Justine Ryu, MD

Lam B, Ito S, Ryu J, O'Sullivan K, Potnis K, Lu R, Bidikian A, Ng D, Singh R, Deter A, Carfagnini C, Bechara S, Kandula M, Do N, Fillmore N, Freed J, Patell R, La J, Goshua G. JAKPOT Prediction Rule for Erythrocytosis: External Validation and Cost‐Effectiveness Analysis. American Journal Of Hematology 2026 PMID: 42227164, DOI: 10.1002/ajh.70390.

Lam B, Ryu J, Jafari O, Kim B, Ma S, Ranjan M, Jiang J, Li A. Epidemiology of Cancer‐Associated Venous Thromboembolism Across the United States. American Journal Of Hematology 2026 PMID: 41796432, DOI: 10.1002/ajh.70271.

Espada A, Haj A, Jurgens S, Eswaran H, Björkman L, Ryu J, Chaudhry S, Koyama S, Wang X, Choi S, Sanna-Cherchi S, Banerji A, Rämö J, Ellinor P, Grover S, Bendapudi P. Population-scale analysis reveals inherited C1-inhibitor deficiency is a polyphenotypic thrombotic disorder. Blood Advances 2026, 10: 931-938. PMID: 41026970, PMCID: PMC12905601, DOI: 10.1182/bloodadvances.2025017220.

Li A, Jafari O, Lam B, Jiang J, Kim B, Ma S, Zhou E, Tiong J, Chiang E, Ryu J, Amos C, La J, Fillmore N. Validation of a Risk Score for Cancer-Associated Thrombosis Using Nationwide EHR Data. JAMA Network Open 2025, 8: e2544428. PMID: 41288979, PMCID: PMC12648341, DOI: 10.1001/jamanetworkopen.2025.44428.

Haj A, Paul D, Jurgens S, Eswaran H, Weng L, Ryu J, Rodriguez Espada A, Chaudhry S, Feingold L, Burke K, Koyama S, Wang X, Francis J, Choi S, Mackman N, Bergmeier W, Burgin A, Rämö J, Ellinor P, Grover S, Bendapudi P. Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis. Nature Communications 2025, 16: 8176. PMID: 40890099, PMCID: PMC12402198, DOI: 10.1038/s41467-025-62789-5.

Jafari O, Ma S, Lam B, Jiang J, Zhou E, Ranjan M, Ryu J, Bandyo R, Maghsoudi A, Peng B, Amos C, Oluyomi A, Fillmore N, La J, Li A. Development and Validation of VTE-BERT Natural Language Processing Model for Venous Thromboembolism. Journal Of Thrombosis And Haemostasis 2025 PMID: 40754035, PMCID: PMC12360494, DOI: 10.1016/j.jtha.2025.07.021.

Chaudhry S, Haj A, Ryu J, Jurgens S, Espada A, Wang X, Choi S, Sanna-Cherchi S, Grover S, Bauer K, Ellinor P, Bendapudi P. Population-Scale Studies of Protein S Abnormalities and Thrombosis. JAMA: The Journal Of The American Medical Association 2025, 333: 1423-1432. PMID: 40029645, PMCID: PMC11877412, DOI: 10.1001/jama.2025.0155.

Kim R, Ryu J, Guffey D, Zhou E, Ranjan M, Ma S, La J, Fillmore N, Li A. Incidence and risk of arterial thromboembolism in cancer patients from a safety-net healthcare system. Journal Of Thrombosis And Haemostasis 2025, 23: 1539-1550. PMID: 39909143, PMCID: PMC12043410, DOI: 10.1016/j.jtha.2025.01.007.

Haj A, Ryu J, Jurgens S, Chaudhry S, Koyama S, Wang X, Choi S, Hou C, Sanna-Cherchi S, Anderson C, Ellinor P, Bendapudi P. Loss of function in protein Z (PROZ) is associated with increased risk of ischemic stroke in the UK Biobank. Journal Of Thrombosis And Haemostasis 2024, 23: 171-180. PMID: 39383998, PMCID: PMC11725435, DOI: 10.1016/j.jtha.2024.09.016.

Ma S, Jiang J, Kim R, Chiang E, Theng Tiong J, Ryu J, Guffey D, Bandyo R, Dowst H, Swinnerton K, Fillmore N, La J, Li A. Circulating tumor DNA predicts venous thromboembolism in patients with cancers. Journal Of Thrombosis And Haemostasis 2024, 23: 139-148. PMID: 39341370, PMCID: PMC12045112, DOI: 10.1016/j.jtha.2024.09.009.

