Genta Ishikawa, MD, MPH
Internal Medicine, Pulmonary Critical Care , Critical Care Medicine
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Internal Medicine, Pulmonary Disease
, and Critical Care Medicine (Internal Medicine)
Titles
- Instructor
Education & Training
- Postdoctoral FellowYale University (2023)
- Clinical FellowMount Sinai Hospital (2020)
- ResidentMount Sinai Beth Israel (2017)
- MPHEmory University, Rollins School of Public Health (2017)
- InternMount Sinai Beth Israel (2015)
- Clinical FellowSt. Luke's International Hospital (2013)
- ResidentJuntendo University Hospital (2009)
- MDHokkaido University, School of Medicine (2007)
Languages Spoken
- English
- 日本語 (Japanese)
Additional Information
Honors & Recognitions
- Yale's Janeway Society: Yale School of Medicine (2023)
- Yale Physician-Scientist Development Award (KL-2 career development award): Yale Center for Clinical Investigation (2023)
- Wit Family Distinguished Scholar in Inflammation Science: Yale Center for Clinical Investigation (2023)
- Pulmonary Fibrosis Foundation Scholar Grant: Pulmonary Fibrosis Foundation (2022)
- Stony Wold-Herbert Fellowship Grant: Stony Wold-Herbert Fund (2019)
- ATS Fellows Track Symposium Award: American Thoracic Society (2019)
- N Program Scholarship Award: Tokio Marine Nichido (2014)
- Travel Award: Japanese Respiratory Society (2012)
Board Certifications
- AB of Imaging Informatics, Critical Care Medicine (Internal Medicine) (2020)
- AB of Internal Medicine, Pulmonary Disease (2019)
- AB of Internal Medicine, Internal Medicine (2017)
Publications
- LEE C, TRUJILLO G, REGUEIRO-REN A, LIU C, HU B, SUN Y, KHOURY J, KHOURY J, AHANGARI F, ISHIKAWA G, WALIA A, PIVARNIK T, YU S, WOO S, FIORINI V, MCGOVERN J, AL JUMAILY K, SUN H, PENG X, ANTIN-OZERKIS D, SAULER M, KAMINSKI N, HERZOG E. INTERACTIONS BETWEEN MITOCHONDRIAL DNA AND TOLL-LIKE RECEPTOR 9 MEDIATES PULMONARY FIBROSIS. CHEST Journal 2024, 166: a3384-a3386. DOI: 10.1016/j.chest.2024.06.2020.
- Trujillo G, Regueiro-Ren A, Liu C, Hu B, Sun Y, Ahangari F, Fiorini V, Ishikawa G, Al Jumaily K, Khoury J, McGovern J, Lee C, Peng X, Pivarnik T, Sun H, Walia A, Woo S, Yu S, Antin-Ozerkis D, Sauler M, Kaminski N, Herzog E, Ryu C. Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2024 PMID: 39189851, DOI: 10.1164/rccm.202401-0065oc.
- Unterman A, Zhao A, Neumark N, Schupp J, Ahangari F, Cosme C, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida T, Gomez J, Herazo-Maya J, Dela Cruz C, Herzog E, Kaminski N. Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2024, 210: 484-496. PMID: 38717443, PMCID: PMC11351796, DOI: 10.1164/rccm.202306-0979oc.
- Ishikawa G, Peng X, Mcgovern J, Ghincea A, Saber T, Sun H, Sauler M, Ryu C, Herzog E. Role of Noradrenaline and Macrophage Dynamics in Pulmonary Fibrosis. 2024, a5206-a5206. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5206.
- Essayas H, Kim J, Mcgovern J, Peng X, Cai Y, Ishikawa G, Herzog E, Dela Cruz C, Ryu C, Sharma L. Toll-like Receptor-9 Activation Promotes Persistent Inflammation in the Lung During Influenza Infection. 2023, a5608-a5608. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5608.
- Ishikawa G, Peng X, McGovern J, Woo S, Perry C, Liu A, Yu S, Ghincea A, Kishchanka A, Fiorini V, Hu B, Sun Y, Sun H, Ryu C, Herzog E. α1 Adrenoreceptor antagonism mitigates extracellular mitochondrial DNA accumulation in lung fibrosis models and in patients with idiopathic pulmonary fibrosis. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2023, 324: l639-l651. PMID: 36648147, PMCID: PMC10110730, DOI: 10.1152/ajplung.00119.2022.
