1
Yale Pediatric Infectious Diseases
Yale New Haven Hospital - West Pavilion
1 Park Street, Fl 2
New Haven, CT 06510
1 of 2
- Yale Pediatric Infectious DiseasesYale New Haven Hospital - West Pavilion1 Park Street, Fl 2New Haven, CT 06510
- Yale Pediatric Infectious DiseaseYale New Haven Hospital20 York StreetNew Haven, CT 06510
I. George Miller Jr, MD
Pediatrics, Pediatric Infectious Diseases, Internal Medicine, Medical Oncology
Telehealth is available
Patient type treated
Child
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Internal Medicine
Biography
I. George Miller, MD, is a pediatric infectious diseases specialist who has a particular interest in the prevention and treatment of viral diseases.
Dr. Miller treats children at Yale New Haven Children’s Hospital and in outpatient clinics and is an active researcher who has studied and published numerous papers on many viruses including poliovirus, measles, vaccinia, herpes simplex, and HIV.
His lab studies two related viruses that can cause cancer in humans: Epstein-Barr, which also causes infectious mononucleosis and is implicated in some autoimmune diseases; and Kaposi’s sarcoma-associated herpes, which is associated with Kaposi’s sarcoma and lymphomas that occur in patients with AIDS.
Dr. Miller is the John F. Enders Professor of Pediatrics (infectious diseases) and professor of epidemiology (microbial diseases) and of molecular biophysics and biochemistry at Yale School of Medicine.
Titles
- John F. Enders Professor of Pediatrics (Infectious Disease) and Professor of Epidemiology (Microbial Diseases) and of Molecular Biophysics and Biochemistry
Education & Training
- Research FellowChildren's Hospital, Boston (1969)
- Research FellowHarvard Medical School (1969)
- FellowCDC (1966)
- Intern & Assistant ResidentUniversity Hospital, Cleveland (1964)
- MDHarvard Medical School (1962)
- ABHarvard College (1958)
Additional Information
Board Certifications
- AB of Internal Medicine, Internal Medicine (1972)
Publications
- Gorres K, Miller G. Cellular Genes Involved in Redox Regulation Are Altered by Inhibitors of Epstein‐Barr Virus Lytic Gene Expression. The FASEB Journal 2019, 33: 458.11-458.11. DOI: 10.1096/fasebj.2019.33.1_supplement.458.11.
- Chang P, Ye J, Miller G. Regulation of Expression, Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation. 2008, 521-553. DOI: 10.1007/978-0-387-68945-6_21.
- Ragoczy T, Miller G. Autostimulation of the Epstein-Barr Virus BRLF1 Promoter Is Mediated through Consensus Sp1 and Sp3 Binding Sites. Journal Of Virology 2001, 75: 5240-5251. PMID: 11333906, PMCID: PMC114930, DOI: 10.1128/jvi.75.11.5240-5251.2001.
- Nikiforow S, Bottomly K, Miller G. CD4+ T-Cell Effectors Inhibit Epstein-Barr Virus-Induced B-Cell Proliferation. Journal Of Virology 2001, 75: 3740-3752. PMID: 11264363, PMCID: PMC114865, DOI: 10.1128/jvi.75.8.3740-3752.2001.
- Almuneef M, Nimjee S, Khoshnood K, Miller G, Rigsby M. PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234. Transplantation 2001, 71: 1120-1124. PMID: 11374413, DOI: 10.1097/00007890-200104270-00019.
- Gradoville L, Gerlach J, Grogan E, Shedd D, Nikiforow S, Metroka C, Miller G. Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50/Rta Protein Activates the Entire Viral Lytic Cycle in the HH-B2 Primary Effusion Lymphoma Cell Line. Journal Of Virology 2000, 74: 6207-6212. PMID: 10846108, PMCID: PMC112123, DOI: 10.1128/jvi.74.13.6207-6212.2000.
- Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.
- Cinquina C, Grogan E, Sun R, Lin S, Beardsley G, Miller G. Dihydrofolate Reductase from Kaposi's Sarcoma-Associated Herpesvirus. Virology 2000, 268: 201-217. PMID: 10683342, DOI: 10.1006/viro.1999.0165.
- Ragoczy T, Miller G. Role of the Epstein-Barr Virus Rta Protein in Activation of Distinct Classes of Viral Lytic Cycle Genes. Journal Of Virology 1999, 73: 9858-9866. PMID: 10559298, PMCID: PMC113035, DOI: 10.1128/jvi.73.12.9858-9866.1999.
- Francis A, Ragoczy T, Gradoville L, Heston L, El-Guindy A, Endo Y, Miller G. Amino Acid Substitutions Reveal Distinct Functions of Serine 186 of the ZEBRA Protein in Activation of Early Lytic Cycle Genes and Synergy with the Epstein-Barr Virus R Transactivator. Journal Of Virology 1999, 73: 4543-4551. PMID: 10233912, PMCID: PMC112494, DOI: 10.1128/jvi.73.6.4543-4551.1999.
- Staskus K, Sun R, Miller G, Racz P, Jaslowski A, Metroka C, Brett-Smith H, Haase A. Cellular Tropism and Viral Interleukin-6 Expression Distinguish Human Herpesvirus 8 Involvement in Kaposi’s Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman’s Disease. Journal Of Virology 1999, 73: 4181-4187. PMID: 10196314, PMCID: PMC104197, DOI: 10.1128/jvi.73.5.4181-4187.1999.
- Staskus K, Sun R, Miller G, Haase A. CELLULAR TROPISM AND LEVELS OF VIRAL GENE EXPRESSION DISTINGUISH HHV-8 INVOLVEMENT IN KS, PEL AND MCD. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: a13. DOI: 10.1097/00126334-199905010-00034.
- Staskus K, Sun R, Miller G, Haase A. Identification and Characterization of the Two Promoter Elements of the Open Reading Frame 50 (ORF50) of Kaposi's Sarcoma-Associated Herpesvirus (KSHV). JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: a13. DOI: 10.1097/00126334-199905010-00035.
- Lin S, Robinson D, Miller G, Kung H. Kaposi’s Sarcoma-Associated Herpesvirus Encodes a bZIP Protein with Homology to BZLF1 of Epstein-Barr Virus. Journal Of Virology 1999, 73: 1909-1917. PMID: 9971770, PMCID: PMC104432, DOI: 10.1128/jvi.73.3.1909-1917.1999.
- Sun R, Lin S, Staskus K, Gradoville L, Grogan E, Haase A, Miller G. Kinetics of Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression. Journal Of Virology 1999, 73: 2232-2242. PMID: 9971806, PMCID: PMC104468, DOI: 10.1128/jvi.73.3.2232-2242.1999.
