- Yale Physicians Building800 Howard AvenueNew Haven, CT 06519
Sule Tinaz, MD, PhD
Neurology, Movement Disorders
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Neurology
Biography
Sule Tinaz, MD, PhD, is a neurologist who specializes in movement disorders, including Parkinson’s disease, essential tremor, and dystonia. She believes strongly in listening to patients and making them an active agent of the decision-making process for their treatment.
Dr. Tinaz is fascinated by cognitive and behavioral manifestations of Parkinson’s disease and other movement disorders. An assistant professor of neurology at Yale School of Medicine, she conducts research using advanced neuroimaging technologies to better understand these disorders and develop novel therapies.
Titles
- Associate Professor of Neurology
Education & Training
- FellowshipNational Institute of Neurological Disorders and Stroke, Human Motor Control Section (2015)
- ResidencyBoston University Medical Center (2010)
- InternshipAlbert Einstein College of Medicine Montefiore Medical Center (2007)
- PhDBoston University Program in Neuroscience (2007)
- FellowshipDepartment of Neurology, Behavioral Neurology and Movement Disorders Division, Istanbul University (2000)
- MDIstanbul University Cerrahpasa Faculty of Medicine (1998)
Languages Spoken
- English
- Türkçe (Turkish)
Additional Information
Honors & Recognitions
- NINDS R21 Award: Imaging Biomarkers of Exercise-Induced Brain Changes in Parkinson's Disease: (2020)
- NINDS K23 Mentored Career Development Award: Problems with Sustained Motor Performance in Parkinson's Disease and Effect of Neurofeedback: A Functional MRI Investigation: (2019)
- KL2 Mentored Career Development Award: NIH/NCATS (2018)
- YCCI Scholar Award CTSA: Yale University CTSA NCATS (2017)
- NINDS Intramural Competitive Fellowship Award: National Institute of Neurological Disorders and Stroke (2012)
Board Certifications
- AB of Psychiatry & Neurology, Neurology (2010, recertified: 2020)
Publications
- Holmes S, Tinaz S. Neuroimaging Biomarkers in Parkinson’s Disease. Advances In Neurobiology 2024, 40: 617-663. PMID: 39562459, DOI: 10.1007/978-3-031-69491-2_21.
- Honhar P, Sadabad F, Tinaz S, Gallezot J, Dias M, Naganawa M, Yang Y, Henry S, Hillmer A, Gao H, Najafzadeh S, Comley R, Nabulsi N, Huang Y, Finnema S, Carson R, Matuskey D. Clinical correlates of dopamine transporter availability in cross-sectional and longitudinal studies with [18F]FE-PE2I PET: independent validation with new insights. Brain Communications 2024, 6: fcae345. PMID: 39429243, PMCID: PMC11487911, DOI: 10.1093/braincomms/fcae345.
- Holmes S, Honhar P, Tinaz S, Naganawa M, Hilmer A, Gallezot J, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis E, Comley R, Finnema S, Carson R, Matuskey D. Author Correction: Synaptic loss and its association with symptom severity in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 55. PMID: 38472206, PMCID: PMC10933370, DOI: 10.1038/s41531-024-00674-6.
- Holmes S, Honhar P, Tinaz S, Naganawa M, Hilmer A, Gallezot J, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis E, Comley R, Finnema S, Carson R, Matuskey D. Synaptic loss and its association with symptom severity in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 42. PMID: 38402233, PMCID: PMC10894197, DOI: 10.1038/s41531-024-00655-9.
- de Laat B, Hoye J, Stanley G, Hespeler M, Ligi J, Mohan V, Wooten D, Zhang X, Nguyen T, Key J, Colonna G, Huang Y, Nabulsi N, Patel A, Matuskey D, Morris E, Tinaz S. Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 34. PMID: 38336768, PMCID: PMC10858031, DOI: 10.1038/s41531-024-00641-1.
- McGurrin P, Norato G, Thompson‐Westra J, McCrossin G, Lines E, Lungu C, Pandey S, Tinaz S, Voller B, Ramchandani V, Hallett M, Haubenberger D. Objective response to ethanol in essential tremor: results from a standardized ethanol challenge study. Annals Of Clinical And Translational Neurology 2023, 11: 156-168. PMID: 38087917, PMCID: PMC10791018, DOI: 10.1002/acn3.51943.
