of Intracranial Lesions. Neurosurgery 2023, 69: 97-98. DOI: 10.1227/neu.0000000000002375_465.
- Xu S, Campbell A, Chiang V, Bindra R, Vasquez J, Pashankar F. Use of stereotactic radiosurgery in treatment of brain metastases from pediatric extracranial solid tumors. Pediatric Blood & Cancer 2023, 70: e30303. PMID: 36975152, DOI: 10.1002/pbc.30303.
- Singh R, Bowden G, Mathieu D, Perlow H, Palmer J, Elhamdani S, Shepard M, Liang Y, Nabeel A, Reda W, Tawadros S, Abdelkarim K, El-Shehaby A, Emad R, Elazzazi A, Warnick R, Gozal Y, Daly M, McShane B, Addis-Jackson M, Karthikeyan G, Smith S, Picozzi P, Franzini A, Kaisman-Elbaz T, Yang H, Wei Z, Legarreta A, Hess J, Templeton K, Pikis S, Mantziaris G, Simonova G, Liscak R, Peker S, Samanci Y, Chiang V, Niranjan A, Kersh C, Lee C, Trifiletti D, Lunsford L, Sheehan J. Local Control and Survival Outcomes After Stereotactic Radiosurgery for Brain Metastases From Gastrointestinal Primaries: An International Multicenter Analysis. Neurosurgery 2023, 93: 592-598. PMID: 36942965, DOI: 10.1227/neu.0000000000002456.
- Draeger E, Chen Z, Hansen J, Chiang V, Tien C. Preliminary dosimetric comparison between fixed and rotating source stereotactic radiosurgery systems. Journal Of Applied Clinical Medical Physics 2023, 24: e13907. PMID: 36660774, PMCID: PMC10161057, DOI: 10.1002/acm2.13907.
- Lamsam L, Brigido M, Sivaraju A, Hirsch L, Spencer D, Chiang V, Damisah E. Transfrontal Approach to the Amygdala for Ablation With Laser Interstitial Thermal Therapy: An Epilepsy Case Report. Operative Neurosurgery 2023, 24: e381-e384. PMID: 36715982, PMCID: PMC10158899, DOI: 10.1227/ons.0000000000000576.
- Merkin R, Chiang V, Goldberg S. Management of patients with brain metastases from NSCLC without a genetic driver alteration: upfront radiotherapy or immunotherapy? Therapeutic Advances In Medical Oncology 2023, 15: 17588359231175438. PMID: 37275964, PMCID: PMC10233588, DOI: 10.1177/17588359231175438.
- Chan M, Tatter S, Chiang V, Fecci P, Strowd R, Prabhu S, Hadjipanayis C, Kirkpatrick J, Sun D, Sinicrope K, Mohammadi A, Sevak P, Abram S, Kim A, Leuthardt E, Chao S, Phillips J, Lacroix M, Williams B, Placantonakis D, Silverman J, Baumgartner J, Piccioni D, Laxton A. Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases. Neuro-Oncology Advances 2023, 5: vdad031. PMID: 37114245, PMCID: PMC10129388, DOI: 10.1093/noajnl/vdad031.
- Wandrey N, Gao D, Robin T, Contessa J, Singh C, Chiang V, Li J, Chen A, Wang Y, Sheehan J, Dutta S, Weiss S, Paly J, Rusthoven C. Multicenter analysis of stereotactic radiosurgery for multiple brain metastases from EGFR and ALK driven non-small cell lung cancer. Lung Cancer 2022, 176: 144-148. PMID: 36641932, PMCID: PMC10552603, DOI: 10.1016/j.lungcan.2022.11.019.
- Adua S, Arnal-Estapé A, Zhao M, Qi B, Liu Z, Kravitz C, Hulme H, Strittmatter N, López-Giráldez F, Chande S, Albert A, Melnick M, Hu B, Politi K, Chiang V, Colclough N, Goodwin R, Cross D, Smith P, Nguyen D. Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature Communications 2022, 13: 7690. PMID: 36509758, PMCID: PMC9744876, DOI: 10.1038/s41467-022-34889-z.
- Kowalchuk R, Niranjan A, Hess J, Antonios J, Zhang M, Braunstein S, Ross R, Pikis S, Deibert C, Lee C, Yang H, Langlois A, Mathieu D, Peker S, Samanci Y, Rusthoven C, Chiang V, Wei Z, Lunsford L, Trifiletti D, Sheehan J. Stereotactic radiosurgery and local control of brain metastases from triple-negative breast cancer. Journal Of Neurosurgery 2022, 138: 1608-1614. PMID: 36433878, DOI: 10.3171/2022.10.jns221900.
- Robert S, Lu B, Kiziltug E, Estape A, Nguyen D, Chiang V. IMMU-01. DEFINING THE IMMUNE PROFILE OF RADIATION NECROSIS THROUGH SINGLE-CELL ANALYSIS OF INTRACRANIAL LESIONS. Neuro-Oncology 2022, 24: vii131-vii131. DOI: 10.1093/neuonc/noac209.499.
- de Groot J, Kim A, Prabhu S, Rao G, Laxton A, Fecci P, O'Brien B, Sloan A, Chiang V, Tatter S, Mohammadi A, Placantonakis D, Strowd R, Chen C, Hadjipanayis C, Khasraw M, Sun D, Piccioni D, Sinicrope K, Campian J, Kurz S, Williams B, Smith K, Tovar-Spinoza Z, Leuthardt E. SURG-23. EFFICACY OF LASER INTERSTITIAL THERMAL THERAPY (LITT) FOR NEWLY DIAGNOSED AND RECURRENT IDH WILD-TYPE GLIOBLASTOMA. Neuro-Oncology 2022, 24: vii256-vii257. PMCID: PMC9660753, DOI: 10.1093/neuonc/noac209.989.