- Ragoczy T, Heston L, Miller G. The Epstein-Barr Virus Rta Protein Activates Lytic Cycle Genes and Can Disrupt Latency in B Lymphocytes. Journal Of Virology 1998, 72: 7978-7984. PMID: 9733836, PMCID: PMC110133, DOI: 10.1128/jvi.72.10.7978-7984.1998.
- Serio T, Cahill N, Prout M, Miller G. A Functionally Distinct TATA Box Required for Late Progression through the Epstein-Barr Virus Life Cycle. Journal Of Virology 1998, 72: 8338-8343. PMID: 9733880, PMCID: PMC110205, DOI: 10.1128/jvi.72.10.8338-8343.1998.
- Sun R, Lin S, Gradoville L, Yuan Y, Zhu F, Miller G. A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 10866-10871. PMID: 9724796, PMCID: PMC27987, DOI: 10.1073/pnas.95.18.10866.
- Cottoni F, Angeloni A, Heston L, Uccini S, Sirianni M, Masala M, Cerimele D, Rigsby M, Faggioni A, Miller G. High prevalence of antibodies to human herpesvirus-8 in relatives of patients with classic Kaposi's sarcoma from Sardinia. Journal Of The European Academy Of Dermatology And Venereology 1998, 11: s174. DOI: 10.1016/s0926-9959(98)95202-3.
- Angeloni A, Heston L, Uccini S, Sirianni M, Cottoni F, Masala M, Cerimele D, Lin S, Sun R, Rigsby M, Faggioni A, Miller G. High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia. The Journal Of Infectious Diseases 1998, 177: 1715-1718. PMID: 9607855, DOI: 10.1086/517429.
- Wajeh Q, Othman A, Khalid A, Lin3 4, Ren S, Lee H, Ross5 6, Rigsby7 8, Miller3 5. SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1. Transplantation 1998, 65: 583-585. PMID: 9500639, DOI: 10.1097/00007890-199802270-00024.
- Spain T, Sun R, Miller G. The Locus of Epstein–Barr Virus Terminal Repeat Processing Is Bound with Enhanced Affinity by Sp1 and Sp3. Virology 1997, 237: 137-147. PMID: 9344916, DOI: 10.1006/viro.1997.8770.
- Miller G. #412 Epstein-Barr virus associated diseases, pathogenesis and novel approaches to therapy. Journal Of Pediatric Hematology/Oncology 1997, 19: 359. DOI: 10.1097/00043426-199707000-00030.
- Spain T, Sun R, Gradzka M, Lin S, Craft J, Miller G. The transcriptional activator Sp1, a novel autoantigen. Arthritis & Rheumatism 1997, 40: 1085-1095. PMID: 9182919, DOI: 10.1002/art.1780400613.
- Miller G, Rigsby M, Heston L, Grogan E, Sun R, Metroka C, Levy J, Gao S, Chang Y, Moore P. Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection. New England Journal Of Medicine 1996, 334: 1292-1297. PMID: 8609946, DOI: 10.1056/nejm199605163342003.
- Sun R, Grogan E, Shedd D, Bykovsky A, Kushnaryov V, Grossberg S, Miller G. Transmissible Retrovirus in Epstein-Burr Virus-Producer B95-8 Cells. Virology 1995, 209: 374-383. PMID: 7778272, DOI: 10.1006/viro.1995.1269.
- Ikeda M, Andiman W, Mezger J, Shapiro E, Miller G. Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1. The Journal Of Pediatrics 1993, 122: 524-531. PMID: 8463895, DOI: 10.1016/s0022-3476(05)83530-9.
- Pedneault L, Katz B, Miller G. Detection of Epstein‐Barr virus in the brain by the polymerase chain reaction. Annals Of Neurology 1992, 32: 184-192. PMID: 1324632, DOI: 10.1002/ana.410320210.
- Brenner TJ, Dahl KE, Miller G, Andiman W, Andiman WA, Olson B, Miller G, Andiman W, Miller G. Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children. The Lancet 1991, 337: 1001-1005. PMID: 1673167, DOI: 10.1016/0140-6736(91)92660-t.
- Pedneault L, Katz B, Miller G. The Association of Epstein-Barr Virus with Lymphoproliferative Disorders: A Re-evaluation Using the Polymerase Chain Reaction. Experimental Biology And Medicine 1991, 273-276. DOI: 10.1007/978-1-4612-0405-3_39.
- Rhim J, Arnstein P, Fahraeus R, Rymo L, Klein G, Gradoville L, Miller G, Wang F, Kieff E. Interaction of EBV Genes with Human Epithelial Cells. Experimental Biology And Medicine 1991, 339-345. DOI: 10.1007/978-1-4612-0405-3_48.
- Miller G, Taylor N, Kolman J, Baumann R, Katz D, Himmelfarb H, Carey M, Ptashne M. How Zebra, A Weak Transactivator, Exerts Strong Biologic Effects. Experimental Biology And Medicine 1991, 27-42. DOI: 10.1007/978-1-4612-0405-3_4.
- Taylor N, Kolman J, Miller G. Heterodimers of the Zebra and Fos Basic Domains Bind DNA with the Specificity of Zebra. Experimental Biology And Medicine 1991, 99-103. DOI: 10.1007/978-1-4612-0405-3_15.
- Gradoville L, Grogan E, Taylor N, Miller G. Differences in the extent of activation of Epstein-Barr virus replicative gene expression among four nonproducer cell lines stably transformed by OriP/BZLF1 plasmids. Virology 1990, 178: 345-354. PMID: 2171186, DOI: 10.1016/0042-6822(90)90331-k.
- Orlowski R, Polvino-Bodnar M, Hearing J, Miller G. Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies. Virology 1990, 176: 638-642. PMID: 2161154, DOI: 10.1016/0042-6822(90)90036-q.
- Orlowski R, Miller G. Topological Effects of EBNA 1 on oriP. Advances In Experimental Medicine And Biology 1990, 278: 115-124. PMID: 1963028, DOI: 10.1007/978-1-4684-5853-4_12.
- Miller G, Talyor N, Countryman J, Rooney C, Katz D, Kolman J, Jenson H, Grogan E, Gradoville L. Role of The Zebra Protein in the Switch Between Epstein-Barr Virus Latency and Replication. Experimental Biology And Medicine 1989, 17-35. DOI: 10.1007/978-1-4612-4508-7_2.
- Jenson H, Miller G. Polymorphisms of the region of the Epstein-Barr virus genome which disrupts latency. Virology 1988, 165: 549-564. PMID: 2841800, DOI: 10.1016/0042-6822(88)90599-5.
