George Goshua, MD, SM, FACP
Hematology
Biography
George Goshua, MD, MSc, FACP, is a physician-scientist who specializes in hematology, diagnosing and treating various blood disorders, such as thrombosis and anemia.
Dr. Goshua runs the first health decision science laboratory focused on hematology-oncology outcomes in the United States. His research has been repeatedly awarded by the leading hematology societies, the NOMIS Foundation, and Science Magazine.
Dr. Goshua is an assistant professor of medicine at Yale School of Medicine.
Titles
- Assistant Professor of Medicine (Hematology)
Education & Training
- SMHarvard School of Public Health, Health Policy & Management (Risk & Decision Science) (2022)
- Clinical Fellow (Hematology-Oncology)Yale School of Medicine (2022)
- MDUniversity of Kentucky College of Medicine (2015)
- BSc (Hon)University of Toronto, Neuroscience & Physiology Double Major, Forest Conservation Minor (2010)
Additional Information
Honors & Recognitions
- Young Physician Scientist Award: American Society for Clinical Investigation (2026)
- Top Reviewer [2023 Calendar Year]: Annals of Internal Medicine (2024)
- NOMIS & Science Young Explorer Award: NOMIS Foundation and Science Magazine (2023)
- Top Reviewer [2022 Calendar Year]: Annals of Internal Medicine (2023)
- 2021 Young Investigator Award: American Journal of Hematology (2022)
- 2021-2022 Bernard G. Forget Scholar: Yale Hematology (2021)
- Junior AΩA (2014): Alpha Omega Alpha Honor Medical Society (2014)
- Gold Humanism Honor Society (2014): Arnold P. Gold Foundation (2014)
Publications
- Wang D, Sra M, Ito S, Ng D, Glaeser-Khan S, Wang D, Hirniak S, Lee A, Cuker A, Goshua G. Cost-effectiveness of first-line IV vs oral iron for iron-deficiency anemia in women with heavy menstrual bleeding. Blood Advances 2026, 10: 1508-1517. PMID: 41504430, PMCID: PMC12952766, DOI: 10.1182/bloodadvances.2025018315.
- Ito S, Xicola R, Sra M, Potnis K, Singh V, Gershkovich P, Stites E, Gibson J, Krumholz H, Llor X, Goshua G. Cost-effectiveness of Lynch Syndrome Screening in Colorectal Cancer: Universal Germline vs Sequential Screening. Clinical Gastroenterology And Hepatology 2025, 23: 2328-2338.e9. PMID: 40315972, PMCID: PMC12354148, DOI: 10.1016/j.cgh.2025.03.006.
- Ito S, Potnis K, Harvey J, Sra M, Bewersdorf J, Bona R, Krumholz H, Cuker A, Pandya A, Goshua G. Cost-effectiveness of prophylactic weekly efanesoctocog alfa versus standard-care factor VIII in patients with severe hemophilia A. Annals Of Internal Medicine 2025, 178: 819-828. PMID: 40258278, PMCID: PMC12170149, DOI: 10.7326/annals-24-02749.
- Wang D, Sra M, Glaeser‐Khan S, Wang D, Moshashaian‐Asl R, Ito S, Cuker A, Goshua G. Cost‐Effectiveness of Ferritin Screening Thresholds for Iron Deficiency in Reproductive‐Age Women. American Journal Of Hematology 2025, 100: 1132-1140. PMID: 40235279, PMCID: PMC12146817, DOI: 10.1002/ajh.27686.
- Goshua G, Calhoun C, Ito S, James L, Luviano A, Krishnamurti L, Pandya A. Distributional Cost-Effectiveness of Equity-Enhancing Gene Therapy in Sickle Cell Disease in the United States. Annals Of Internal Medicine 2023, 176: 779-787. PMID: 37247420, PMCID: PMC10370480, DOI: 10.7326/m22-3272.
- Ito S, Goshua G. Apixaban at Apex? Aligning Drug Pricing With Value in Cancer-Associated Thrombosis. Annals Of Internal Medicine 2022, 176: 125-126. PMID: 36571840, DOI: 10.7326/m22-3404.