- Colonna G, Hoye J, de Laat B, Stanley G, Ibrahimy A, Tinaz S, Morris E. Measuring Heart Rate Accurately in Patients With Parkinson Disease During Intense Exercise: Usability Study of Fitbit Charge 4. JMIR Biomedical Engineering 2023, 8: e51515. PMID: 38875680, PMCID: PMC11041416, DOI: 10.2196/51515.
- Tinaz S. Magnetic resonance imaging modalities aid in the differential diagnosis of atypical parkinsonian syndromes. Frontiers In Neurology 2023, 14: 1082060. PMID: 36816565, PMCID: PMC9932598, DOI: 10.3389/fneur.2023.1082060.
- Elfil M, Bayoumi A, Sayed A, Aladawi M, Aboutaleb P, Grieb L, Tolba H, Tinaz S. Stroke in Parkinson’s disease: a review of epidemiological studies and potential pathophysiological mechanisms. Acta Neurologica Belgica 2023, 123: 773-783. PMID: 36710306, DOI: 10.1007/s13760-023-02202-4.
- Cherry J, Kamel S, Elfil M, Aravala S, Bayoumi A, Patel A, Sinha R, Tinaz S. Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease. Brain Imaging And Behavior 2022, 17: 161-171. PMID: 36434490, PMCID: PMC10050121, DOI: 10.1007/s11682-022-00749-z.
- Guo X, Tinaz S, Dvornek N. Characterization of Early Stage Parkinson's Disease From Resting-State fMRI Data Using a Long Short-Term Memory Network. Frontiers In Neuroimaging 2022, 1: 952084. PMID: 37555151, PMCID: PMC10406199, DOI: 10.3389/fnimg.2022.952084.
- Sezgin M, Bilgic B, Tinaz S, Emre M. Parkinson's Disease Dementia and Lewy Body Disease. Seminars In Neurology 2019, 39: 274-282. PMID: 30925619, DOI: 10.1055/s-0039-1678579.
- Tinaz S, Para K, Vives-Rodriguez A, Martinez-Kaigi V, Nalamada K, Sezgin M, Scheinost D, Hampson M, Louis ED, Constable RT. Insula as the Interface Between Body Awareness and Movement: A Neurofeedback-Guided Kinesthetic Motor Imagery Study in Parkinson’s Disease. Frontiers In Human Neuroscience 2018, 12: 496. PMID: 30581383, PMCID: PMC6292989, DOI: 10.3389/fnhum.2018.00496.
- Nalamada K, Tinaz S, Arora J, Vives-Rodriguez A, Constable T, Schilsky M, Robakis D. A comparison of resting-state functional magnetic resonance imaging between Neurological and Liver-only affected Wilson’s Disease patients (P4.014). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p4.014.
- Tinaz S, Nalamada K, Sezgin M, Vives-Rodriguez A, Para K, Scheinost D, Louis E, Hampson M. Functional Magnetic Resonance Imaging-Based Neurofeedback Training in Patients with Parkinson’s Disease (P3.075). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p3.075.
- Tinaz S, Chow C, Kuo PH, Krupinski EA, Blumenfeld H, Louis ED, Zubal G. Semiquantitative Analysis of Dopamine Transporter Scans in Patients With Parkinson Disease. Clinical Nuclear Medicine 2018, 43: e1-e7. PMID: 29112012, PMCID: PMC7257254, DOI: 10.1097/rlu.0000000000001885.
- Tinaz S, Lauro PM, Ghosh P, Lungu C, Horovitz SG. Changes in functional organization and white matter integrity in the connectome in Parkinson's disease. NeuroImage Clinical 2016, 13: 395-404. PMID: 28116232, PMCID: PMC5226806, DOI: 10.1016/j.nicl.2016.12.019.
- Tinaz S, Stern C. The Basal Ganglia and Decision-Making in Neuropsychiatric Disorders. Innovations In Cognitive Neuroscience 2016, 339-361. DOI: 10.1007/978-3-319-42743-0_15.
- Tinaz S, Pillai AS, Hallett M. Sequence Effect in Parkinson’s Disease Is Related to Motor Energetic Cost. Frontiers In Neurology 2016, 7: 83. PMID: 27252678, PMCID: PMC4877367, DOI: 10.3389/fneur.2016.00083.
- Maurer C, LaFaver K, Tinaz S, Hallett M, Horovitz S. Deficits in Sensorimotor Networks in Functional Movement Disorders: A Graph-Theory Based Network Analysis (P1.070). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.p1.070.
- Tinaz S, Malone P, Hallett M, Horovitz SG. Role of the right dorsal anterior insula in the urge to tic in tourette syndrome. Movement Disorders 2015, 30: 1190-1197. PMID: 25855089, PMCID: PMC5088605, DOI: 10.1002/mds.26230.