- Ho M, Jaffe R, Miller G, Breinig M, Dummer J, Makowka L, Atchison R, Karrer F, Nalesnik M, Starzl T. THE FREQUENCY OF EPSTEIN-BARR VIRUS INFECTION AND ASSOCIATED LYMPHOPROLIFERATIVE SYNDROME AFTER TRANSPLANTATION AND ITS MANIFESTATIONS IN CHILDREN. Transplantation 1988, 45: 719-726. PMID: 2833828, PMCID: PMC2993427, DOI: 10.1097/00007890-198804000-00011.
- Rowe D, Farrell P, Miller G. Novel nuclear antigens recognized by human sera in lymphocytes latently infected by Epstein-Barr virus. Virology 1987, 156: 153-162. PMID: 3027963, DOI: 10.1016/0042-6822(87)90446-6.
- Miller G, Countryman J, Jenson H, Grogan E, Gradoville L. Disruption of Latency by a Fragment of Rearranged EBV DNA: Evidence for Host Cell Regulation. Experimental Biology And Medicine 1987, 197-206. DOI: 10.1007/978-1-4612-4590-2_44.
- Rosenberg N, Hochberg F, Miller G, Kleinschmidt‐DeMasters B. Primary central nervous system lymphoma related to Epstein‐Barr virus in a patient with acquired immune deficiency syndrome. Annals Of Neurology 1986, 20: 98-102. PMID: 3017188, DOI: 10.1002/ana.410200118.
- MILLER G. Animal model for Epstein-Barr lymphoma. Nature 1986, 319: 626-626. PMID: 3005864, DOI: 10.1038/319626c0.
- Andiman W, Katz B, Miller G. Progressive Epstein-Barr Virus Infection. 1986, 276-286. DOI: 10.1007/978-1-4612-4958-0_33.
- Andiman W, Martin K, Rubinstein A, Pahwa S, Eastman R, Katz B, Pitt J, Miller G. OPPORTUNISTIC LYMPHOPROLIFERATIONS ASSOCIATED WITH EPSTEIN-BARR VIRAL DNA IN INFANTS AND CHILDREN WITH AIDS. The Lancet 1985, 326: 1390-1393. DOI: 10.1016/s0140-6736(85)92557-7.
- Rowe D, Heston L, Metlay J, Miller G. Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 7429-7433. PMID: 2997790, PMCID: PMC391358, DOI: 10.1073/pnas.82.21.7429.
- Miller G, Sugden B. An identification of a transforming region of Epstein-Barr viral DNA cannot be confirmed. Virology 1985, 143: 478-484. PMID: 2998023, DOI: 10.1016/0042-6822(85)90387-3.
- Katz B, Andiman W, Miller G. 1119 INFECTION WITH MULTIPLE EB VIRUS (EBV) GENOTYPES IN AN INFANT WITH AIDS AND HIS MOTHER. Pediatric Research 1985, 19: 297-297. DOI: 10.1203/00006450-198504000-01149.
- Miller G, Grogan E, Fischer D, Niederman J, Schooley R, Henle W, Lenoir G, Liu C. Antibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer. New England Journal Of Medicine 1985, 312: 750-755. PMID: 2983211, DOI: 10.1056/nejm198503213121204.
- Schubach W, Miller G, Thomas E. Epstein-Barr Virus Genomes Are Restricted to Secondary Neoplastic Cells Following Bone Marrow Transplantation. Blood 1985, 65: 535-538. DOI: 10.1182/blood.v65.3.535.535.
- Weigel R, Fischer D, Heston L, Miller G. Constitutive expression of Epstein-Barr virus-encoded RNAs and nuclear antigen during latency and after induction of Epstein-Barr virus replication. Journal Of Virology 1985, 53: 254-259. PMID: 2981344, PMCID: PMC255024, DOI: 10.1128/jvi.53.1.254-259.1985.
- Schmidt W, Sue McIntosh L, Miller G, Andiman W, Dwyer J, Lomax K. REVERSAL OF SIGNS AND SYMPTOMS OF ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) WITH PREDNISONE. Pediatric Research 1984, 18: 264-264. DOI: 10.1203/00006450-198404001-01029.
- Miller G, Rabson M, Heston L. Epstein-Barr virus with heterogeneous DNA disrupts latency. Journal Of Virology 1984, 50: 174-182. PMID: 6321789, PMCID: PMC255597, DOI: 10.1128/jvi.50.1.174-182.1984.
- Miller G. Burkitt Lymphoma. 1984, 599-619. DOI: 10.1007/978-1-4684-4727-9_24.
- Miller G. Regions of the EBV genome involved in latency and lymphocyte immortalization. Medical Virology 1984, 30: 107-28. PMID: 6087408.
- Hochberg F, Miller G, Schooley R, Hirsch M, Feorino P, Henle W. Central-Nervous-System Lymphoma Related to Epstein–Barr Virus. New England Journal Of Medicine 1983, 309: 745-748. PMID: 6310394, DOI: 10.1056/nejm198309293091301.
- Rabson M, Heston L, Miller G. Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1983, 80: 2762-2766. PMID: 6302703, PMCID: PMC393908, DOI: 10.1073/pnas.80.9.2762.
- Coope D, von Graevenitz A, Corrales J, Miller G. Tissue Culture Contamination with Nontuberculous Mycobacteria. Microbiology And Immunology 1983, 27: 113-115. PMID: 6865803, DOI: 10.1111/j.1348-0421.1983.tb03563.x.
- Miller G, Heston L, Hoffman G. Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody. Infection And Immunity 1982, 37: 1028-1031. PMID: 6182100, PMCID: PMC347642, DOI: 10.1128/iai.37.3.1028-1031.1982.
- Schubach W, Hackman R, Neiman P, Miller G, Thomas E. A Monoclonal Immunoblastic Sarcoma in Donor Cells Bearing Epstein-Barr Virus Genomes Following Allogeneic Marrow Grafting for Acute Lymphoblastic Leukemia. Blood 1982, 60: 180-187. DOI: 10.1182/blood.v60.1.180.180.
- Miller G. Burkitt Lymphoma. 1982, 599-619. DOI: 10.1007/978-1-4613-3237-4_24.
- Robinson J, Miller G. Biology of Lymphoid Cells Transformed by Epstein—Barr Virus. The Viruses 1982, 151-207. DOI: 10.1007/978-1-4684-4163-5_4.
- Heston L, Rabson M, Brown N, Miller G. New Epstein–Barr virus variants from cellular subclones of P3J-HR-1 Burkitt lymphoma. Nature 1982, 295: 160-163. PMID: 6276755, DOI: 10.1038/295160a0.