- Goshua G, Sinha P, Hendrickson J, Tormey C, Bendapudi PK, Lee AI. Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura. Blood 2020, 137: 969-976. PMID: 33280030, PMCID: PMC7918179, DOI: 10.1182/blood.2020006052.
- Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. The Lancet Haematology 2020, 7: e575-e582. PMID: 32619411, PMCID: PMC7326446, DOI: 10.1016/s2352-3026(20)30216-7.
- Rinaldi K, Ng D, Tadepalli A, Ito S, Goshua G, Wang D. Barriers to effective first-line treatment for women with iron deficiency. Expert Review Of Hematology 2026, ahead-of-print: 1-3. PMID: 42212667, DOI: 10.1080/17474086.2026.2683026.
- Chetlapalli K, Ito S, Ng DQ, Sra MS, Wang D, Krumholz H, Krishnamurti L, Pandya A, Goshua G. Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis. Blood Journal 2026, blood.2025032290. DOI: 10.1182/blood.2025032290.
- Lam B, Ito S, Ryu J, O'Sullivan K, Potnis K, Lu R, Bidikian A, Ng D, Singh R, Deter A, Carfagnini C, Bechara S, Kandula M, Do N, Fillmore N, Freed J, Patell R, La J, Goshua G. JAKPOT Prediction Rule for Erythrocytosis: External Validation and Cost‐Effectiveness Analysis. American Journal Of Hematology 2026 PMID: 42227164, DOI: 10.1002/ajh.70390.
- Chetlapalli K, Ito S, Ng D, Sra M, Wang D, Krumholz H, Krishnamurti L, Pandya A, Goshua G. Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis. Blood 2026 PMID: 42227898, DOI: 10.1182/blood.2025032290.
- Wang D, Sra M, Ng D, Tadepalli A, Rinaldi K, Ito S, Cuker A, Goshua G. Cost-effectiveness of iron deficiency screening in pregnancy across ferritin-based thresholds. Blood Advances 2026 PMID: 42206692, DOI: 10.1182/bloodadvances.2026020143.
- Ito S, Potnis K, Ng D, Patel K, Sra M, Shallis R, Podoltsev N, Kewan T, Stempel J, Mendez L, Huntington S, Stahl M, Zeidan A, Bewersdorf J, Goshua G. Cost-effectiveness of frontline eltrombopag with immunosuppressive therapy for severe aplastic anemia. Blood Red Cells & Iron 2026, 2: 100076. PMID: 42077391, PMCID: PMC13134686, DOI: 10.1016/j.brci.2026.100076.
- Pine A, Butt A, Andreoli L, Knight J, Gerosa M, Cecchi I, Branch D, Lopez-Pedrera R, Belmont H, Kello N, Petri M, Cervera R, Pengo V, Meroni P, Cohen H, Willis R, Bertolaccini M, Goshua G, Gu S, Hwa J, Lee A, Erkan D, Sharda A. Correction: A proteomic map of thromboinflammatory signatures in antiphospholipid syndrome: results from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) registry. Frontiers In Immunology 2026, 17: 1807468. DOI: 10.3389/fimmu.2026.1807468.
- Glaeser-Khan S, Shen Y, Wolbert T, Mukherjee T, Goshua G, Ito S, Alperovich M. "Cost-Effectiveness and Budget Impact of Facial Feminization Surgery". Plastic & Reconstructive Surgery 2026 PMID: 41940840, DOI: 10.1097/prs.0000000000013106.
- Goshua G, Lee A. Thrombopoietin-Receptor Agonists in Chemotherapy-Induced Thrombocytopenia. The New England Journal Of Medicine 2026, 394: 1125-1126. PMID: 41812200, DOI: 10.1056/nejme2517578.
- Pandya A, Zhu J, Luviano A, James L, Goshua G. A threshold inequality aversion parameter (TIAP) approach to interpret distributional cost-effectiveness analysis results. Value In Health 2025, s1098-3015(25)05621-9. PMID: 41093070, PMCID: PMC12684637, DOI: 10.1016/j.jval.2025.09.3064.