- Tinaz S, Lauro P, Hallett M, Horovitz SG. Deficits in task-set maintenance and execution networks in Parkinson’s disease. Brain Structure And Function 2015, 221: 1413-1425. PMID: 25567420, PMCID: PMC5565229, DOI: 10.1007/s00429-014-0981-8.
- Tinaz S, Belluscio BA, Malone P, van der Veen J, Hallett M, Horovitz SG. Role of the sensorimotor cortex in tourette syndrome using multimodal imaging. Human Brain Mapping 2014, 35: 5834-5846. PMID: 25044024, PMCID: PMC4776755, DOI: 10.1002/hbm.22588.
- Voller B, Lines E, McCrossin G, Artiles A, Tinaz S, Lungu C, Hallett M, Haubenberger D. Alcohol challenge and the sensitivity to change of the essential tremor rating assessment scale (TETRAS). Journal Of The Neurological Sciences 2013, 333: e77. DOI: 10.1016/j.jns.2013.07.545.
- Jackson S, Parkinson A, Kim S, Schüermann M, Eickhoff S, Proverbio A, Belluscio B, Tinaz S, Hallett M, Rivera-Rei Á, Canales-Johnson A, Huepe D, Ibáñez A, Nachev P, de Haan E, Ganos C, Hummel F, Rothwell J, Edwards M. On the functional anatomy of the urge-for-action. Cognitive Neuroscience 2011, 2: 227-243. PMID: 22299020, PMCID: PMC3259619, DOI: 10.1080/17588928.2011.604717.
- Tinaz S, Courtney MG, Stern CE. Focal cortical and subcortical atrophy in early Parkinson's disease. Movement Disorders 2010, 26: 436-441. PMID: 21462259, PMCID: PMC4502575, DOI: 10.1002/mds.23453.
- Tinaz S, Schendan HE, Schon K, Stern CE. Evidence for the importance of basal ganglia output nuclei in semantic event sequencing: An fMRI study. Brain Research 2005, 1067: 239-249. PMID: 16360121, DOI: 10.1016/j.brainres.2005.10.057.
Departments and Programs
Locations
- Yale Physicians Building800 Howard AvenueNew Haven, CT 06519
Biography
Sule Tinaz, MD, PhD, is a neurologist who specializes in movement disorders, including Parkinson’s disease, essential tremor, and dystonia. She believes strongly in listening to patients and making them an active agent of the decision-making process for their treatment.
Dr. Tinaz is fascinated by cognitive and behavioral manifestations of Parkinson’s disease and other movement disorders. An assistant professor of neurology at Yale School of Medicine, she conducts research using advanced neuroimaging technologies to better understand these disorders and develop novel therapies.
Titles
- Associate Professor of Neurology
Education & Training
- FellowshipNational Institute of Neurological Disorders and Stroke, Human Motor Control Section (2015)
- ResidencyBoston University Medical Center (2010)
- InternshipAlbert Einstein College of Medicine Montefiore Medical Center (2007)
- PhDBoston University Program in Neuroscience (2007)
- FellowshipDepartment of Neurology, Behavioral Neurology and Movement Disorders Division, Istanbul University (2000)
- MDIstanbul University Cerrahpasa Faculty of Medicine (1998)
Languages Spoken
- English
- Türkçe (Turkish)
Additional Information
Honors & Recognitions
- NINDS R21 Award: Imaging Biomarkers of Exercise-Induced Brain Changes in Parkinson's Disease: (2020)
- NINDS K23 Mentored Career Development Award: Problems with Sustained Motor Performance in Parkinson's Disease and Effect of Neurofeedback: A Functional MRI Investigation: (2019)
- KL2 Mentored Career Development Award: NIH/NCATS (2018)
- YCCI Scholar Award CTSA: Yale University CTSA NCATS (2017)
- NINDS Intramural Competitive Fellowship Award: National Institute of Neurological Disorders and Stroke (2012)
Board Certifications
- AB of Psychiatry & Neurology, Neurology (2010, recertified: 2020)
Publications
- Holmes S, Tinaz S. Neuroimaging Biomarkers in Parkinson’s Disease. Advances In Neurobiology 2024, 40: 617-663. PMID: 39562459, DOI: 10.1007/978-3-031-69491-2_21.