- Anvret M, Miller G. Copy number and location of Epstein-Barr viral genomes in neonatal human lymphocytes transformed after separation by size and treatment with mitogens. Virology 1981, 111: 47-55. PMID: 6263010, DOI: 10.1016/0042-6822(81)90652-8.
- Fischer D, Miller G, Gradoville L, Heston L, Weststrate M, Maris W, Wright J, Brandsma J, Summers W. Genome of a mononucleosis epstein-barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates. Cell 1981, 24: 543-553. PMID: 6263500, DOI: 10.1016/0092-8674(81)90345-7.
- Miller G, Grogan E, Heston L, Robinson J, Smith D. Epstein-Barr Viral DNA: Infectivity for Human Placental Cells. Science 1981, 212: 452-455. PMID: 6259735, DOI: 10.1126/science.6259735.
- Robinson J, Brown N, Andiman W, Halliday K, Francke U, Robert M, Andersson-Anvret M, Horstmann D, Miller G. Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus. New England Journal Of Medicine 1980, 302: 1293-1297. PMID: 6245364, DOI: 10.1056/nejm198006053022306.
- Morgan DG, Miller G, Niederman J, Smith HW, Dowaliby JM. SITE OF EPSTEIN-BARR VIRUS REPLICATION IN THE OROPHARYNX. The Lancet 1979, 314: 1154-1157. PMID: 91888, DOI: 10.1016/s0140-6736(79)92384-5.
- Coope D, Heston L, Brandsma J, Miller G. Cross-neutralization of infectious mononucleosis and Burkitt lymphoma strains of Epstein-Barr virus with hyperimmune rabbit antisera. The Journal Of Immunology 1979, 123: 232-8. PMID: 221591, DOI: 10.4049/jimmunol.123.1.232.
- Miller G. Experimental Carcinogenicity by the Virus In Vivo. 1979, 351-372. DOI: 10.1007/978-3-642-67236-1_16.
- Henderson E, Heston L, Grogan E, Miller G. Radiobiological Inactivation of Epstein-Barr Virus. Journal Of Virology 1978, 25: 51-59. PMID: 202757, PMCID: PMC353900, DOI: 10.1128/jvi.25.1.51-59.1978.
- Henderson E, Miller G, Robinson J, Heston L. Efficiency of transformation of lymphocytes by Epstein-Barr virus. Virology 1977, 76: 152-163. PMID: 189490, DOI: 10.1016/0042-6822(77)90292-6.
- Niederman J, Miller G, Pearson H, Pagano J, Dowaliby J. Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx. New England Journal Of Medicine 1976, 294: 1355-1359. PMID: 177872, DOI: 10.1056/nejm197606172942501.
- Miller G. Epidemiology of Burkitt Lymphoma. 1976, 481-499. DOI: 10.1007/978-1-4613-3988-5_22.
- Miller G, Robinson J, Heston L, Lipman M. Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection and interference. IARC Scientific Publications 1975, 395-408. PMID: 190145.
- Miller G, Robinson J, Heston L, Lipman M. Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference. Proceedings Of The National Academy Of Sciences Of The United States Of America 1974, 71: 4006-4010. PMID: 4372601, PMCID: PMC434316, DOI: 10.1073/pnas.71.10.4006.
- Siegel N, Strauch B, Andrews L, Miller G, Cook C. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. Pediatric Research 1974, 8: 428-428. DOI: 10.1203/00006450-197404000-00531.
- Strauch B, Siegel N, Andrews L, Miller G. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. The Lancet 1974, 303: 234-237. PMID: 4130246, DOI: 10.1016/s0140-6736(74)92546-x.
- Miller G, Robinson J, Heston L. Immortalizing and nonimmortalizing laboratory strains of Epstein-Barr Virus. Cold Spring Harbor Symposia On Quantitative Biology 1974, 39 Pt 2: 773-81. PMID: 169031, DOI: 10.1101/sqb.1974.039.01.089.
- Miller G, Heston L. Expression of Epstein-Barr viral capsid, complement fixing, and nuclear antigens in stationary and exponential phase cultures. The Yale Journal Of Biology And Medicine 1974, 47: 123-35. PMID: 4372815, PMCID: PMC2596417.
- Shope T, Dechairo D, Miller G. Malignant Lymphoma in Cottontop Marmosets after Inoculation with Epstein-Barr Virus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 2487-2491. PMID: 4354852, PMCID: PMC427039, DOI: 10.1073/pnas.70.9.2487.
- Miller G, Niederman J, Andrews L. Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis. New England Journal Of Medicine 1973, 288: 229-232. PMID: 4345064, DOI: 10.1056/nejm197302012880503.
- Miller G, Lipman M. Release of Infectious Epstein-Barr Virus by Transformed Marmoset Leukocytes. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 190-194. PMID: 4346033, PMCID: PMC433213, DOI: 10.1073/pnas.70.1.190.
- Miller G, Shope T, Heston L, O'Brien R, Schwartz A, Pearson H. Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood. The Journal Of Pediatrics 1972, 80: 932-937. PMID: 4337277, DOI: 10.1016/s0022-3476(72)80004-0.
- Miller G, Shope T, Lisco H, Stitt D, Lipman M. Epstein-Barr Virus: Transformation, Cytopathic Changes, and Viral Antigens in Squirrel Monkey and Marmoset Leukocytes. Proceedings Of The National Academy Of Sciences Of The United States Of America 1972, 69: 383-387. PMID: 4333982, PMCID: PMC426463, DOI: 10.1073/pnas.69.2.383.
- Miller M, Stitt D, Miller G. Epstein-Barr viral antigen in single cell clones of two human leukocytic lines. Journal Of Virology 1970, 6: 699-701. PMID: 4320703, PMCID: PMC376178, DOI: 10.1128/jvi.6.5.699-701.1970.
- Grogan E, Enders J, Miller G. Trypsinized Placental Cell Cultures for the Propagation of Viruses and as “Feeder Layers”. Journal Of Virology 1970, 5: 406-409. PMID: 4314557, PMCID: PMC376018, DOI: 10.1128/jvi.5.3.406-409.1970.
- Miller G, Enders J, Lisco H, Kohn H. Establishment of Lines from Normal Human Blood Leukocytes by Co-cultivation with a Leukocyte Line Derived from a Leukemic Child 1. Experimental Biology And Medicine 1969, 132: 247-252. PMID: 4899209, DOI: 10.3181/00379727-132-34189.
Locations
1
Yale Pediatric Infectious Diseases
Yale New Haven Hospital - West Pavilion
1 Park Street, Fl 2
New Haven, CT 06510
1 of 2
- Yale Pediatric Infectious DiseasesYale New Haven Hospital - West Pavilion1 Park Street, Fl 2New Haven, CT 06510
- Yale Pediatric Infectious DiseaseYale New Haven Hospital20 York StreetNew Haven, CT 06510
Biography
I. George Miller, MD, is a pediatric infectious diseases specialist who has a particular interest in the prevention and treatment of viral diseases.
