Edward Manning, MD, PhD
Internal Medicine, Pulmonary Critical Care
Biography
Edward Manning, MD, PhD, is a specialist in pulmonary and critical care medicine who treats people with lung diseases and breathing challenges. He diagnoses and manages conditions such as persistent shortness of breath and chronic lung disorders, using a range of approaches to improve patients’ well-being.
As an assistant professor of medicine (pulmonary) at Yale School of Medicine, Dr. Manning studies how prolonged low oxygen levels and aging can alter the blood vessels of the lungs and affect heart function. His work aims to develop strategies that support long-term cardiopulmonary health.
Dr. Manning pursued his medical training at Albert Einstein College of Medicine, completed a residency at the Hospital of the University of Pennsylvania, and gained further expertise through a fellowship in pulmonary and critical care medicine at Yale School of Medicine.
Titles
- Assistant Professor of Medicine (Pulmonary)
Education & Training
- Pulmonary, Critical Care FellowshipYale School of Medicine (2020)
- ResidencyHospital of the University of Pennsylvania (2016)
- MDAlbert Einstein College of Medicine of Yeshiva University (2014)
- PhDAlbert Einstein College of Medicine of Yeshiva University, Biophysics (2014)
- MAHunter College - City University of New York, Physics (2005)
- MPATroy State University, Public Policy (2000)
- BSUniversity of Albany - State University of New York, Physics/Russian (1994)
Additional Information
Honors & Recognitions
- Butler-Williams Scholar: National Institute on Aging (2021)
- Pepper Scholar: Yale Pepper Center (2021)
- Young Physician Leadership Conference: Connecticut State Medical Society (2021)
- Fellow of the Year: Internal Medicine Residency Program, Yale School of Medicine (2017)
- Ger Award in Anatomy: Albert Einstein College of Medicine (2014)
- Dean's Recognition: Albert Einstein College of Medicine (2014)
Board Certifications
- National Board of Echocardiography, Adult Echocardiography (2021)
Professional Service
- Clinician-Scientists Transdisciplinary Aging Research Coordinating Center (2022 - 2023): Committee Member
- AMSUS The Society for Federal Health Professionals (2013 - 2020): Reviewer
Publications
- Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, Murphy T, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey J. Stiffening of the human proximal pulmonary artery with increasing age. Physiological Reports 2024, 12: e16090. PMID: 38884325, PMCID: PMC11181131, DOI: 10.14814/phy2.16090.
- Harris Z, Sun Y, Korde A, Hu B, Sharma L, Manning E, Joerns J, Clark B, Stanley G, Shin H, Placek L, Unutmaz D, Chun H, Sauler M, Rajagopalan G, Zhang X, Wang H, Kang M, Koff J. Epidermal Growth Factor Receptor Regulates Beclin-1 in Hyperoxia-Induced Lung Injury. 2024, a6841-a6841. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6841.
- Khoury J, Ahangari F, Manning E, Justet A, barnthaler T, Adams T, Necola F, Alysandratos K, Beermann M, Kotton D, Kaminski N. Profibrotic Role of GPR87 in Pulmonary Fibrosis. 2024, a5183-a5183. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5183.
- Ramachandra A, Jiang B, Jennings I, Manning E, Humphrey J. Remodeling of Murine Branch Pulmonary Arteries Under Chronic Hypoxia and Short-Term Normoxic Recovery. Journal Of Biomechanical Engineering 2024, 146 PMID: 38421341, DOI: 10.1115/1.4064967.
- Weil K, Baumann V, Brown B, Nadeau R, Hrdlicka H, Gerstenhaber B, Rosenblum D, Manning E. Guillain-Barre in the long-term acute care hospital setting: Ventilation does not prolong stay. Journal Of Mechanical Ventilation 2024, 5: 13-19. DOI: 10.53097/jmv.10094.