Ryu J, Rämö J, Jurgens S, Niiranen T, Sanna-Cherchi S, Bauer K, Haj A, Choi S, Palotie A, Daly M, Ellinor P, Bendapudi P, Palotie U, Daly M, Riley-Gills B, Jacob H, Viollet C, Petrovski S, Chen C, John S, Okafo G, Plenge R, Maranville J, McCarthy M, Pendergrass R, Ehm M, Auro K, Longerich S, Mälarstig A, Vlahiotis A, Klinger K, Chatelain C, Gossel M, Estrada K, Graham R, Waterworth D, O´Donnell C, Renaud N, Mäkelä T, Kaprio J, Ruddock M, Virolainen P, Hakanen A, Kilpi T, Perola M, Partanen J, Raivio T, Tikkanen J, Serpi R, Kristiansson K, Kosma V, Laukkanen J, Hautalahti M, Tuovila O, Waring J, Riley-Gillis B, Rahimov F, Tachmazidou I, Chen H, Ding Z, Jung M, Tuoken H, Biswas S, Pendergrass R, Ehm M, Pulford D, Raghavan N, Huertas-Vazquez A, Sul J, Mälarstig A, Hu X, Hedman Å, Klinger K, Graham R, Waterworth D, Renaud N, Obeidat M, Chung J, Zierer J, Niemi M, Ripatti S, Schleutker J, Perola M, Arvas M, Carpén O, Hinttala R, Kettunen J, Mannermaa A, Aalto-Setälä K, Kähönen M, Laukkanen M, Mäkelä J, Kälviäinen R, Julkunen V, Soininen H, Remes A, Hiltunen M, Peltola J, Raivio M, Tienari P, Rinne J, Kallionpää R, Partanen J, Ziemann A, Smaoui N, Lehtonen A, Eaton S, Runz H, Lahdenperä S, Biswas S, Bowers N, Teng E, Pendergrass R, Xu F, Pulford D, Auro K, Addis L, Eicher J, Li Q, He K, Khramtsova E, Raghavan N, Färkkilä M, Koskela J, Pikkarainen S, Jussila A, Kaukinen K, Blomster T, Kiviniemi M, Voutilainen M, Daly M, Waring J, Smaoui N, Rahimov F, Lehtonen H, Lu T, Bowers N, Pendergrass R, McCarthy L, Hart A, Guan M, Miller J, Kalpala K, Miller M, Hu X, Eklund K, Palomäki A, Isomäki P, Pirilä L, Kaipiainen-Seppänen O, Huhtakangas J, Mars N, Waring J, Rahimov F, Lertratanakul A, Smaoui N, Lehtonen A, Viollet C, Hochfeld M, Bowers N, Pendergrass R, Gordillo J, Auro K, Waterworth D, Farias F, Kalpala K, Bing N, Hu X, Laitinen T, Pelkonen M, Kauppi P, Kankaanranta H, Harju T, Lahesmaa R, Smaoui N, Viollet C, Eaton S, Chen H, Pendergrass R, Bowers N, Betts J, Auro K, Mishra R, Mouded M, Ngo D, Niiranen T, Vaura F, Salomaa V, Metsärinne K, Aittokallio J, Kähönen M, Hernesniemi J, Gordin D, Sinisalo J, Taskinen M, Tuomi T, Hiltunen T, Laukkanen J, Elliott A, Reeve M, Ruotsalainen S, Paul D, Bowers N, Pendergrass R, Chu A, Auro K, Reilly D, Mendelson M, Parkkinen J, Miller M, Meretoja T, Joensuu H, Carpén O, Mattson J, Salminen E, Auranen A, Karihtala P, Auvinen P, Elenius K, Schleutker J, Pitkänen E, Mars N, Daly M, Popovic R, Waring J, Riley-Gillis B, Lehtonen A, Fabre M, Schutzman J, Bowers N, Pendergrass R, Kulkarni D, Auro K, Porello A, Loboda A, Lehtonen H, McDonough S, Vuoti S, Kaarniranta K, Turunen J, Ollila T, Uusitalo H, Karjalainen J, Pitkänen N, Liu M, Runz H, Loomis S, Strauss E, Bowers N, Chen H, Pendergrass R, Tasanen K, Huilaja L, Hannula-Jouppi K, Salmi T, Peltonen