Dr. Miller treats children at Yale New Haven Children’s Hospital and in outpatient clinics and is an active researcher who has studied and published numerous papers on many viruses including poliovirus, measles, vaccinia, herpes simplex, and HIV.
His lab studies two related viruses that can cause cancer in humans: Epstein-Barr, which also causes infectious mononucleosis and is implicated in some autoimmune diseases; and Kaposi’s sarcoma-associated herpes, which is associated with Kaposi’s sarcoma and lymphomas that occur in patients with AIDS.
Dr. Miller is the John F. Enders Professor of Pediatrics (infectious diseases) and professor of epidemiology (microbial diseases) and of molecular biophysics and biochemistry at Yale School of Medicine.
Titles
- John F. Enders Professor of Pediatrics (Infectious Disease) and Professor of Epidemiology (Microbial Diseases) and of Molecular Biophysics and Biochemistry
Education & Training
- Research FellowChildren's Hospital, Boston (1969)
- Research FellowHarvard Medical School (1969)
- FellowCDC (1966)
- Intern & Assistant ResidentUniversity Hospital, Cleveland (1964)
- MDHarvard Medical School (1962)
- ABHarvard College (1958)
Additional Information
Board Certifications
- AB of Internal Medicine, Internal Medicine (1972)
Publications
- Gorres K, Miller G. Cellular Genes Involved in Redox Regulation Are Altered by Inhibitors of Epstein‐Barr Virus Lytic Gene Expression. The FASEB Journal 2019, 33: 458.11-458.11. DOI: 10.1096/fasebj.2019.33.1_supplement.458.11.
- Chang P, Ye J, Miller G. Regulation of Expression, Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation. 2008, 521-553. DOI: 10.1007/978-0-387-68945-6_21.
- Ragoczy T, Miller G. Autostimulation of the Epstein-Barr Virus BRLF1 Promoter Is Mediated through Consensus Sp1 and Sp3 Binding Sites. Journal Of Virology 2001, 75: 5240-5251. PMID: 11333906, PMCID: PMC114930, DOI: 10.1128/jvi.75.11.5240-5251.2001.
- Nikiforow S, Bottomly K, Miller G. CD4+ T-Cell Effectors Inhibit Epstein-Barr Virus-Induced B-Cell Proliferation. Journal Of Virology 2001, 75: 3740-3752. PMID: 11264363, PMCID: PMC114865, DOI: 10.1128/jvi.75.8.3740-3752.2001.
- Almuneef M, Nimjee S, Khoshnood K, Miller G, Rigsby M. PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234. Transplantation 2001, 71: 1120-1124. PMID: 11374413, DOI: 10.1097/00007890-200104270-00019.
- Gradoville L, Gerlach J, Grogan E, Shedd D, Nikiforow S, Metroka C, Miller G. Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50/Rta Protein Activates the Entire Viral Lytic Cycle in the HH-B2 Primary Effusion Lymphoma Cell Line. Journal Of Virology 2000, 74: 6207-6212. PMID: 10846108, PMCID: PMC112123, DOI: 10.1128/jvi.74.13.6207-6212.2000.
- Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.
- Cinquina C, Grogan E, Sun R, Lin S, Beardsley G, Miller G. Dihydrofolate Reductase from Kaposi's Sarcoma-Associated Herpesvirus. Virology 2000, 268: 201-217. PMID: 10683342, DOI: 10.1006/viro.1999.0165.
- Ragoczy T, Miller G. Role of the Epstein-Barr Virus Rta Protein in Activation of Distinct Classes of Viral Lytic Cycle Genes. Journal Of Virology 1999, 73: 9858-9866. PMID: 10559298, PMCID: PMC113035, DOI: 10.1128/jvi.73.12.9858-9866.1999.
- Francis A, Ragoczy T, Gradoville L, Heston L, El-Guindy A, Endo Y, Miller G. Amino Acid Substitutions Reveal Distinct Functions of Serine 186 of the ZEBRA Protein in Activation of Early Lytic Cycle Genes and Synergy with the Epstein-Barr Virus R Transactivator. Journal Of Virology 1999, 73: 4543-4551. PMID: 10233912, PMCID: PMC112494, DOI: 10.1128/jvi.73.6.4543-4551.1999.
- Staskus K, Sun R, Miller G, Racz P, Jaslowski A, Metroka C, Brett-Smith H, Haase A. Cellular Tropism and Viral Interleukin-6 Expression Distinguish Human Herpesvirus 8 Involvement in Kaposi’s Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman’s Disease. Journal Of Virology 1999, 73: 4181-4187. PMID: 10196314, PMCID: PMC104197, DOI: 10.1128/jvi.73.5.4181-4187.1999.
- Staskus K, Sun R, Miller G, Haase A. CELLULAR TROPISM AND LEVELS OF VIRAL GENE EXPRESSION DISTINGUISH HHV-8 INVOLVEMENT IN KS, PEL AND MCD. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: a13. DOI: 10.1097/00126334-199905010-00034.
- Staskus K, Sun R, Miller G, Haase A. Identification and Characterization of the Two Promoter Elements of the Open Reading Frame 50 (ORF50) of Kaposi's Sarcoma-Associated Herpesvirus (KSHV). JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: a13. DOI: 10.1097/00126334-199905010-00035.
- Lin S, Robinson D, Miller G, Kung H. Kaposi’s Sarcoma-Associated Herpesvirus Encodes a bZIP Protein with Homology to BZLF1 of Epstein-Barr Virus. Journal Of Virology 1999, 73: 1909-1917. PMID: 9971770, PMCID: PMC104432, DOI: 10.1128/jvi.73.3.1909-1917.1999.
- Sun R, Lin S, Staskus K, Gradoville L, Grogan E, Haase A, Miller G. Kinetics of Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression. Journal Of Virology 1999, 73: 2232-2242. PMID: 9971806, PMCID: PMC104468, DOI: 10.1128/jvi.73.3.2232-2242.1999.
- Ragoczy T, Heston L, Miller G. The Epstein-Barr Virus Rta Protein Activates Lytic Cycle Genes and Can Disrupt Latency in B Lymphocytes. Journal Of Virology 1998, 72: 7978-7984. PMID: 9733836, PMCID: PMC110133, DOI: 10.1128/jvi.72.10.7978-7984.1998.