- Kaur M, Petersen G, von Reppert M, Jekel L, de Santo I, Varghese S, Chiang V, Aboian M. NIMG-04. LONGITUDINAL TRACKING OF PERITUMORAL EDEMA VOLUME USING PACS-INTEGRATED TOOLS PROVIDES CRITICAL INFORMATION IN TREATMENT ASSESSMENT OF NSCLC BRAIN METASTASES AFTER RADIOSURGERY. Neuro-Oncology 2022, 24: vii162-vii162. PMCID: PMC9661156, DOI: 10.1093/neuonc/noac209.624.
- Kaur M, Varghese S, Jekel L, Tillmanns N, Merkaj S, Bousabarah K, Lin M, Bhawnani J, Chiang V, Aboian M. NIMG-07. APPLYING A GLIOMA-TRAINED DEEP LEARNING AUTO-SEGMENTATION TOOL ON BM PRE- AND POST-RADIOSURGERY. Neuro-Oncology 2022, 24: vii162-vii163. PMCID: PMC9660643, DOI: 10.1093/neuonc/noac209.626.
- Jekel L, Bousabarah K, Lin M, Merkaj S, Kaur M, Avesta A, Aneja S, Omuro A, Chiang V, Scheffler B, Aboian M. NIMG-02. PACS-INTEGRATED AUTO-SEGMENTATION WORKFLOW FOR BRAIN METASTASES USING NNU-NET. Neuro-Oncology 2022, 24: vii162-vii162. PMCID: PMC9661012, DOI: 10.1093/neuonc/noac209.622.
- Fomchenko EI, Leelatian N, Darbinyan A, Huttner AJ, Chiang VL. Histological changes associated with laser interstitial thermal therapy for radiation necrosis: illustrative cases. Journal Of Neurosurgery Case Lessons 2022, 4: case21373. PMID: 35855352, PMCID: PMC9257400, DOI: 10.3171/case21373.
- Aizer AA, Lamba N, Ahluwalia MS, Aldape K, Boire A, Brastianos PK, Brown PD, Camidge DR, Chiang VL, Davies MA, Hu LS, Huang RY, Kaufmann T, Kumthekar P, Lam K, Lee EQ, Lin NU, Mehta M, Parsons M, Reardon DA, Sheehan J, Soffietti R, Tawbi H, Weller M, Wen PY. Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions. Neuro-Oncology 2022, 24: 1613-1646. PMID: 35762249, PMCID: PMC9527527, DOI: 10.1093/neuonc/noac118.
- Tom MC, Milano MT, Chao ST, Soltys SG, Knisely JPS, Sahgal A, Nagpal S, Lo SS, Jabbari S, Wang TJC, Ahluwalia MS, Simonson M, Palmer JD, Gephart MH, Halasz LM, Garg AK, Chiang VLS, Chang EL. Executive summary of American Radium Society’s appropriate use criteria for the postoperative management of lower grade gliomas. Radiotherapy And Oncology 2022, 170: 79-88. PMID: 35367527, DOI: 10.1016/j.radonc.2022.03.018.
- Shahsavari N, Ahmad M, Sekar V, Meola A, Hancock SL, Chang SD, Chiang VL. Synchronous glioblastoma and brain metastases: illustrative case. Journal Of Neurosurgery Case Lessons 2022, 3: case21714. PMID: 36273867, PMCID: PMC9379681, DOI: 10.3171/case21714.
- Sperduto PW, De B, Li J, Carpenter D, Kirkpatrick J, Milligan M, Shih HA, Kutuk T, Kotecha R, Higaki H, Otsuka M, Aoyama H, Bourgoin M, Roberge D, Dajani S, Sachdev S, Gainey J, Buatti JM, Breen W, Brown PD, Ni L, Braunstein S, Gallitto M, Wang TJC, Shanley R, Lou E, Shiao J, Gaspar LE, Tanabe S, Nakano T, An Y, Chiang V, Zeng L, Soliman H, Elhalawani H, Cagney D, Thomas E, Boggs DH, Ahluwalia MS, Mehta MP. Graded Prognostic Assessment (GPA) for Patients With Lung Cancer and Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA Including the Effect of Programmed Death Ligand 1 and Other Prognostic Factors. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: 60-74. PMID: 35331827, PMCID: PMC9378572, DOI: 10.1016/j.ijrobp.2022.03.020.
- Jekel L, Brim WR, von Reppert M, Staib L, Petersen G, Merkaj S, Subramanian H, Zeevi T, Payabvash S, Bousabarah K, Lin M, Cui J, Brackett A, Mahajan A, Omuro A, Johnson MH, Chiang VL, Malhotra A, Scheffler B, Aboian MS. Machine Learning Applications for Differentiation of Glioma from Brain Metastasis—A Systematic Review. Cancers 2022, 14: 1369. PMID: 35326526, PMCID: PMC8946855, DOI: 10.3390/cancers14061369.
- Cheok S, Arnal-Estape A, Wei W, Nguyen D, Chiang V. 513 Surveilling Cerebrospinal Fluid Protein Biomarkers in Brain Metastasis. Neurosurgery 2022, 68: 129-129. DOI: 10.1227/neu.0000000000001880_513.
- Alvi MA, Asher AL, Michalopoulos GD, Grills IS, Warnick RE, McInerney J, Chiang VL, Attia A, Timmerman R, Chang E, Kavanagh BD, Andrews DW, Walter K, Bydon M, Sheehan JP. Factors associated with progression and mortality among patients undergoing stereotactic radiosurgery for intracranial metastasis: results from a national real-world registry. Journal Of Neurosurgery 2022, 137: 985-998. PMID: 35171833, DOI: 10.3171/2021.10.jns211410.