- Honhar P, Sadabad F, Tinaz S, Gallezot J, Dias M, Naganawa M, Yang Y, Henry S, Hillmer A, Gao H, Najafzadeh S, Comley R, Nabulsi N, Huang Y, Finnema S, Carson R, Matuskey D. Clinical correlates of dopamine transporter availability in cross-sectional and longitudinal studies with [18F]FE-PE2I PET: independent validation with new insights. Brain Communications 2024, 6: fcae345. PMID: 39429243, PMCID: PMC11487911, DOI: 10.1093/braincomms/fcae345.
- Holmes S, Honhar P, Tinaz S, Naganawa M, Hilmer A, Gallezot J, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis E, Comley R, Finnema S, Carson R, Matuskey D. Author Correction: Synaptic loss and its association with symptom severity in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 55. PMID: 38472206, PMCID: PMC10933370, DOI: 10.1038/s41531-024-00674-6.
- Holmes S, Honhar P, Tinaz S, Naganawa M, Hilmer A, Gallezot J, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis E, Comley R, Finnema S, Carson R, Matuskey D. Synaptic loss and its association with symptom severity in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 42. PMID: 38402233, PMCID: PMC10894197, DOI: 10.1038/s41531-024-00655-9.
- de Laat B, Hoye J, Stanley G, Hespeler M, Ligi J, Mohan V, Wooten D, Zhang X, Nguyen T, Key J, Colonna G, Huang Y, Nabulsi N, Patel A, Matuskey D, Morris E, Tinaz S. Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 34. PMID: 38336768, PMCID: PMC10858031, DOI: 10.1038/s41531-024-00641-1.
- McGurrin P, Norato G, Thompson‐Westra J, McCrossin G, Lines E, Lungu C, Pandey S, Tinaz S, Voller B, Ramchandani V, Hallett M, Haubenberger D. Objective response to ethanol in essential tremor: results from a standardized ethanol challenge study. Annals Of Clinical And Translational Neurology 2023, 11: 156-168. PMID: 38087917, PMCID: PMC10791018, DOI: 10.1002/acn3.51943.
- Colonna G, Hoye J, de Laat B, Stanley G, Ibrahimy A, Tinaz S, Morris E. Measuring Heart Rate Accurately in Patients With Parkinson Disease During Intense Exercise: Usability Study of Fitbit Charge 4. JMIR Biomedical Engineering 2023, 8: e51515. PMID: 38875680, PMCID: PMC11041416, DOI: 10.2196/51515.
- Tinaz S. Magnetic resonance imaging modalities aid in the differential diagnosis of atypical parkinsonian syndromes. Frontiers In Neurology 2023, 14: 1082060. PMID: 36816565, PMCID: PMC9932598, DOI: 10.3389/fneur.2023.1082060.
- Elfil M, Bayoumi A, Sayed A, Aladawi M, Aboutaleb P, Grieb L, Tolba H, Tinaz S. Stroke in Parkinson’s disease: a review of epidemiological studies and potential pathophysiological mechanisms. Acta Neurologica Belgica 2023, 123: 773-783. PMID: 36710306, DOI: 10.1007/s13760-023-02202-4.
- Cherry J, Kamel S, Elfil M, Aravala S, Bayoumi A, Patel A, Sinha R, Tinaz S. Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease. Brain Imaging And Behavior 2022, 17: 161-171. PMID: 36434490, PMCID: PMC10050121, DOI: 10.1007/s11682-022-00749-z.
- Guo X, Tinaz S, Dvornek N. Characterization of Early Stage Parkinson's Disease From Resting-State fMRI Data Using a Long Short-Term Memory Network. Frontiers In Neuroimaging 2022, 1: 952084. PMID: 37555151, PMCID: PMC10406199, DOI: 10.3389/fnimg.2022.952084.
- Sezgin M, Bilgic B, Tinaz S, Emre M. Parkinson's Disease Dementia and Lewy Body Disease. Seminars In Neurology 2019, 39: 274-282. PMID: 30925619, DOI: 10.1055/s-0039-1678579.
- Tinaz S, Para K, Vives-Rodriguez A, Martinez-Kaigi V, Nalamada K, Sezgin M, Scheinost D, Hampson M, Louis ED, Constable RT. Insula as the Interface Between Body Awareness and Movement: A Neurofeedback-Guided Kinesthetic Motor Imagery Study in Parkinson’s Disease. Frontiers In Human Neuroscience 2018, 12: 496. PMID: 30581383, PMCID: PMC6292989, DOI: 10.3389/fnhum.2018.00496.