- Serio T, Cahill N, Prout M, Miller G. A Functionally Distinct TATA Box Required for Late Progression through the Epstein-Barr Virus Life Cycle. Journal Of Virology 1998, 72: 8338-8343. PMID: 9733880, PMCID: PMC110205, DOI: 10.1128/jvi.72.10.8338-8343.1998.
- Sun R, Lin S, Gradoville L, Yuan Y, Zhu F, Miller G. A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 10866-10871. PMID: 9724796, PMCID: PMC27987, DOI: 10.1073/pnas.95.18.10866.
- Cottoni F, Angeloni A, Heston L, Uccini S, Sirianni M, Masala M, Cerimele D, Rigsby M, Faggioni A, Miller G. High prevalence of antibodies to human herpesvirus-8 in relatives of patients with classic Kaposi's sarcoma from Sardinia. Journal Of The European Academy Of Dermatology And Venereology 1998, 11: s174. DOI: 10.1016/s0926-9959(98)95202-3.
- Angeloni A, Heston L, Uccini S, Sirianni M, Cottoni F, Masala M, Cerimele D, Lin S, Sun R, Rigsby M, Faggioni A, Miller G. High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia. The Journal Of Infectious Diseases 1998, 177: 1715-1718. PMID: 9607855, DOI: 10.1086/517429.
- Wajeh Q, Othman A, Khalid A, Lin3 4, Ren S, Lee H, Ross5 6, Rigsby7 8, Miller3 5. SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1. Transplantation 1998, 65: 583-585. PMID: 9500639, DOI: 10.1097/00007890-199802270-00024.
- Spain T, Sun R, Miller G. The Locus of Epstein–Barr Virus Terminal Repeat Processing Is Bound with Enhanced Affinity by Sp1 and Sp3. Virology 1997, 237: 137-147. PMID: 9344916, DOI: 10.1006/viro.1997.8770.
- Miller G. #412 Epstein-Barr virus associated diseases, pathogenesis and novel approaches to therapy. Journal Of Pediatric Hematology/Oncology 1997, 19: 359. DOI: 10.1097/00043426-199707000-00030.
- Spain T, Sun R, Gradzka M, Lin S, Craft J, Miller G. The transcriptional activator Sp1, a novel autoantigen. Arthritis & Rheumatism 1997, 40: 1085-1095. PMID: 9182919, DOI: 10.1002/art.1780400613.
- Miller G, Rigsby M, Heston L, Grogan E, Sun R, Metroka C, Levy J, Gao S, Chang Y, Moore P. Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection. New England Journal Of Medicine 1996, 334: 1292-1297. PMID: 8609946, DOI: 10.1056/nejm199605163342003.
- Sun R, Grogan E, Shedd D, Bykovsky A, Kushnaryov V, Grossberg S, Miller G. Transmissible Retrovirus in Epstein-Burr Virus-Producer B95-8 Cells. Virology 1995, 209: 374-383. PMID: 7778272, DOI: 10.1006/viro.1995.1269.
- Ikeda M, Andiman W, Mezger J, Shapiro E, Miller G. Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1. The Journal Of Pediatrics 1993, 122: 524-531. PMID: 8463895, DOI: 10.1016/s0022-3476(05)83530-9.
- Pedneault L, Katz B, Miller G. Detection of Epstein‐Barr virus in the brain by the polymerase chain reaction. Annals Of Neurology 1992, 32: 184-192. PMID: 1324632, DOI: 10.1002/ana.410320210.
- Brenner TJ, Dahl KE, Miller G, Andiman W, Andiman WA, Olson B, Miller G, Andiman W, Miller G. Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children. The Lancet 1991, 337: 1001-1005. PMID: 1673167, DOI: 10.1016/0140-6736(91)92660-t.
- Pedneault L, Katz B, Miller G. The Association of Epstein-Barr Virus with Lymphoproliferative Disorders: A Re-evaluation Using the Polymerase Chain Reaction. Experimental Biology And Medicine 1991, 273-276. DOI: 10.1007/978-1-4612-0405-3_39.
- Rhim J, Arnstein P, Fahraeus R, Rymo L, Klein G, Gradoville L, Miller G, Wang F, Kieff E. Interaction of EBV Genes with Human Epithelial Cells. Experimental Biology And Medicine 1991, 339-345. DOI: 10.1007/978-1-4612-0405-3_48.
- Miller G, Taylor N, Kolman J, Baumann R, Katz D, Himmelfarb H, Carey M, Ptashne M. How Zebra, A Weak Transactivator, Exerts Strong Biologic Effects. Experimental Biology And Medicine 1991, 27-42. DOI: 10.1007/978-1-4612-0405-3_4.
- Taylor N, Kolman J, Miller G. Heterodimers of the Zebra and Fos Basic Domains Bind DNA with the Specificity of Zebra. Experimental Biology And Medicine 1991, 99-103. DOI: 10.1007/978-1-4612-0405-3_15.
- Gradoville L, Grogan E, Taylor N, Miller G. Differences in the extent of activation of Epstein-Barr virus replicative gene expression among four nonproducer cell lines stably transformed by OriP/BZLF1 plasmids. Virology 1990, 178: 345-354. PMID: 2171186, DOI: 10.1016/0042-6822(90)90331-k.
- Orlowski R, Polvino-Bodnar M, Hearing J, Miller G. Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies. Virology 1990, 176: 638-642. PMID: 2161154, DOI: 10.1016/0042-6822(90)90036-q.
- Orlowski R, Miller G. Topological Effects of EBNA 1 on oriP. Advances In Experimental Medicine And Biology 1990, 278: 115-124. PMID: 1963028, DOI: 10.1007/978-1-4684-5853-4_12.
- Miller G, Talyor N, Countryman J, Rooney C, Katz D, Kolman J, Jenson H, Grogan E, Gradoville L. Role of The Zebra Protein in the Switch Between Epstein-Barr Virus Latency and Replication. Experimental Biology And Medicine 1989, 17-35. DOI: 10.1007/978-1-4612-4508-7_2.
- Jenson H, Miller G. Polymorphisms of the region of the Epstein-Barr virus genome which disrupts latency. Virology 1988, 165: 549-564. PMID: 2841800, DOI: 10.1016/0042-6822(88)90599-5.
- Ho M, Jaffe R, Miller G, Breinig M, Dummer J, Makowka L, Atchison R, Karrer F, Nalesnik M, Starzl T. THE FREQUENCY OF EPSTEIN-BARR VIRUS INFECTION AND ASSOCIATED LYMPHOPROLIFERATIVE SYNDROME AFTER TRANSPLANTATION AND ITS MANIFESTATIONS IN CHILDREN. Transplantation 1988, 45: 719-726. PMID: 2833828, PMCID: PMC2993427, DOI: 10.1097/00007890-198804000-00011.