- Bärnthaler T, Ramachandra A, Ebanks S, Guerrera N, Sharma L, Dela Cruz C, Humphrey J, Manning E. Developmental changes in lung function of mice are independent of sex as a biological variable. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2024, 326: l627-l637. PMID: 38375577, PMCID: PMC11380952, DOI: 10.1152/ajplung.00120.2023.
- Schupp J, Manning E, Chioccioli M, Kamp J, Christian L, Ryu C, Herzog E, Kühnel M, Prasse A, Kaminski N, Jonigk D, Homer R, Neubert L, Ius F, stringJustet A, Hariri L, Seeliger B, Welte T, Knipe R, Gottlieb J. Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 819-822. PMID: 37552025, PMCID: PMC10563189, DOI: 10.1164/rccm.202303-0544le.
- Kim S, Adams T, Hu Q, Shin H, Chae G, Lee S, Sharma L, Kwon H, Lee F, Park H, Huh W, Manning E, Kaminski N, Sauler M, Chen L, Song J, Kim T, Kang M. VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis. American Journal Of Respiratory Cell And Molecular Biology 2023, 69: 22-33. PMID: 36450109, PMCID: PMC10324045, DOI: 10.1165/rcmb.2022-0219oc.
- Yuan Y, Khoury J, Ramachandra A, Singh I, Tellides G, Humphrey J, Kaminski N, Manning E. The Extracellular Matrix of the Human Proximal Pulmonary Artery Regulates Gene Expression of Resident Cells Responsible for Remodeling During Aging. 2023, a2680-a2680. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2680.
- Manning E, Ramachandra A, Cavinato C, Schupp J, Justet A, Lee P, Heerdt P, Singh I, Murphy T, Gill T, Tellides G, Kaminski N, Humphrey J. Age-related Changes in Structure, Function, and Transcriptomics of the Human Proximal Pulmonary Artery. 2023, a4656-a4656. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4656.
- Manning E, Ramachandra A, Cavinato C, Lee P, Heerdt P, Singh I, Tellides G, Kaminski N, Humphrey J. Pulmonary Hypertension-related Changes in Structure and Function of the Human Proximal Pulmonary Artery. 2023, a6133-a6133. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6133.
- Weil K, Baumann V, Brown B, Jano L, Nadeau R, Rosenblum D, Gerstenhaber B, Manning E. Patients With Acute Guillain-Barre Syndrome in Long-Term Acute Care. 2023, a3926-a3926. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3926.
- Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E. Prognostic variables and decannulation of tracheostomy in the long-term acute care environment: a case for clinician-driven decision-making. Journal Of Mechanical Ventilation 2023, 4: 1-8. PMID: 37426175, PMCID: PMC10328447, DOI: 10.53097/jmv.10069.
- Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E. The association between beta-natriuretic peptide (BNP) serum levels and liberation from mechanical ventilation. Pulmonary Medicine & Respiratory Research 2023, 9: 1-3. PMID: 38188724, PMCID: PMC10768849, DOI: 10.24966/pmrr-0177/100075.
- Harris ZM, Sun Y, Joerns J, Clark B, Hu B, Korde A, Sharma L, Shin HJ, Manning EP, Placek L, Unutmaz D, Stanley G, Chun H, Sauler M, Rajagopalan G, Zhang X, Kang MJ, Koff JL. Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia‐Induced Lung Injury. Oxidative Medicine And Cellular Longevity 2022, 2022: 9518592. PMID: 36193076, PMCID: PMC9526641, DOI: 10.1155/2022/9518592.
- Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E. Prognostic Variables and Decannulation of Tracheostomy in the Long-Term Acute Care Hospital Environment: A Case for Clinician-Driven Decision-Making. 2022, a4305-a4305. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4305.
- Ramachandra AB, Mikush N, Sauler M, Humphrey JD, Manning EP. Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice. Journal Of Biomechanical Engineering 2022, 144 PMID: 35171214, PMCID: PMC8990734, DOI: 10.1115/1.4053873.