Biography
George Goshua, MD, MSc, FACP, is a physician-scientist who specializes in hematology, diagnosing and treating various blood disorders, such as thrombosis and anemia.
Dr. Goshua runs the first health decision science laboratory focused on hematology-oncology outcomes in the United States. His research has been repeatedly awarded by the leading hematology societies, the NOMIS Foundation, and Science Magazine.
Dr. Goshua is an assistant professor of medicine at Yale School of Medicine.
Titles
- Assistant Professor of Medicine (Hematology)
Education & Training
- SMHarvard School of Public Health, Health Policy & Management (Risk & Decision Science) (2022)
- Clinical Fellow (Hematology-Oncology)Yale School of Medicine (2022)
- MDUniversity of Kentucky College of Medicine (2015)
- BSc (Hon)University of Toronto, Neuroscience & Physiology Double Major, Forest Conservation Minor (2010)
Additional Information
Honors & Recognitions
- Young Physician Scientist Award: American Society for Clinical Investigation (2026)
- Top Reviewer [2023 Calendar Year]: Annals of Internal Medicine (2024)
- NOMIS & Science Young Explorer Award: NOMIS Foundation and Science Magazine (2023)
- Top Reviewer [2022 Calendar Year]: Annals of Internal Medicine (2023)
- 2021 Young Investigator Award: American Journal of Hematology (2022)
- 2021-2022 Bernard G. Forget Scholar: Yale Hematology (2021)
- Junior AΩA (2014): Alpha Omega Alpha Honor Medical Society (2014)
- Gold Humanism Honor Society (2014): Arnold P. Gold Foundation (2014)
Publications
- Wang D, Sra M, Ito S, Ng D, Glaeser-Khan S, Wang D, Hirniak S, Lee A, Cuker A, Goshua G. Cost-effectiveness of first-line IV vs oral iron for iron-deficiency anemia in women with heavy menstrual bleeding. Blood Advances 2026, 10: 1508-1517. PMID: 41504430, PMCID: PMC12952766, DOI: 10.1182/bloodadvances.2025018315.
- Ito S, Xicola R, Sra M, Potnis K, Singh V, Gershkovich P, Stites E, Gibson J, Krumholz H, Llor X, Goshua G. Cost-effectiveness of Lynch Syndrome Screening in Colorectal Cancer: Universal Germline vs Sequential Screening. Clinical Gastroenterology And Hepatology 2025, 23: 2328-2338.e9. PMID: 40315972, PMCID: PMC12354148, DOI: 10.1016/j.cgh.2025.03.006.
- Ito S, Potnis K, Harvey J, Sra M, Bewersdorf J, Bona R, Krumholz H, Cuker A, Pandya A, Goshua G. Cost-effectiveness of prophylactic weekly efanesoctocog alfa versus standard-care factor VIII in patients with severe hemophilia A. Annals Of Internal Medicine 2025, 178: 819-828. PMID: 40258278, PMCID: PMC12170149, DOI: 10.7326/annals-24-02749.
- Wang D, Sra M, Glaeser‐Khan S, Wang D, Moshashaian‐Asl R, Ito S, Cuker A, Goshua G. Cost‐Effectiveness of Ferritin Screening Thresholds for Iron Deficiency in Reproductive‐Age Women. American Journal Of Hematology 2025, 100: 1132-1140. PMID: 40235279, PMCID: PMC12146817, DOI: 10.1002/ajh.27686.
- Goshua G, Calhoun C, Ito S, James L, Luviano A, Krishnamurti L, Pandya A. Distributional Cost-Effectiveness of Equity-Enhancing Gene Therapy in Sickle Cell Disease in the United States. Annals Of Internal Medicine 2023, 176: 779-787. PMID: 37247420, PMCID: PMC10370480, DOI: 10.7326/m22-3272.
- Ito S, Goshua G. Apixaban at Apex? Aligning Drug Pricing With Value in Cancer-Associated Thrombosis. Annals Of Internal Medicine 2022, 176: 125-126. PMID: 36571840, DOI: 10.7326/m22-3404.