- Nalamada K, Tinaz S, Arora J, Vives-Rodriguez A, Constable T, Schilsky M, Robakis D. A comparison of resting-state functional magnetic resonance imaging between Neurological and Liver-only affected Wilson’s Disease patients (P4.014). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p4.014.
- Tinaz S, Nalamada K, Sezgin M, Vives-Rodriguez A, Para K, Scheinost D, Louis E, Hampson M. Functional Magnetic Resonance Imaging-Based Neurofeedback Training in Patients with Parkinson’s Disease (P3.075). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p3.075.
- Tinaz S, Chow C, Kuo PH, Krupinski EA, Blumenfeld H, Louis ED, Zubal G. Semiquantitative Analysis of Dopamine Transporter Scans in Patients With Parkinson Disease. Clinical Nuclear Medicine 2018, 43: e1-e7. PMID: 29112012, PMCID: PMC7257254, DOI: 10.1097/rlu.0000000000001885.
- Tinaz S, Lauro PM, Ghosh P, Lungu C, Horovitz SG. Changes in functional organization and white matter integrity in the connectome in Parkinson's disease. NeuroImage Clinical 2016, 13: 395-404. PMID: 28116232, PMCID: PMC5226806, DOI: 10.1016/j.nicl.2016.12.019.
- Tinaz S, Stern C. The Basal Ganglia and Decision-Making in Neuropsychiatric Disorders. Innovations In Cognitive Neuroscience 2016, 339-361. DOI: 10.1007/978-3-319-42743-0_15.
- Tinaz S, Pillai AS, Hallett M. Sequence Effect in Parkinson’s Disease Is Related to Motor Energetic Cost. Frontiers In Neurology 2016, 7: 83. PMID: 27252678, PMCID: PMC4877367, DOI: 10.3389/fneur.2016.00083.
- Maurer C, LaFaver K, Tinaz S, Hallett M, Horovitz S. Deficits in Sensorimotor Networks in Functional Movement Disorders: A Graph-Theory Based Network Analysis (P1.070). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.p1.070.
- Tinaz S, Malone P, Hallett M, Horovitz SG. Role of the right dorsal anterior insula in the urge to tic in tourette syndrome. Movement Disorders 2015, 30: 1190-1197. PMID: 25855089, PMCID: PMC5088605, DOI: 10.1002/mds.26230.
- Tinaz S, Lauro P, Hallett M, Horovitz SG. Deficits in task-set maintenance and execution networks in Parkinson’s disease. Brain Structure And Function 2015, 221: 1413-1425. PMID: 25567420, PMCID: PMC5565229, DOI: 10.1007/s00429-014-0981-8.
- Tinaz S, Belluscio BA, Malone P, van der Veen J, Hallett M, Horovitz SG. Role of the sensorimotor cortex in tourette syndrome using multimodal imaging. Human Brain Mapping 2014, 35: 5834-5846. PMID: 25044024, PMCID: PMC4776755, DOI: 10.1002/hbm.22588.
- Voller B, Lines E, McCrossin G, Artiles A, Tinaz S, Lungu C, Hallett M, Haubenberger D. Alcohol challenge and the sensitivity to change of the essential tremor rating assessment scale (TETRAS). Journal Of The Neurological Sciences 2013, 333: e77. DOI: 10.1016/j.jns.2013.07.545.
- Jackson S, Parkinson A, Kim S, Schüermann M, Eickhoff S, Proverbio A, Belluscio B, Tinaz S, Hallett M, Rivera-Rei Á, Canales-Johnson A, Huepe D, Ibáñez A, Nachev P, de Haan E, Ganos C, Hummel F, Rothwell J, Edwards M. On the functional anatomy of the urge-for-action. Cognitive Neuroscience 2011, 2: 227-243. PMID: 22299020, PMCID: PMC3259619, DOI: 10.1080/17588928.2011.604717.
- Tinaz S, Courtney MG, Stern CE. Focal cortical and subcortical atrophy in early Parkinson's disease. Movement Disorders 2010, 26: 436-441. PMID: 21462259, PMCID: PMC4502575, DOI: 10.1002/mds.23453.
- Tinaz S, Schendan HE, Schon K, Stern CE. Evidence for the importance of basal ganglia output nuclei in semantic event sequencing: An fMRI study. Brain Research 2005, 1067: 239-249. PMID: 16360121, DOI: 10.1016/j.brainres.2005.10.057.
Departments and Programs
Locations
- Yale Physicians Building800 Howard AvenueNew Haven, CT 06519
- Yale Physicians Building800 Howard AvenueNew Haven, CT 06519