- Petersen G, Bousabarah K, Verma T, von Reppert M, Jekel L, Gordem A, Jang B, Merkaj S, Fadel S, Owens R, Omuro A, Chiang V, Ikuta I, Lin M, Aboian MS. Real-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery. Neuro-Oncology Advances 2022, 4: vdac116. PMID: 36043121, PMCID: PMC9412827, DOI: 10.1093/noajnl/vdac116.
- Grabowski MM, Srinivasan ES, Vaios EJ, Sankey EW, Otvos B, Krivosheya D, Scott A, Olufawo M, Ma J, Fomchenko EI, Herndon JE, Kim AH, Chiang VL, Chen CC, Leuthardt EC, Barnett GH, Kirkpatrick JP, Mohammadi AM, Fecci PE. Combination laser interstitial thermal therapy plus stereotactic radiotherapy increases time to progression for biopsy-proven recurrent brain metastases. Neuro-Oncology Advances 2022, 4: vdac086. PMID: 35795470, PMCID: PMC9248774, DOI: 10.1093/noajnl/vdac086.
- de Groot JF, Kim AH, Prabhu S, Rao G, Laxton AW, Fecci PE, O’Brien B, Sloan A, Chiang V, Tatter SB, Mohammadi AM, Placantonakis DG, Strowd RE, Chen C, Hadjipanayis C, Khasraw M, Sun D, Piccioni D, Sinicrope KD, Campian JL, Kurz SC, Williams B, Smith K, Tovar-Spinoza Z, Leuthardt EC. Efficacy of laser interstitial thermal therapy (LITT) for newly diagnosed and recurrent IDH wild-type glioblastoma. Neuro-Oncology Advances 2022, 4: vdac040. PMID: 35611270, PMCID: PMC9122789, DOI: 10.1093/noajnl/vdac040.
- Cifarelli C, Vargo J, Fang W, Liscak R, Guseynova K, Warnick R, Lee C, Yang H, Borghei-Razavi H, Maiti T, Siddiqui Z, Yuan J, Grills I, Mathieu D, Touchette C, Cordeiro D, Chiang V, Hess J, Tien C, Faramand A, Kano H, Barnett G, Sheehan J, Lunsford L. Role of Gamma Knife Radiosurgery in Small Cell Lung Cancer: A Multi-Institutional Retrospective Study of the International Radiosurgery Research Foundation (IRRF). Neurosurgery 2021, 89: s20-s20. DOI: 10.1093/neuros/nyz428_s020.
- Kim A, Tatter S, Rao G, Prabhu S, Chen C, Fecci P, Chiang V, Smith K, Williams B, Mohammadi A, Judy K, Sloan A, Tovar-Spinoza Z, Baumgartner J, Hadjipanayis C, Leuthardt E. Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (LAANTERN): 12-Month Outcomes and Quality of Life After Brain Tumor Ablation. Neurosurgery 2021, 89: s16-s16. PMCID: PMC8600280, DOI: 10.1093/neuros/nyaa071_s016.
- Cheok S, Hansen J, Chiang V. Recognition and Management of Adverse Radiation Effects. 2021, 391-404. DOI: 10.1201/9781003167464-36.
- Lu BY, Gupta R, Aguirre-Ducler A, Gianino N, Wyatt H, Ribeiro M, Chiang VL, Contessa JN, Adeniran AJ, Jilaveanu LB, Kluger HM, Schalper KA, Goldberg SB. Spatially resolved analysis of the T cell immune contexture in lung cancer-associated brain metastases. Journal For ImmunoTherapy Of Cancer 2021, 9: e002684. PMID: 34670827, PMCID: PMC8529973, DOI: 10.1136/jitc-2021-002684.
- Kowalchuk RO, Niranjan A, Lee CC, Yang HC, Liscak R, Guseynova K, Tripathi M, Kumar N, Peker S, Samanci Y, Hess J, Chiang V, Iorio-Morin C, Mathieu D, Pikis S, Wei Z, Lunsford LD, Trifiletti DM, Sheehan JP. Reirradiation With Stereotactic Radiosurgery After Local or Marginal Recurrence of Brain Metastases From Previous Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2021, 112: 726-734. PMID: 34644606, DOI: 10.1016/j.ijrobp.2021.10.008.
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- Contessa JN, Johung KL, Goldberg S, Chiang VL. Reply to M.S. Copur et al and to M.C. Chamberlain. Journal Of Clinical Oncology 2016, 34: 2316-2317. PMID: 27114599, DOI: 10.1200/jco.2016.67.2816.
- Cao Y, Nylander A, Ramanan S, Goods BA, Ponath G, Zabad R, Chiang VL, Vortmeyer AO, Hafler DA, Pitt D. CNS demyelination and enhanced myelin-reactive responses after ipilimumab treatment. Neurology 2016, 86: 1553-1556. PMID: 26984943, PMCID: PMC5573201, DOI: 10.1212/wnl.0000000000002594.
- Cohen JV, Alomari AK, Vortmeyer AO, Jilaveanu LB, Goldberg SB, Mahajan A, Chiang VL, Kluger HM. Melanoma Brain Metastasis Pseudoprogression after Pembrolizumab Treatment. Cancer Immunology Research 2016, 4: 179-182. PMID: 26701266, PMCID: PMC4881844, DOI: 10.1158/2326-6066.cir-15-0160.
- Magnuson WJ, Yeung JT, Guillod PD, Gettinger SN, Yu JB, Chiang VL. Impact of Deferring Radiation Therapy in Patients With Epidermal Growth Factor Receptor–Mutant Non-Small Cell Lung Cancer Who Develop Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2016, 95: 673-679. PMID: 27034176, DOI: 10.1016/j.ijrobp.2016.01.037.