- Rowe D, Farrell P, Miller G. Novel nuclear antigens recognized by human sera in lymphocytes latently infected by Epstein-Barr virus. Virology 1987, 156: 153-162. PMID: 3027963, DOI: 10.1016/0042-6822(87)90446-6.
- Miller G, Countryman J, Jenson H, Grogan E, Gradoville L. Disruption of Latency by a Fragment of Rearranged EBV DNA: Evidence for Host Cell Regulation. Experimental Biology And Medicine 1987, 197-206. DOI: 10.1007/978-1-4612-4590-2_44.
- Rosenberg N, Hochberg F, Miller G, Kleinschmidt‐DeMasters B. Primary central nervous system lymphoma related to Epstein‐Barr virus in a patient with acquired immune deficiency syndrome. Annals Of Neurology 1986, 20: 98-102. PMID: 3017188, DOI: 10.1002/ana.410200118.
- MILLER G. Animal model for Epstein-Barr lymphoma. Nature 1986, 319: 626-626. PMID: 3005864, DOI: 10.1038/319626c0.
- Andiman W, Katz B, Miller G. Progressive Epstein-Barr Virus Infection. 1986, 276-286. DOI: 10.1007/978-1-4612-4958-0_33.
- Andiman W, Martin K, Rubinstein A, Pahwa S, Eastman R, Katz B, Pitt J, Miller G. OPPORTUNISTIC LYMPHOPROLIFERATIONS ASSOCIATED WITH EPSTEIN-BARR VIRAL DNA IN INFANTS AND CHILDREN WITH AIDS. The Lancet 1985, 326: 1390-1393. DOI: 10.1016/s0140-6736(85)92557-7.
- Rowe D, Heston L, Metlay J, Miller G. Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 7429-7433. PMID: 2997790, PMCID: PMC391358, DOI: 10.1073/pnas.82.21.7429.
- Miller G, Sugden B. An identification of a transforming region of Epstein-Barr viral DNA cannot be confirmed. Virology 1985, 143: 478-484. PMID: 2998023, DOI: 10.1016/0042-6822(85)90387-3.
- Katz B, Andiman W, Miller G. 1119 INFECTION WITH MULTIPLE EB VIRUS (EBV) GENOTYPES IN AN INFANT WITH AIDS AND HIS MOTHER. Pediatric Research 1985, 19: 297-297. DOI: 10.1203/00006450-198504000-01149.
- Miller G, Grogan E, Fischer D, Niederman J, Schooley R, Henle W, Lenoir G, Liu C. Antibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer. New England Journal Of Medicine 1985, 312: 750-755. PMID: 2983211, DOI: 10.1056/nejm198503213121204.
- Schubach W, Miller G, Thomas E. Epstein-Barr Virus Genomes Are Restricted to Secondary Neoplastic Cells Following Bone Marrow Transplantation. Blood 1985, 65: 535-538. DOI: 10.1182/blood.v65.3.535.535.
- Weigel R, Fischer D, Heston L, Miller G. Constitutive expression of Epstein-Barr virus-encoded RNAs and nuclear antigen during latency and after induction of Epstein-Barr virus replication. Journal Of Virology 1985, 53: 254-259. PMID: 2981344, PMCID: PMC255024, DOI: 10.1128/jvi.53.1.254-259.1985.
- Schmidt W, Sue McIntosh L, Miller G, Andiman W, Dwyer J, Lomax K. REVERSAL OF SIGNS AND SYMPTOMS OF ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) WITH PREDNISONE. Pediatric Research 1984, 18: 264-264. DOI: 10.1203/00006450-198404001-01029.
- Miller G, Rabson M, Heston L. Epstein-Barr virus with heterogeneous DNA disrupts latency. Journal Of Virology 1984, 50: 174-182. PMID: 6321789, PMCID: PMC255597, DOI: 10.1128/jvi.50.1.174-182.1984.
- Miller G. Burkitt Lymphoma. 1984, 599-619. DOI: 10.1007/978-1-4684-4727-9_24.
- Miller G. Regions of the EBV genome involved in latency and lymphocyte immortalization. Medical Virology 1984, 30: 107-28. PMID: 6087408.
- Hochberg F, Miller G, Schooley R, Hirsch M, Feorino P, Henle W. Central-Nervous-System Lymphoma Related to Epstein–Barr Virus. New England Journal Of Medicine 1983, 309: 745-748. PMID: 6310394, DOI: 10.1056/nejm198309293091301.
- Rabson M, Heston L, Miller G. Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1983, 80: 2762-2766. PMID: 6302703, PMCID: PMC393908, DOI: 10.1073/pnas.80.9.2762.
- Coope D, von Graevenitz A, Corrales J, Miller G. Tissue Culture Contamination with Nontuberculous Mycobacteria. Microbiology And Immunology 1983, 27: 113-115. PMID: 6865803, DOI: 10.1111/j.1348-0421.1983.tb03563.x.
- Miller G, Heston L, Hoffman G. Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody. Infection And Immunity 1982, 37: 1028-1031. PMID: 6182100, PMCID: PMC347642, DOI: 10.1128/iai.37.3.1028-1031.1982.
- Schubach W, Hackman R, Neiman P, Miller G, Thomas E. A Monoclonal Immunoblastic Sarcoma in Donor Cells Bearing Epstein-Barr Virus Genomes Following Allogeneic Marrow Grafting for Acute Lymphoblastic Leukemia. Blood 1982, 60: 180-187. DOI: 10.1182/blood.v60.1.180.180.
- Miller G. Burkitt Lymphoma. 1982, 599-619. DOI: 10.1007/978-1-4613-3237-4_24.
- Robinson J, Miller G. Biology of Lymphoid Cells Transformed by Epstein—Barr Virus. The Viruses 1982, 151-207. DOI: 10.1007/978-1-4684-4163-5_4.
- Heston L, Rabson M, Brown N, Miller G. New Epstein–Barr virus variants from cellular subclones of P3J-HR-1 Burkitt lymphoma. Nature 1982, 295: 160-163. PMID: 6276755, DOI: 10.1038/295160a0.
- Anvret M, Miller G. Copy number and location of Epstein-Barr viral genomes in neonatal human lymphocytes transformed after separation by size and treatment with mitogens. Virology 1981, 111: 47-55. PMID: 6263010, DOI: 10.1016/0042-6822(81)90652-8.
- Fischer D, Miller G, Gradoville L, Heston L, Weststrate M, Maris W, Wright J, Brandsma J, Summers W. Genome of a mononucleosis epstein-barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates. Cell 1981, 24: 543-553. PMID: 6263500, DOI: 10.1016/0092-8674(81)90345-7.