- Ishikawa G, Herzog EL. PTX3 in Granuloma Formation and Sarcoidosis: Helping Macrophages Accept a “Complement”. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 1064-1065. PMID: 35820078, PMCID: PMC9704837, DOI: 10.1164/rccm.202207-1277ed.
- Ishikawa G, Liu A, Herzog EL. Evolving Perspectives on Innate Immune Mechanisms of IPF. Frontiers In Molecular Biosciences 2021, 8: 676569. PMID: 34434962, PMCID: PMC8381017, DOI: 10.3389/fmolb.2021.676569.
- Minasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Liu A, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog EL, Dela Cruz CS, Ryu C. Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2021, 320: l1137-l1146. PMID: 33851886, PMCID: PMC8285626, DOI: 10.1152/ajplung.00575.2020.
- Gao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. Macrophage-derived netrin-1 drives adrenergic nerve–associated lung fibrosis. Journal Of Clinical Investigation 2021, 131: e136542. PMID: 33393489, PMCID: PMC7773383, DOI: 10.1172/jci136542.
- Ishikawa G, Fujiwara N, Hirschfield H, Varricchio L, Hoshida Y, Barosi G, Rosti V, Padilla M, Mazzarini M, Friedman SL, Hoffman R, Migliaccio AR. Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia. Experimental Hematology 2019, 79: 16-25.e3. PMID: 31678370, PMCID: PMC6910948, DOI: 10.1016/j.exphem.2019.10.001.
- Ishikawa G, Dua S, Mathur A, Acquah SO, Salvatore M, Beasley MB, Padilla ML. Concomitant Interstitial Lung Disease with Psoriasis. Canadian Respiratory Journal 2019, 2019: 5919304. PMID: 31534591, PMCID: PMC6732645, DOI: 10.1155/2019/5919304.
- Salvatore M, Ishikawa G, Padilla M. Is It Idiopathic Pulmonary Fibrosis or Not? The Journal Of The American Board Of Family Medicine 2018, 31: 151-162. PMID: 29330249, DOI: 10.3122/jabfm.2018.01.170288.
- Ishikawa G, Acquah SO, Salvatore M, Padilla ML. Elevated serum D-dimer level is associated with an increased risk of acute exacerbation in interstitial lung disease. Respiratory Medicine 2017, 128: 78-84. PMID: 28610674, DOI: 10.1016/j.rmed.2017.05.009.
Departments and Programs
Titles
- Instructor
Education & Training
- Postdoctoral FellowYale University (2023)
- Clinical FellowMount Sinai Hospital (2020)
- ResidentMount Sinai Beth Israel (2017)
- MPHEmory University, Rollins School of Public Health (2017)
- InternMount Sinai Beth Israel (2015)
- Clinical FellowSt. Luke's International Hospital (2013)
- ResidentJuntendo University Hospital (2009)
- MDHokkaido University, School of Medicine (2007)
Languages Spoken
- English
- 日本語 (Japanese)
Additional Information
Honors & Recognitions
- Yale's Janeway Society: Yale School of Medicine (2023)
- Yale Physician-Scientist Development Award (KL-2 career development award): Yale Center for Clinical Investigation (2023)
- Wit Family Distinguished Scholar in Inflammation Science: Yale Center for Clinical Investigation (2023)
- Pulmonary Fibrosis Foundation Scholar Grant: Pulmonary Fibrosis Foundation (2022)
- Stony Wold-Herbert Fellowship Grant: Stony Wold-Herbert Fund (2019)
- ATS Fellows Track Symposium Award: American Thoracic Society (2019)
- N Program Scholarship Award: Tokio Marine Nichido (2014)
- Travel Award: Japanese Respiratory Society (2012)
Board Certifications
- AB of Imaging Informatics, Critical Care Medicine (Internal Medicine) (2020)
- AB of Internal Medicine, Pulmonary Disease (2019)
- AB of Internal Medicine, Internal Medicine (2017)
Publications
- LEE C, TRUJILLO G, REGUEIRO-REN A, LIU C, HU B, SUN Y, KHOURY J, KHOURY J, AHANGARI F, ISHIKAWA G, WALIA A, PIVARNIK T, YU S, WOO S, FIORINI V, MCGOVERN J, AL JUMAILY K, SUN H, PENG X, ANTIN-OZERKIS D, SAULER M, KAMINSKI N, HERZOG E. INTERACTIONS BETWEEN MITOCHONDRIAL DNA AND TOLL-LIKE RECEPTOR 9 MEDIATES PULMONARY FIBROSIS. CHEST Journal 2024, 166: a3384-a3386. DOI: 10.1016/j.chest.2024.06.2020.