- Goshua G, Sinha P, Hendrickson J, Tormey C, Bendapudi PK, Lee AI. Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura. Blood 2020, 137: 969-976. PMID: 33280030, PMCID: PMC7918179, DOI: 10.1182/blood.2020006052.
- Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. The Lancet Haematology 2020, 7: e575-e582. PMID: 32619411, PMCID: PMC7326446, DOI: 10.1016/s2352-3026(20)30216-7.
- Rinaldi K, Ng D, Tadepalli A, Ito S, Goshua G, Wang D. Barriers to effective first-line treatment for women with iron deficiency. Expert Review Of Hematology 2026, ahead-of-print: 1-3. PMID: 42212667, DOI: 10.1080/17474086.2026.2683026.
- Chetlapalli K, Ito S, Ng DQ, Sra MS, Wang D, Krumholz H, Krishnamurti L, Pandya A, Goshua G. Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis. Blood Journal 2026, blood.2025032290. DOI: 10.1182/blood.2025032290.
- Lam B, Ito S, Ryu J, O'Sullivan K, Potnis K, Lu R, Bidikian A, Ng D, Singh R, Deter A, Carfagnini C, Bechara S, Kandula M, Do N, Fillmore N, Freed J, Patell R, La J, Goshua G. JAKPOT Prediction Rule for Erythrocytosis: External Validation and Cost‐Effectiveness Analysis. American Journal Of Hematology 2026 PMID: 42227164, DOI: 10.1002/ajh.70390.
- Chetlapalli K, Ito S, Ng D, Sra M, Wang D, Krumholz H, Krishnamurti L, Pandya A, Goshua G. Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis. Blood 2026 PMID: 42227898, DOI: 10.1182/blood.2025032290.
- Wang D, Sra M, Ng D, Tadepalli A, Rinaldi K, Ito S, Cuker A, Goshua G. Cost-effectiveness of iron deficiency screening in pregnancy across ferritin-based thresholds. Blood Advances 2026 PMID: 42206692, DOI: 10.1182/bloodadvances.2026020143.
- Ito S, Potnis K, Ng D, Patel K, Sra M, Shallis R, Podoltsev N, Kewan T, Stempel J, Mendez L, Huntington S, Stahl M, Zeidan A, Bewersdorf J, Goshua G. Cost-effectiveness of frontline eltrombopag with immunosuppressive therapy for severe aplastic anemia. Blood Red Cells & Iron 2026, 2: 100076. PMID: 42077391, PMCID: PMC13134686, DOI: 10.1016/j.brci.2026.100076.
- Pine A, Butt A, Andreoli L, Knight J, Gerosa M, Cecchi I, Branch D, Lopez-Pedrera R, Belmont H, Kello N, Petri M, Cervera R, Pengo V, Meroni P, Cohen H, Willis R, Bertolaccini M, Goshua G, Gu S, Hwa J, Lee A, Erkan D, Sharda A. Correction: A proteomic map of thromboinflammatory signatures in antiphospholipid syndrome: results from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) registry. Frontiers In Immunology 2026, 17: 1807468. DOI: 10.3389/fimmu.2026.1807468.
- Glaeser-Khan S, Shen Y, Wolbert T, Mukherjee T, Goshua G, Ito S, Alperovich M. "Cost-Effectiveness and Budget Impact of Facial Feminization Surgery". Plastic & Reconstructive Surgery 2026 PMID: 41940840, DOI: 10.1097/prs.0000000000013106.
- Goshua G, Lee A. Thrombopoietin-Receptor Agonists in Chemotherapy-Induced Thrombocytopenia. The New England Journal Of Medicine 2026, 394: 1125-1126. PMID: 41812200, DOI: 10.1056/nejme2517578.
- Pandya A, Zhu J, Luviano A, James L, Goshua G. A threshold inequality aversion parameter (TIAP) approach to interpret distributional cost-effectiveness analysis results. Value In Health 2025, s1098-3015(25)05621-9. PMID: 41093070, PMCID: PMC12684637, DOI: 10.1016/j.jval.2025.09.3064.