- Miller G, Grogan E, Heston L, Robinson J, Smith D. Epstein-Barr Viral DNA: Infectivity for Human Placental Cells. Science 1981, 212: 452-455. PMID: 6259735, DOI: 10.1126/science.6259735.
- Robinson J, Brown N, Andiman W, Halliday K, Francke U, Robert M, Andersson-Anvret M, Horstmann D, Miller G. Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus. New England Journal Of Medicine 1980, 302: 1293-1297. PMID: 6245364, DOI: 10.1056/nejm198006053022306.
- Morgan DG, Miller G, Niederman J, Smith HW, Dowaliby JM. SITE OF EPSTEIN-BARR VIRUS REPLICATION IN THE OROPHARYNX. The Lancet 1979, 314: 1154-1157. PMID: 91888, DOI: 10.1016/s0140-6736(79)92384-5.
- Coope D, Heston L, Brandsma J, Miller G. Cross-neutralization of infectious mononucleosis and Burkitt lymphoma strains of Epstein-Barr virus with hyperimmune rabbit antisera. The Journal Of Immunology 1979, 123: 232-8. PMID: 221591, DOI: 10.4049/jimmunol.123.1.232.
- Miller G. Experimental Carcinogenicity by the Virus In Vivo. 1979, 351-372. DOI: 10.1007/978-3-642-67236-1_16.
- Henderson E, Heston L, Grogan E, Miller G. Radiobiological Inactivation of Epstein-Barr Virus. Journal Of Virology 1978, 25: 51-59. PMID: 202757, PMCID: PMC353900, DOI: 10.1128/jvi.25.1.51-59.1978.
- Henderson E, Miller G, Robinson J, Heston L. Efficiency of transformation of lymphocytes by Epstein-Barr virus. Virology 1977, 76: 152-163. PMID: 189490, DOI: 10.1016/0042-6822(77)90292-6.
- Niederman J, Miller G, Pearson H, Pagano J, Dowaliby J. Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx. New England Journal Of Medicine 1976, 294: 1355-1359. PMID: 177872, DOI: 10.1056/nejm197606172942501.
- Miller G. Epidemiology of Burkitt Lymphoma. 1976, 481-499. DOI: 10.1007/978-1-4613-3988-5_22.
- Miller G, Robinson J, Heston L, Lipman M. Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection and interference. IARC Scientific Publications 1975, 395-408. PMID: 190145.
- Miller G, Robinson J, Heston L, Lipman M. Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference. Proceedings Of The National Academy Of Sciences Of The United States Of America 1974, 71: 4006-4010. PMID: 4372601, PMCID: PMC434316, DOI: 10.1073/pnas.71.10.4006.
- Siegel N, Strauch B, Andrews L, Miller G, Cook C. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. Pediatric Research 1974, 8: 428-428. DOI: 10.1203/00006450-197404000-00531.
- Strauch B, Siegel N, Andrews L, Miller G. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. The Lancet 1974, 303: 234-237. PMID: 4130246, DOI: 10.1016/s0140-6736(74)92546-x.
- Miller G, Robinson J, Heston L. Immortalizing and nonimmortalizing laboratory strains of Epstein-Barr Virus. Cold Spring Harbor Symposia On Quantitative Biology 1974, 39 Pt 2: 773-81. PMID: 169031, DOI: 10.1101/sqb.1974.039.01.089.
- Miller G, Heston L. Expression of Epstein-Barr viral capsid, complement fixing, and nuclear antigens in stationary and exponential phase cultures. The Yale Journal Of Biology And Medicine 1974, 47: 123-35. PMID: 4372815, PMCID: PMC2596417.
- Shope T, Dechairo D, Miller G. Malignant Lymphoma in Cottontop Marmosets after Inoculation with Epstein-Barr Virus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 2487-2491. PMID: 4354852, PMCID: PMC427039, DOI: 10.1073/pnas.70.9.2487.
- Miller G, Niederman J, Andrews L. Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis. New England Journal Of Medicine 1973, 288: 229-232. PMID: 4345064, DOI: 10.1056/nejm197302012880503.
- Miller G, Lipman M. Release of Infectious Epstein-Barr Virus by Transformed Marmoset Leukocytes. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 190-194. PMID: 4346033, PMCID: PMC433213, DOI: 10.1073/pnas.70.1.190.
- Miller G, Shope T, Heston L, O'Brien R, Schwartz A, Pearson H. Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood. The Journal Of Pediatrics 1972, 80: 932-937. PMID: 4337277, DOI: 10.1016/s0022-3476(72)80004-0.
- Miller G, Shope T, Lisco H, Stitt D, Lipman M. Epstein-Barr Virus: Transformation, Cytopathic Changes, and Viral Antigens in Squirrel Monkey and Marmoset Leukocytes. Proceedings Of The National Academy Of Sciences Of The United States Of America 1972, 69: 383-387. PMID: 4333982, PMCID: PMC426463, DOI: 10.1073/pnas.69.2.383.
- Miller M, Stitt D, Miller G. Epstein-Barr viral antigen in single cell clones of two human leukocytic lines. Journal Of Virology 1970, 6: 699-701. PMID: 4320703, PMCID: PMC376178, DOI: 10.1128/jvi.6.5.699-701.1970.
- Grogan E, Enders J, Miller G. Trypsinized Placental Cell Cultures for the Propagation of Viruses and as “Feeder Layers”. Journal Of Virology 1970, 5: 406-409. PMID: 4314557, PMCID: PMC376018, DOI: 10.1128/jvi.5.3.406-409.1970.
- Miller G, Enders J, Lisco H, Kohn H. Establishment of Lines from Normal Human Blood Leukocytes by Co-cultivation with a Leukocyte Line Derived from a Leukemic Child 1. Experimental Biology And Medicine 1969, 132: 247-252. PMID: 4899209, DOI: 10.3181/00379727-132-34189.
Locations
1
Yale Pediatric Infectious Diseases
Yale New Haven Hospital - West Pavilion
1 Park Street, Fl 2
New Haven, CT 06510
1 of 2
- Yale Pediatric Infectious DiseasesYale New Haven Hospital - West Pavilion1 Park Street, Fl 2New Haven, CT 06510
- Yale Pediatric Infectious DiseaseYale New Haven Hospital20 York StreetNew Haven, CT 06510
1
Yale Pediatric Infectious Diseases
Yale New Haven Hospital - West Pavilion
1 Park Street, Fl 2
New Haven, CT 06510
1 of 2
- Yale Pediatric Infectious DiseasesYale New Haven Hospital - West Pavilion1 Park Street, Fl 2New Haven, CT 06510
- Yale Pediatric Infectious DiseaseYale New Haven Hospital20 York StreetNew Haven, CT 06510