- Zohrabian VM, Husain ZA, Laurans MS, Chiang VL, Mahajan A, Johnson MH. Practice Building: Achieving Growth Through Computed Tomographic Myelography–Based Stereotactic Body Radiation Therapy for Spinal Metastases. Current Problems In Diagnostic Radiology 2016, 45: 324-329. PMID: 26920633, DOI: 10.1067/j.cpradiol.2016.01.004.
- Qian J, Yu J, Gettinger S, Chiang V. Ceritinib enables stereotactic radiosurgery to a previously untreatable symptomatic brain metastasis in a patient with ALK rearranged non-small cell lung cancer. Cancer Treatment And Research Communications 2016, 6: 17-19. DOI: 10.1016/j.ctrc.2016.02.002.
- Colaco RJ, Yu JB, Bond JS, Bindra RS, Contessa JN, Knisely JPS, Chiang VL. A contemporary dose selection algorithm for stereotactic radiosurgery in the treatment of brain metastases - An initial report. Journal Of Radiosurgery And SBRT 2016, 4: 43-52. PMID: 29296425, PMCID: PMC5658834.
- Taylor BF, Knisely JP, Qian JM, Yu JB, Chiang VL. Predicting treatment related imaging changes (TRICs) after radiosurgery for brain metastases using treatment dose and conformality metrics. Journal Of Radiosurgery And SBRT 2016, 4: 53-60. PMID: 29296426, PMCID: PMC5658837.
- Rutter CE, Johung KL, Yao X, Lu AY, Jilaveanu LB, Yu JB, Contessa JN, Kluger HM, Chiang VLS, Bindra RS. Demonstration of differential radiosensitivity based upon mutation profile in metastatic melanoma treated with stereotactic radiosurgery. Journal Of Radiosurgery And SBRT 2016, 4: 97-106. PMID: 29296434, PMCID: PMC5658871.
- Chiang VL, Knisely JP. Top 25 cited articles on Gamma Knife surgery published since 2005 in journals of the American Association of Neurological Surgeons. Journal Of Neurosurgery 2015, 123 Spec Suppl: 1-2. PMID: 26620469, DOI: 10.3171/2015.12.jnsleksellintro.
- Mohammadi A, Chiang V, Beaumont T, Elson P, Barnett G, Leuthardt E. SURG-20A MULTICENTER SURVIVAL ANALYSIS OF UPFRONT LASER-ABLATION FOR TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA. Neuro-Oncology 2015, 17: v218-v218. PMCID: PMC4639277, DOI: 10.1093/neuonc/nov235.20.
- Colaco RJ, Martin P, Kluger HM, Yu JB, Chiang VL. Does immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases? Journal Of Neurosurgery 2015, 125: 17-23. PMID: 26544782, DOI: 10.3171/2015.6.jns142763.
- Park H, Wang E, Rutter C, Corso C, Chiang V, Yu J. Shifts in Stereotactic Radiosurgery Platform Utilization for Brain Metastases in the United States. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e62. DOI: 10.1016/j.ijrobp.2015.07.701.
- Jairam V, Chiang V, Yu J. Prognostic Factors for Seizures After First Radiosurgical Treatment in Patients With Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e100. DOI: 10.1016/j.ijrobp.2015.07.802.
- Park H, Colaco R, Laurans M, Chiang V, Yu J, Husain Z. Spine Stereotactic Body Radiation Therapy Outcomes in Patients With Concurrent Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e62. DOI: 10.1016/j.ijrobp.2015.07.702.
- Park HS, Wang EH, Rutter CE, Corso CD, Chiang VL, Yu JB. Changing practice patterns of Gamma Knife versus linear accelerator-based stereotactic radiosurgery for brain metastases in the US. Journal Of Neurosurgery 2015, 124: 1018-24. PMID: 26473783, DOI: 10.3171/2015.4.jns1573.
- Johung KL, Yeh N, Desai NB, Williams TM, Lautenschlaeger T, Arvold ND, Ning MS, Attia A, Lovly CM, Goldberg S, Beal K, Yu JB, Kavanagh BD, Chiang VL, Camidge DR, Contessa JN. Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastasis. Journal Of Clinical Oncology 2015, 34: 123-129. PMID: 26438117, PMCID: PMC5070549, DOI: 10.1200/jco.2015.62.0138.
- Sheehan JP, Cohen-Inbar O, Ruangkanchanasetr R, Bulent Omay S, Hess J, Chiang V, Iorio-Morin C, Alonso-Basanta M, Mathieu D, Grills IS, Lee JY, Lee CC, Dade Lunsford L. Post-radiosurgical edema associated with parasagittal and parafalcine meningiomas: a multicenter study. Journal Of Neuro-Oncology 2015, 125: 317-324. PMID: 26329323, DOI: 10.1007/s11060-015-1911-1.
- Goldberg SB, Contessa JN, Omay SB, Chiang V. Lung Cancer Brain Metastases. The Cancer Journal 2015, 21: 398-403. PMID: 26389765, DOI: 10.1097/ppo.0000000000000146.
- Yushak ML, Chiang VL, Kluger HM. Clinical trials in melanoma patients with brain metastases. Pigment Cell & Melanoma Research 2015, 28: 741-743. PMID: 26205399, PMCID: PMC4834841, DOI: 10.1111/pcmr.12401.
- Kluger HM, Zito CR, Barr ML, Baine MK, Chiang VL, Sznol M, Rimm DL, Chen L, Jilaveanu LB. Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites. Clinical Cancer Research 2015, 21: 3052-3060. PMID: 25788491, PMCID: PMC4490112, DOI: 10.1158/1078-0432.ccr-14-3073.
- Chiang V. Surgery in neuro-oncolgy with a focus on stereotactic radiosurgery. CNS Oncology 2015, 4: 199-201. PMID: 26118857, PMCID: PMC6088336, DOI: 10.2217/cns.15.18.