- Manning EP, Ramachandra AB, Schupp JC, Cavinato C, Raredon MSB, Bärnthaler T, Cosme C, Singh I, Tellides G, Kaminski N, Humphrey JD. Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data. Frontiers In Physiology 2021, 12: 726253. PMID: 34594238, PMCID: PMC8478173, DOI: 10.3389/fphys.2021.726253.
- Schupp JC, Adams TS, Cosme C, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe’er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. Circulation 2021, 144: 286-302. PMID: 34030460, PMCID: PMC8300155, DOI: 10.1161/circulationaha.120.052318.
- Manning EP, Stephens MD, Dufresne S, Silver B, Gerbarg P, Gerbarg Z, Dela Cruz CS, Sharma L. Disinfection of Pseudomonas aeruginosa from N95 respirators with ozone: a pilot study. BMJ Open Respiratory Research 2021, 8: e000781. PMID: 33431507, PMCID: PMC7802653, DOI: 10.1136/bmjresp-2020-000781.
- Centor RM, Manning EP. Web Exclusive. Annals On Call - Are VA Patients Different? Annals Of Internal Medicine 2020, 172: oc1. PMID: 32066167, DOI: 10.7326/a19-0024.
- Manning EP. A Veteran-Centric Model of Care: Crossing the Cultural Divide. Annals Of Internal Medicine 2019, 171: 843-844. PMID: 31658471, PMCID: PMC7188555, DOI: 10.7326/m19-1264.
- Ryu C, Brandsdorfer C, Adams T, Hu B, Kelleher DW, Yaggi M, Manning EP, Walia A, Reeves B, Pan H, Winkler J, Minasyan M, Dela Cruz CS, Kaminski N, Gulati M, Herzog EL. Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis. European Respiratory Journal 2019, 54: 1801762. PMID: 31273041, PMCID: PMC8088542, DOI: 10.1183/13993003.01762-2018.
- Manning EP, Losier A, Emeagwali N, Ryu C, Honiden S. New Applications of Old Drugs as Novel Therapies in Idiopathic Pulmonary Fibrosis. Metformin, Hydroxychloroquine, and Thyroid Hormone. American Journal Of Respiratory And Critical Care Medicine 2019, 199: 1561-1563. PMID: 30822095, PMCID: PMC7051474, DOI: 10.1164/rccm.201809-1700rr.
- Hakim A, Bazan IS, Sanogo ML, Manning EP, Pollak JS, Chupp GL. Pulmonary artery pseudoaneurysm causing massive hemoptysis in hyperimmunoglobulin E syndrome: a case report. BMC Pulmonary Medicine 2019, 19: 34. PMID: 30736787, PMCID: PMC6368789, DOI: 10.1186/s12890-019-0797-7.
- Manning EP, Mishall PL, Weidmann MD, Flax H, Lan S, Erlich M, Burton WB, Olson TR, Downie SA. Early and prolonged opportunities to practice suturing increases medical student comfort with suturing during clerkships: Suturing during cadaver dissection. Anatomical Sciences Education 2018, 11: 605-612. PMID: 29603672, PMCID: PMC6165707, DOI: 10.1002/ase.1785.
- Is Repeating Direct-Fluorescent Antibody Testing for Influenza Beneficial?Manning EP, Moskowitz CS. Connecticut Medicine 2018; 82:487-488.
- Manning EP. Central Nervous System Oxygen Toxicity and Hyperbaric Oxygen Seizures. Aerospace Medicine And Human Performance 2016, 87: 477-486. PMID: 27099087, PMCID: PMC7092644, DOI: 10.3357/amhp.4463.2016.
- Manning EP, Vattipallly V, Niazi M, Shah A. PhytobezoarInduced Small Bowel Obstruction in a Young Male with Virgin Abdomen. Journal Of Gastrointestinal & Digestive System 2015, 05: 266. PMID: 29795770, PMCID: PMC5962263, DOI: 10.4172/2161-069x.1000266.