S, Koulu L, Smaoui N, Rahimov F, Lehtonen A, Choy D, Pendergrass R, Waterworth D, Kalpala K, Wu Y, Pussinen P, Salminen A, Salo T, Rice D, Nieminen P, Palotie T, Siponen M, Suominen L, Mäntylä P, Gursoy U, Anttonen V, Sipilä K, Pendergrass R, Laivuori H, Kurra V, Kotaniemi-Talonen L, Heikinheimo O, Kalliala I, Aaltonen L, Jokimaa V, Kettunen J, Vääräsmäki M, Uimari O, Morin-Papunen L, Niinimäki M, Piltonen T, Kivinen K, Widen E, Tukiainen T, Reeve M, Daly M, Välimäki N, Laakkonen E, Tyrmi J, Silven H, Sliz E, Arffman R, Savukoski S, Laisk T, Pujol N, Liu A, Riley-Gillis B, Pendergrass R, Kumar J, Auro K, Hovatta I, Chen C, Isometsä E, Ollila H, Suvisaari J, Mäkitie A, Bizaki-Vallaskangas A, Toppila-Salmi S, Willberg T, Saarentaus E, Aarnisalo A, Salminen E, Rahikkala E, Kettunen J, Aittomäki K, Åberg F, Kurki M, Ripatti S, Daly M, Karjalainen M, Havulinna A, Mehtonen J, Palta P, Hassan S, Della Briotta Parolo P, Zhou W, Maasha M, Hassan S, Lemmelä S, Rivas M, Palotie A, Liu A, Lehisto A, Ganna A, Llorens V, Laivuori H, Tukiainen T, Reeve M, Heyne H, Mars N, Rämö J, Saarentaus E, Ollila H, Rodosthenous R, Strausz S, Palotie T, Palin K, Garcia-Tabuenca J, Siirtola H, Kiiskinen T, Lee J, Tsuo K, Elliott A, Kristiansson K, Arvas M, Hyvärinen K, Ritari J, Carpén O, Kettunen J, Pylkäs K, Sliz E, Karjalainen M, Mantere T, Kangasniemi E, Heikkinen S, Mannermaa A, Laakkonen E, Pitkänen N, Lessard S, Chatelain C, Kallio L, Wahlfors T, Partanen J, Punkka E, Serpi R, Siltanen S, Kosma V, Kuopio T, Jalanko A, Shen H, Kajanne R, Aavikko M, Cooper H, Öller D, Leinonen R, Palin H, Linna M, Kurki M, Karjalainen J, Della Briotta Parolo P, Lehisto A, Mehtonen J, Zhou W, Kanai M, Maasha M, Zheng Z, Laivuori H, Havulinna A, Lemmelä S, Kiiskinen T, Lahtela L, Kaunisto M, Kilpeläinen E, Sipilä T, Dada O, Ghazal A, Kytölä A, Weldatsadik R, Ruotsalainen S, Donner K, Sipilä T, Loukola A, Laiho P, Sistonen T, Kaiharju E, Laukkanen M, Järvensivu E, Lähteenmäki S, Männikkö L, Wong R, Toivola A, Brunfeldt M, Mattsson H, Kristiansson K, Lemmelä S, Koskelainen S, Hiekkalinna T, Paajanen T, Palta P, Luo S, Laitinen T, Reeve M, Padmanabhuni S, Niemi M, Siirtola H, Gracia-Tabuenca J, Helminen M, Luukkaala T, Vähätalo I, Tammerluoto J, Hautalahti M, Mäkelä J, Smith S, Southerington T, Lehto P. Thrombosis risk in single- and double-heterozygous carriers of factor V Leiden and prothrombin G20210A in FinnGen and the UK Biobank. Blood 2024, 143: 2425-2432. PMID: 38498041, PMCID: PMC11830983, DOI: 10.1182/blood.2023023326.

Wang X, Ryu J, Kim J, Ramirez A, Mayo K, Condon H, Vaitinadin N, Ohno-Machado L, Talavera G, Ellinor P, Lubitz S, Choi S. Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program. Journal Of Human Genetics 2023, 68: 565-570. PMID: 37072623, PMCID: PMC10524735, DOI: 10.1038/s10038-023-01147-z.