- Colaco R, Martin P, Chiang V. Evolution of multidisciplinary brain metastasis management: case study and literature review. The Yale Journal Of Biology And Medicine 2015, 88: 157-65. PMID: 26029014, PMCID: PMC4445437.
- Kluger H, Goldberg S, Sznol M, Tsiouris J, Vortmeyer A, Jilaveanu L, Ralabate A, Rivera A, Burke M, Hegbe U, Cohen J, Yao X, Speaker S, Madura M, Knapp-Perry E, Mahajan A, Chiang V. Safety and activity of pembrolizumab in melanoma patients with untreated brain metastases. Journal Of Clinical Oncology 2015, 33: 9009-9009. DOI: 10.1200/jco.2015.33.15_suppl.9009.
- Goldberg S, Gettinger S, Mahajan A, Herbst R, Chiang A, Tsiouris A, Vortmeyer A, Jilaveanu L, Speaker S, Madura M, Rowen E, Gerrish H, Knapp-Perry E, Yao X, Chiang V, Kluger H. Activity and safety of pembrolizumab in patients with metastatic non-small cell lung cancer with untreated brain metastases. Journal Of Clinical Oncology 2015, 33: 8035-8035. DOI: 10.1200/jco.2015.33.15_suppl.8035.
- Sheehan JP, Kano H, Xu Z, Chiang V, Mathieu D, Chao S, Akpinar B, Lee JY, Yu JB, Hess J, Wu HM, Chung WY, Pierce J, Missios S, Kondziolka D, Alonso-Basanta M, Barnett GH, Lunsford LD. Gamma Knife radiosurgery for facial nerve schwannomas: a multicenter study. Journal Of Neurosurgery 2015, 123: 387-94. PMID: 25955875, DOI: 10.3171/2014.11.jns141160.
- Sheehan JP, Starke RM, Kano H, Barnett GH, Mathieu D, Chiang V, Yu JB, Hess J, McBride HL, Honea N, Nakaji P, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD. Gamma Knife radiosurgery for posterior fossa meningiomas: a multicenter study. Journal Of Neurosurgery 2015, 122: 1479-89. PMID: 25859812, DOI: 10.3171/2014.10.jns14139.
- Campbell AM, Glover J, Chiang VL, Gerrard J, Yu JB. Gamma knife stereotactic radiosurgical thalamotomy for intractable tremor: A systematic review of the literature. Radiotherapy And Oncology 2015, 114: 296-301. PMID: 25690750, DOI: 10.1016/j.radonc.2015.01.013.
- Jairam V, Chiang VL, Bond J, Yu JB. Equivalent whole brain dose for patients undergoing gamma knife for multiple lesions. Journal Of Radiosurgery And SBRT 2015, 3: 187-191. PMID: 29296401, PMCID: PMC5746333.
- Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. BM-10SYSTEMIC TREATMENT AND RADIATION NECROSIS FOLLOWING GKSRS IN THE TREATMENT OF BRAIN METASTASES. Neuro-Oncology 2014, 16: v34-v34. PMCID: PMC4217910, DOI: 10.1093/neuonc/nou240.10.
- Ding D, Starke RM, Kano H, Nakaji P, Barnett GH, Mathieu D, Chiang V, Omay SB, Hess J, McBride HL, Honea N, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD, Sheehan JP. Gamma Knife Radiosurgery for Cerebellopontine Angle Meningiomas: A Multicenter Study. Neurosurgery 2014, 75: 398-408. PMID: 24991710, DOI: 10.1227/neu.0000000000000480.
- Colaco R, Yu J, Bond J, Bindra R, Contessa J, Knisely J, Chiang V. Dose Selection Algorithm for Gamma Knife Treatment of Cerebral Metastases: Preliminary Results. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s310-s311. DOI: 10.1016/j.ijrobp.2014.05.1036.
- Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. Systemic Treatment and Radiation Necrosis Following Gamma Knife Radiosurgery in the Treatment of Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s310. DOI: 10.1016/j.ijrobp.2014.05.1035.
- Starke R, Kano H, Ding D, Nakaji P, Barnett GH, Mathieu D, Chiang V, Yu JB, Hess J, McBride HL, Honea N, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD, Sheehan JP. Stereotactic radiosurgery of petroclival meningiomas: a multicenter study. Journal Of Neuro-Oncology 2014, 119: 169-176. PMID: 24821284, DOI: 10.1007/s11060-014-1470-x.
- Sheehan JP, Starke RM, Kano H, Kaufmann AM, Mathieu D, Zeiler FA, West M, Chao ST, Varma G, Chiang VL, Yu JB, McBride HL, Nakaji P, Youssef E, Honea N, Rush S, Kondziolka D, Lee JY, Bailey RL, Kunwar S, Petti P, Lunsford LD. Gamma Knife radiosurgery for sellar and parasellar meningiomas: a multicenter study. Journal Of Neurosurgery 2014, 120: 1268-77. PMID: 24678777, DOI: 10.3171/2014.2.jns13139.
- Nath SK, Sheridan AD, Rauch PJ, Yu JB, Minja FJ, Vortmeyer AO, Chiang VL. Significance of histology in determining management of lesions regrowing after radiosurgery. Journal Of Neuro-Oncology 2014, 117: 303-310. PMID: 24504499, DOI: 10.1007/s11060-014-1389-2.
- Patel T, Chiang V. Laser interstitial thermal therapy for treatment of post-radiosurgery tumor recurrence and radiation necrosis. Photonics And Lasers In Medicine 2014, 3: 95-105. DOI: 10.1515/plm-2013-0057.
- Wang C, Roberts KB, Bindra RS, Chiang VL, Yu JB. Delayed Cerebral Vasculopathy Following Cranial Radiation Therapy for Pediatric Tumors. Pediatric Neurology 2014, 50: 549-556. PMID: 24739378, DOI: 10.1016/j.pediatrneurol.2013.09.018.