- Manning EP, Laskowski LK, Nelson LS, Touger M. Young Woman With Epigastric Pain and Vomiting. Annals Of Emergency Medicine 2014, 64: 330-333. PMID: 25149968, PMCID: PMC4203436, DOI: 10.1016/j.annemergmed.2013.12.022.
- Manning E, Lehman S, Schwartz S, Tardiff J. Computational Prediction and Experimental Verification of Differential Calcium Affinity in Thin Filament Mutants Known to Cause Hypertrophic Cardiomyopathy. Biophysical Journal 2014, 106: 349a. DOI: 10.1016/j.bpj.2013.11.1985.
- Manning EP, Tardiff JC, Schwartz SD. Molecular Effects of Familial Hypertrophic Cardiomyopathy-Related Mutations in the TNT1 Domain of cTnT. Journal Of Molecular Biology 2012, 421: 54-66. PMID: 22579624, PMCID: PMC3545441, DOI: 10.1016/j.jmb.2012.05.008.
- Manning EP, Guinto PJ, Tardiff JC. Correlation of Molecular and Functional Effects of Mutations in Cardiac Troponin T Linked to Familial Hypertrophic Cardiomyopathy. Journal Of Biological Chemistry 2012, 287: 14515-14523. PMID: 22334656, PMCID: PMC3340284, DOI: 10.1074/jbc.m111.257436.
- Manning EP, Tardiff JC, Schwartz SD. A Model of Calcium Activation of the Cardiac Thin Filament. Biochemistry 2011, 50: 7405-7413. PMID: 21797264, PMCID: PMC3165030, DOI: 10.1021/bi200506k.
- Manning E, Tardiff J, Schwartz S. Computational Modeling of Cardiac Troponin Dynamics: Elucidating a Regulatory Mechanism for Calcium Activation of the Thin Filament. Biophysical Journal 2011, 100: 225a. DOI: 10.1016/j.bpj.2010.12.1440.
- Guinto P, Manning E, Moore R, Schwartz S, Tardiff J. Structural and Functional Characterization of Cardiac Troponin T Mutations in the TNT1 Domain That Cause Familial Hypertrophic Cardiomyopathy. Biophysical Journal 2009, 96: 499a. DOI: 10.1016/j.bpj.2008.12.2575.
- Guinto PJ, Manning EP, Schwartz SD, Tardiff JC. COMPUTATIONAL CHARACTERIZATION OF MUTATIONS IN CARDIAC TROPONIN T KNOWN TO CAUSE FAMILIAL HYPERTROPHIC CARDIOMYOPATHY. Journal Of Computational Biophysics And Chemistry 2007, 6: 413-419. PMID: 26500385, PMCID: PMC4617307, DOI: 10.1142/s0219633607003271.
- Manning EP, Wilson B. Dehydration in extreme temperatures while conducting stability and support operations in a combat zone. Military Medicine 2007, 172: 972-6. PMID: 17937362, DOI: 10.7205/milmed.172.9.972.
- Nuraje N, Su K, Haboosheh A, Samson J, Manning EP, Yang NL, Matsui H. Room Temperature Synthesis of Ferroelectric Barium Titanate Nanoparticles Using Peptide Nanorings as Templates. Advanced Materials (Deerfield Beach, Fla.) 2006, 18: 807-811. PMID: 31031545, PMCID: PMC6482853, DOI: 10.1002/adma.200501340.
Departments and Programs
Biography
Edward Manning, MD, PhD, is a specialist in pulmonary and critical care medicine who treats people with lung diseases and breathing challenges. He diagnoses and manages conditions such as persistent shortness of breath and chronic lung disorders, using a range of approaches to improve patients’ well-being.
As an assistant professor of medicine (pulmonary) at Yale School of Medicine, Dr. Manning studies how prolonged low oxygen levels and aging can alter the blood vessels of the lungs and affect heart function. His work aims to develop strategies that support long-term cardiopulmonary health.