- Trujillo G, Regueiro-Ren A, Liu C, Hu B, Sun Y, Ahangari F, Fiorini V, Ishikawa G, Al Jumaily K, Khoury J, McGovern J, Lee C, Peng X, Pivarnik T, Sun H, Walia A, Woo S, Yu S, Antin-Ozerkis D, Sauler M, Kaminski N, Herzog E, Ryu C. Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2024 PMID: 39189851, DOI: 10.1164/rccm.202401-0065oc.
- Unterman A, Zhao A, Neumark N, Schupp J, Ahangari F, Cosme C, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida T, Gomez J, Herazo-Maya J, Dela Cruz C, Herzog E, Kaminski N. Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2024, 210: 484-496. PMID: 38717443, PMCID: PMC11351796, DOI: 10.1164/rccm.202306-0979oc.
- Ishikawa G, Peng X, Mcgovern J, Ghincea A, Saber T, Sun H, Sauler M, Ryu C, Herzog E. Role of Noradrenaline and Macrophage Dynamics in Pulmonary Fibrosis. 2024, a5206-a5206. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5206.
- Essayas H, Kim J, Mcgovern J, Peng X, Cai Y, Ishikawa G, Herzog E, Dela Cruz C, Ryu C, Sharma L. Toll-like Receptor-9 Activation Promotes Persistent Inflammation in the Lung During Influenza Infection. 2023, a5608-a5608. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5608.
- Ishikawa G, Peng X, McGovern J, Woo S, Perry C, Liu A, Yu S, Ghincea A, Kishchanka A, Fiorini V, Hu B, Sun Y, Sun H, Ryu C, Herzog E. α1 Adrenoreceptor antagonism mitigates extracellular mitochondrial DNA accumulation in lung fibrosis models and in patients with idiopathic pulmonary fibrosis. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2023, 324: l639-l651. PMID: 36648147, PMCID: PMC10110730, DOI: 10.1152/ajplung.00119.2022.
- Ishikawa G, Herzog EL. PTX3 in Granuloma Formation and Sarcoidosis: Helping Macrophages Accept a “Complement”. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 1064-1065. PMID: 35820078, PMCID: PMC9704837, DOI: 10.1164/rccm.202207-1277ed.
- Ishikawa G, Liu A, Herzog EL. Evolving Perspectives on Innate Immune Mechanisms of IPF. Frontiers In Molecular Biosciences 2021, 8: 676569. PMID: 34434962, PMCID: PMC8381017, DOI: 10.3389/fmolb.2021.676569.
- Minasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Liu A, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog EL, Dela Cruz CS, Ryu C. Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2021, 320: l1137-l1146. PMID: 33851886, PMCID: PMC8285626, DOI: 10.1152/ajplung.00575.2020.
- Gao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. Macrophage-derived netrin-1 drives adrenergic nerve–associated lung fibrosis. Journal Of Clinical Investigation 2021, 131: e136542. PMID: 33393489, PMCID: PMC7773383, DOI: 10.1172/jci136542.
- Ishikawa G, Fujiwara N, Hirschfield H, Varricchio L, Hoshida Y, Barosi G, Rosti V, Padilla M, Mazzarini M, Friedman SL, Hoffman R, Migliaccio AR. Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia. Experimental Hematology 2019, 79: 16-25.e3. PMID: 31678370, PMCID: PMC6910948, DOI: 10.1016/j.exphem.2019.10.001.
- Ishikawa G, Dua S, Mathur A, Acquah SO, Salvatore M, Beasley MB, Padilla ML. Concomitant Interstitial Lung Disease with Psoriasis. Canadian Respiratory Journal 2019, 2019: 5919304. PMID: 31534591, PMCID: PMC6732645, DOI: 10.1155/2019/5919304.
- Salvatore M, Ishikawa G, Padilla M. Is It Idiopathic Pulmonary Fibrosis or Not? The Journal Of The American Board Of Family Medicine 2018, 31: 151-162. PMID: 29330249, DOI: 10.3122/jabfm.2018.01.170288.
- Ishikawa G, Acquah SO, Salvatore M, Padilla ML. Elevated serum D-dimer level is associated with an increased risk of acute exacerbation in interstitial lung disease. Respiratory Medicine 2017, 128: 78-84. PMID: 28610674, DOI: 10.1016/j.rmed.2017.05.009.
Departments and Programs