- Alomari A, Rauch PJ, Orsaria M, Minja FJ, Chiang VL, Vortmeyer AO. Radiologic and histologic consequences of radiosurgery for brain tumors. Journal Of Neuro-Oncology 2014, 117: 33-42. PMID: 24442402, DOI: 10.1007/s11060-014-1359-8.
- Chiang V, Awad I. Mass Effect. 2014, 1007-1008. DOI: 10.1016/b978-0-12-385157-4.00765-x.
- Kuzmik GA, Michaelides EM, Chiang VL, Nonaka Y, Fukushima T, Vortmeyer AO, Bulsara KR. Rapidly Progressive Epithelioid Malignant Peripheral Nerve Sheath Tumor of the Vestibular Nerve. Otology & Neurotology 2013, 34: 1739-1742. PMID: 23988994, DOI: 10.1097/mao.0b013e31829ab8be.
- Patel TR, Chiang VL. Secondary Neoplasms After Stereotactic Radiosurgery. World Neurosurgery 2013, 81: 594-599. PMID: 24148883, DOI: 10.1016/j.wneu.2013.10.043.
- Rutter C, Giesen E, Yu J, Bindra R, Kluger H, Chiang V. Influence of BRAF and NRAS Mutations on Distant Intracranial Recurrence and Survival in Metastatic Melanoma Following Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s275. DOI: 10.1016/j.ijrobp.2013.06.717.
- Prognostic Factors in Patients With Brain Metastases at Initial Non-Small Cell Lung Cancer DiagnosisRutter C, Mancini B, Yu J, Chiang V, Bindra R. Prognostic Factors in Patients With Brain Metastases at Initial Non-Small Cell Lung Cancer Diagnosis. International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s273. DOI: 10.1016/j.ijrobp.2013.06.711.
- Raldow AC, Chiang VL, Knisely JP, Yu JB. Survival and Intracranial Control of Patients With 5 or More Brain Metastases Treated With Gamma Knife Stereotactic Radiosurgery. American Journal Of Clinical Oncology 2013, 36: 486-490. PMID: 22706180, DOI: 10.1097/coc.0b013e31825494ef.
- Johung KL, Yao X, Li F, Yu JB, Gettinger SN, Goldberg S, Decker RH, Hess JA, Chiang VL, Contessa JN. A Clinical Model for Identifying Radiosensitive Tumor Genotypes in Non–Small Cell Lung Cancer. Clinical Cancer Research 2013, 19: 5523-5532. PMID: 23897899, DOI: 10.1158/1078-0432.ccr-13-0836.
- Guo F, Chiang V, Yu J, Chang B, Bond J, Chen Z, Nath R, Deng J. SU‐E‐T‐389: Treatment Interruptions in Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS): Influence and Compensation. Medical Physics 2013, 40: 294-294. DOI: 10.1118/1.4814823.
- Torres-Reveron J, Tomasiewicz HC, Shetty A, Amankulor NM, Chiang VL. Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery. Journal Of Neuro-Oncology 2013, 113: 495-503. PMID: 23677747, DOI: 10.1007/s11060-013-1142-2.
- Husain ZA, Thibault I, Letourneau D, Ma L, Keller H, Suh J, Chiang V, Chang EL, Rampersaud RK, Perry J, Larson DA, Sahgal A. Stereotactic body radiotherapy: a new paradigm in the management of spinal metastases. CNS Oncology 2013, 2: 259-270. PMID: 25054466, PMCID: PMC6166530, DOI: 10.2217/cns.13.11.
- Flanigan JC, Jilaveanu LB, Chiang VL, Kluger HM. Advances in therapy for melanoma brain metastases. Clinics In Dermatology 2013, 31: 264-281. PMID: 23608446, DOI: 10.1016/j.clindermatol.2012.08.008.
- Sheehan JP, Starke RM, Mathieu D, Young B, Sneed PK, Chiang VL, Lee JY, Kano H, Park KJ, Niranjan A, Kondziolka D, Barnett GH, Rush S, Golfinos JG, Lunsford LD. Gamma Knife radiosurgery for the management of nonfunctioning pituitary adenomas: a multicenter study. Journal Of Neurosurgery 2013, 119: 446-56. PMID: 23621595, DOI: 10.3171/2013.3.jns12766.
- Sperduto PW, Kased N, Roberge D, Chao ST, Shanley R, Luo X, Sneed PK, Suh J, Weil RJ, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer. Journal Of Neuro-Oncology 2013, 112: 467-472. PMID: 23462853, DOI: 10.1007/s11060-013-1083-9.
- Jairam V, Chiang V, Yu JB, Knisely J. Role of stereotactic radiosurgery in patients with more than four brain metastases. CNS Oncology 2013, 2: 181-193. PMID: 24273642, PMCID: PMC3835313, DOI: 10.2217/cns.13.4.
- Grant RA, Whicker M, Lleva R, Knisely JP, Inzucchi SE, Chiang VL. Efficacy and Safety of Higher Dose Stereotactic Radiosurgery for Functional Pituitary Adenomas: A Preliminary Report. World Neurosurgery 2013, 82: 195-201. PMID: 23385448, DOI: 10.1016/j.wneu.2013.01.127.
- Lunsford LD, Chiang V, Adler JR, Sheehan J, Friedman W, Kondziolka D. A recommendation for training in stereotactic radiosurgery for US neurosurgery residents. Journal Of Neurosurgery 2012, 117 Suppl: 2-4. PMID: 23205781, DOI: 10.3171/2012.6.gks12838.