Dr. Manning pursued his medical training at Albert Einstein College of Medicine, completed a residency at the Hospital of the University of Pennsylvania, and gained further expertise through a fellowship in pulmonary and critical care medicine at Yale School of Medicine.
Titles
- Assistant Professor of Medicine (Pulmonary)
Education & Training
- Pulmonary, Critical Care FellowshipYale School of Medicine (2020)
- ResidencyHospital of the University of Pennsylvania (2016)
- MDAlbert Einstein College of Medicine of Yeshiva University (2014)
- PhDAlbert Einstein College of Medicine of Yeshiva University, Biophysics (2014)
- MAHunter College - City University of New York, Physics (2005)
- MPATroy State University, Public Policy (2000)
- BSUniversity of Albany - State University of New York, Physics/Russian (1994)
Additional Information
Honors & Recognitions
- Butler-Williams Scholar: National Institute on Aging (2021)
- Pepper Scholar: Yale Pepper Center (2021)
- Young Physician Leadership Conference: Connecticut State Medical Society (2021)
- Fellow of the Year: Internal Medicine Residency Program, Yale School of Medicine (2017)
- Ger Award in Anatomy: Albert Einstein College of Medicine (2014)
- Dean's Recognition: Albert Einstein College of Medicine (2014)
Board Certifications
- National Board of Echocardiography, Adult Echocardiography (2021)
Professional Service
- Clinician-Scientists Transdisciplinary Aging Research Coordinating Center (2022 - 2023): Committee Member
- AMSUS The Society for Federal Health Professionals (2013 - 2020): Reviewer
Publications
- Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, Murphy T, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey J. Stiffening of the human proximal pulmonary artery with increasing age. Physiological Reports 2024, 12: e16090. PMID: 38884325, PMCID: PMC11181131, DOI: 10.14814/phy2.16090.
- Harris Z, Sun Y, Korde A, Hu B, Sharma L, Manning E, Joerns J, Clark B, Stanley G, Shin H, Placek L, Unutmaz D, Chun H, Sauler M, Rajagopalan G, Zhang X, Wang H, Kang M, Koff J. Epidermal Growth Factor Receptor Regulates Beclin-1 in Hyperoxia-Induced Lung Injury. 2024, a6841-a6841. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6841.
- Khoury J, Ahangari F, Manning E, Justet A, barnthaler T, Adams T, Necola F, Alysandratos K, Beermann M, Kotton D, Kaminski N. Profibrotic Role of GPR87 in Pulmonary Fibrosis. 2024, a5183-a5183. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5183.
- Ramachandra A, Jiang B, Jennings I, Manning E, Humphrey J. Remodeling of Murine Branch Pulmonary Arteries Under Chronic Hypoxia and Short-Term Normoxic Recovery. Journal Of Biomechanical Engineering 2024, 146 PMID: 38421341, DOI: 10.1115/1.4064967.
- Weil K, Baumann V, Brown B, Nadeau R, Hrdlicka H, Gerstenhaber B, Rosenblum D, Manning E. Guillain-Barre in the long-term acute care hospital setting: Ventilation does not prolong stay. Journal Of Mechanical Ventilation 2024, 5: 13-19. DOI: 10.53097/jmv.10094.
- Bärnthaler T, Ramachandra A, Ebanks S, Guerrera N, Sharma L, Dela Cruz C, Humphrey J, Manning E. Developmental changes in lung function of mice are independent of sex as a biological variable. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2024, 326: l627-l637. PMID: 38375577, PMCID: PMC11380952, DOI: 10.1152/ajplung.00120.2023.
- Schupp J, Manning E, Chioccioli M, Kamp J, Christian L, Ryu C, Herzog E, Kühnel M, Prasse A, Kaminski N, Jonigk D, Homer R, Neubert L, Ius F, stringJustet A, Hariri L, Seeliger B, Welte T, Knipe R, Gottlieb J. Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 819-822. PMID: 37552025, PMCID: PMC10563189, DOI: 10.1164/rccm.202303-0544le.