- Nath S, Sheridan A, Rauch P, Contessa J, Yu J, Knisely J, Minja F, Chiang V, Vortmeyer A. TRIC or Tumor: Regrowing Lesions Following Radiosurgery for Brain Metastases — Proposal for a Histopathologic Scale Based on Correlation With Survival. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s297. DOI: 10.1016/j.ijrobp.2012.07.776.
- Johung K, Yu J, Gettinger S, Decker R, Hess J, Chiang V, Contessa J. The Radiosensitivity of Tyrosine Kinase Driven Non-small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s115. DOI: 10.1016/j.ijrobp.2012.07.201.
- Sperduto P, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed P, Chao S, Weil R, Suh J, Bhatt A, Jensen A, Brown P, Shih H, Kirkpatrick J, Gaspar L, Fiveash J, Chiang V, Knisely J, Sperduto C, Lin N, Mehta M. Reply to M.C. Chamberlain et al. Journal Of Clinical Oncology 2012, 30: 3316-3317. DOI: 10.1200/jco.2012.43.0256.
- Knisely JP, Yu JB, Flanigan J, Sznol M, Kluger HM, Chiang VL. Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival. Journal Of Neurosurgery 2012, 117: 227-33. PMID: 22702482, PMCID: PMC6098938, DOI: 10.3171/2012.5.jns111929.
- Patel TR, Knisely JP, Chiang VL. Management of Brain Metastases Surgery, Radiation, or Both? Hematology/Oncology Clinics Of North America 2012, 26: 933-947. PMID: 22794291, DOI: 10.1016/j.hoc.2012.04.008.
- Chitphakdithai N, Chiang VL, Duncan JS. Tracking Metastatic Brain Tumors in Longitudinal Scans via Joint Image Registration and Labeling. Lecture Notes In Computer Science 2012, 7570: 124-136. PMID: 31187098, PMCID: PMC6559745, DOI: 10.1007/978-3-642-33555-6_11.
- Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases. Journal Of Clinical Oncology 2011, 30: 419-425. PMID: 22203767, PMCID: PMC3269967, DOI: 10.1200/jco.2011.38.0527.
- Park H, Yu J, Knisely J, Chiang V. Outcomes Following Gamma Knife for Metastases. 2011 DOI: 10.5772/29841.
- Sperduto P, Chao S, Suh J, Sneed P, Luo X, Roberge D, Bhatt A, Mehta M, Jensen A, Brown P, Shih H, Kirkpatrick J, Gaspar L, Fiveash J, Chiang V, Knisely J, Sperduto C. Reply to Drs. Mulvenna and Holt. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: 1194-1195. DOI: 10.1016/j.ijrobp.2010.09.047.
- Park HS, Chiang VL, Knisely JP, Raldow AC, Yu JB. Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update. Expert Review Of Anticancer Therapy 2011, 11: 1731-1738. PMID: 22050022, DOI: 10.1586/era.11.165.
- Rauch PJ, Park HS, Knisely JP, Chiang VL, Vortmeyer AO. Delayed Radiation-Induced Vasculitic Leukoencephalopathy. International Journal Of Radiation Oncology • Biology • Physics 2011, 83: 369-375. PMID: 22024206, DOI: 10.1016/j.ijrobp.2011.06.1982.
- Klein T, Barbiero F, Bond J, Knisely J, Chiang V, Yu J. Intracranial Hemorrhage in Patients with Metastatic Melanoma Treated by Gamma Knife Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s307. DOI: 10.1016/j.ijrobp.2011.06.1795.
- Knisely J, Chiang V, Kluger H, Flanigan J, Sznol M, Yu J. Outcomes of Melanoma Brain Metastasis Management with Gamma Knife Radiosurgery +/- Ipilimumab. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s302-s303. DOI: 10.1016/j.ijrobp.2011.06.1787.
- Patel TR, McHugh BJ, Bi WL, Minja FJ, Knisely JP, Chiang VL. A Comprehensive Review of MR Imaging Changes following Radiosurgery to 500 Brain Metastases. American Journal Of Neuroradiology 2011, 32: 1885-1892. PMID: 21920854, PMCID: PMC7966021, DOI: 10.3174/ajnr.a2668.
- Patel TR, Ozturk AK, Knisely JP, Chiang VL. Implications of Identifying Additional Cerebral Metastases during Gamma Knife Radiosurgery. International Journal Of Surgical Oncology 2011, 2012: 748284. PMID: 22312543, PMCID: PMC3265271, DOI: 10.1155/2012/748284.
- Flanigan JC, Jilaveanu LB, Faries M, Sznol M, Ariyan S, Yu JB, Knisely JP, Chiang VL, Kluger HM. Melanoma Brain Metastases: Is It Time to Reassess the Bias? Current Problems In Cancer 2011, 35: 200-210. PMID: 21911183, PMCID: PMC3173717, DOI: 10.1016/j.currproblcancer.2011.07.003.
- Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Effect of Tumor Subtype on Survival and the Graded Prognostic Assessment for Patients With Breast Cancer and Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: 2111-2117. PMID: 21497451, PMCID: PMC3172400, DOI: 10.1016/j.ijrobp.2011.02.027.
- Chitphakdithai N, Chiang VL, Duncan JS. Non-rigid Registration of Longitudinal Brain Tumor Treatment MRI. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2011, 2011: 4893-4896. PMID: 22255435, PMCID: PMC3753806, DOI: 10.1109/iembs.2011.6091212.
- Knisely JP, Yamamoto M, Gross CP, Castrucci WA, Jokura H, Chiang VL. Radiosurgery alone for 5 or more brain metastases: expert opinion survey. Journal Of Neurosurgery 2010, 113 Suppl: 84-9. PMID: 21121790, DOI: 10.3171/2010.8.gks10999.
- Castrucci WA, Chiang VL, Hulinsky I, Knisely JP. Biochemical and clinical responses after treatment of a catecholamine‐secreting glomus jugulare tumor with gamma knife radiosurgery. Head & Neck 2010, 32: 1720-1727. PMID: 19787788, DOI: 10.1002/hed.21242.
- Sperduto PW, Chao ST, Sneed PK, Luo X, Suh J, Roberge D, Bhatt A, Jensen AW, Brown PD, Shih H, Kirkpatrick J, Schwer A, Gaspar LE, Fiveash JB, Chiang V, Knisely J, Sperduto CM, Mehta M. Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients. International Journal Of Radiation Oncology • Biology • Physics 2009, 77: 655-661. PMID: 19942357, DOI: 10.1016/j.ijrobp.2009.08.025.
- Redmond A, Chiang V. Postoperative Management in the Neurosurgical Critical Care Unit. 2009, 294-307. DOI: 10.1017/cbo9780511635434.024.
- Deng J, Chen Z, Knisely J, Decker R, Chiang V, Nath R. Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases. IFMBE Proceedings 2009, 25/1: 13-16. DOI: 10.1007/978-3-642-03474-9_4.
- Redmond AJ, DiLuna ML, Hebert R, Moliterno JA, Desai R, Knisely JP, Chiang VL. Gamma Knife surgery for the treatment of melanoma metastases: the effect of intratumoral hemorrhage on survival. Journal Of Neurosurgery 2008, 109 Suppl: 99-105. PMID: 19123895, DOI: 10.3171/jns/2008/109/12/s16.
- Chamberlain D, Yu J, Roberts K, Higgins S, Mani S, Ozturk A, Chiang V, Knisely J. Detection of Occult Brain Metastasis with High Resolution MRI using Double vs. Single Dose Gadolinium. International Journal Of Radiation Oncology • Biology • Physics 2008, 72: s230-s231. DOI: 10.1016/j.ijrobp.2008.06.702.
- Sperduto P, Sneed P, Bhatt A, Schwer A, Fiveash J, Chiang V, Knisely J, Zhu Y, Gaspar L, Mehta M. A Multi-institutional Validation Study of a New Prognostic Index (Graded Prognostic Assessment, GPA) for Patients with Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2008, 72: s51. DOI: 10.1016/j.ijrobp.2008.06.881.
- Knisely J, Gross C, Castrucci W, Chiang V. Survey of Radiosurgery Practitioner Attitudes on the use of Stereotactic Radiosurgery Alone for Oligometastatic Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2008, 72: s241-s242. DOI: 10.1016/j.ijrobp.2008.06.625.
- DiLuna ML, King JT, Knisely JP, Chiang VL. Prognostic factors for survival after stereotactic radiosurgery vary with the number of cerebral metastases. Cancer 2006, 109: 135-145. PMID: 17133440, DOI: 10.1002/cncr.22367.
- Diluna M, King J, Knisely J, Bond J, De Lotbiniere A, Chiang V. Multivariate analysis identifies factors that affect survival after stereotactic radiosurgery for brain metastases. Journal Of Clinical Oncology 2006, 24: 11500-11500. DOI: 10.1200/jco.2006.24.18_suppl.11500.
- DiLuna ML, Johnson MH, Bi WL, Chiang VL, Duncan CC. Sterile ascites from a ventriculoperitoneal shunt: a case report and review of the literature. Child's Nervous System 2006, 22: 1187-1193. PMID: 16541295, DOI: 10.1007/s00381-006-0054-2.
- Johnson MH, Chiang VL, Ross DA. Interventional Neuroradiology Adjuncts and Alternatives in Patients with Head and Neck Vascular Lesions. Neurosurgery Clinics Of North America 2005, 16: 547-560. PMID: 15990044, DOI: 10.1016/j.nec.2005.04.007.
- Chiang V, Awad I. Mass Effect. 2003, 41-43. DOI: 10.1016/b0-12-226870-9/00658-4.
- Chiang VL, Gailloud P, Murphy KJ, Rigamonti D, Tamargo RJ. Routine intraoperative angiography during aneurysm surgery. Journal Of Neurosurgery 2002, 96: 988-92. PMID: 12066932, DOI: 10.3171/jns.2002.96.6.0988.
- Chiang V, Torbey M, Rigamonti D, Williams M. Ventriculopleural shunt obstruction and positive-pressure ventilation. Case report. Journal Of Neurosurgery 2001, 95: 116-8. PMID: 11453379, DOI: 10.3171/jns.2001.95.1.0116.
- Gary S, Zerillo C, Chiang V, Gaw J, Gray G, Hockfield S. cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma. Gene 2000, 256: 139-147. PMID: 11054543, DOI: 10.1016/s0378-1119(00)00362-0.
- Chiang V, Claus E, Awad I. Toward More Rational Prediction of Outcome in Patients with High-grade Subarachnoid Hemorrhage. Neurosurgery 2000, 46: 28-36. DOI: 10.1093/neurosurgery/46.1.28.
- Chiang V, Claus E, Awad I. Toward more rational prediction of outcome in patients with high-grade subarachnoid hemorrhage. Neurosurgery 2000, 46: 28-35; discussion 35-6. PMID: 10626932, DOI: 10.1097/00006123-200001000-00006.
- Chiang V, Awad I, Berenstein A, Scott M, Spetzler R, Alexander M. Neonatal galenic arteriovenous malformation. Neurosurgery 1999, 44: 847-54. PMID: 10201310, DOI: 10.1097/00006123-199904000-00087.
- Chiang V, Claus E, Chaloupka J, Awad I. Toward More Rational Outcome Prediction in Highgrade Patients with Subarachnoid Hemorrhage. Neurosurgery 1998, 43: 717-718. DOI: 10.1097/00006123-199809000-00371.
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- Yale NeurosurgeryYale Physicians Building800 Howard Avenue, Ste Lower LevelNew Haven, CT 06519