- Kim S, Adams T, Hu Q, Shin H, Chae G, Lee S, Sharma L, Kwon H, Lee F, Park H, Huh W, Manning E, Kaminski N, Sauler M, Chen L, Song J, Kim T, Kang M. VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis. American Journal Of Respiratory Cell And Molecular Biology 2023, 69: 22-33. PMID: 36450109, PMCID: PMC10324045, DOI: 10.1165/rcmb.2022-0219oc.
- Yuan Y, Khoury J, Ramachandra A, Singh I, Tellides G, Humphrey J, Kaminski N, Manning E. The Extracellular Matrix of the Human Proximal Pulmonary Artery Regulates Gene Expression of Resident Cells Responsible for Remodeling During Aging. 2023, a2680-a2680. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2680.
- Manning E, Ramachandra A, Cavinato C, Schupp J, Justet A, Lee P, Heerdt P, Singh I, Murphy T, Gill T, Tellides G, Kaminski N, Humphrey J. Age-related Changes in Structure, Function, and Transcriptomics of the Human Proximal Pulmonary Artery. 2023, a4656-a4656. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4656.
- Manning E, Ramachandra A, Cavinato C, Lee P, Heerdt P, Singh I, Tellides G, Kaminski N, Humphrey J. Pulmonary Hypertension-related Changes in Structure and Function of the Human Proximal Pulmonary Artery. 2023, a6133-a6133. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6133.
- Weil K, Baumann V, Brown B, Jano L, Nadeau R, Rosenblum D, Gerstenhaber B, Manning E. Patients With Acute Guillain-Barre Syndrome in Long-Term Acute Care. 2023, a3926-a3926. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3926.
- Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E. Prognostic variables and decannulation of tracheostomy in the long-term acute care environment: a case for clinician-driven decision-making. Journal Of Mechanical Ventilation 2023, 4: 1-8. PMID: 37426175, PMCID: PMC10328447, DOI: 10.53097/jmv.10069.
- Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E. The association between beta-natriuretic peptide (BNP) serum levels and liberation from mechanical ventilation. Pulmonary Medicine & Respiratory Research 2023, 9: 1-3. PMID: 38188724, PMCID: PMC10768849, DOI: 10.24966/pmrr-0177/100075.
- Harris ZM, Sun Y, Joerns J, Clark B, Hu B, Korde A, Sharma L, Shin HJ, Manning EP, Placek L, Unutmaz D, Stanley G, Chun H, Sauler M, Rajagopalan G, Zhang X, Kang MJ, Koff JL. Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia‐Induced Lung Injury. Oxidative Medicine And Cellular Longevity 2022, 2022: 9518592. PMID: 36193076, PMCID: PMC9526641, DOI: 10.1155/2022/9518592.
- Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E. Prognostic Variables and Decannulation of Tracheostomy in the Long-Term Acute Care Hospital Environment: A Case for Clinician-Driven Decision-Making. 2022, a4305-a4305. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4305.
- Ramachandra AB, Mikush N, Sauler M, Humphrey JD, Manning EP. Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice. Journal Of Biomechanical Engineering 2022, 144 PMID: 35171214, PMCID: PMC8990734, DOI: 10.1115/1.4053873.
- Manning EP, Ramachandra AB, Schupp JC, Cavinato C, Raredon MSB, Bärnthaler T, Cosme C, Singh I, Tellides G, Kaminski N, Humphrey JD. Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data. Frontiers In Physiology 2021, 12: 726253. PMID: 34594238, PMCID: PMC8478173, DOI: 10.3389/fphys.2021.726253.
- Schupp JC, Adams TS, Cosme C, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe’er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. Circulation 2021, 144: 286-302. PMID: 34030460, PMCID: PMC8300155, DOI: 10.1161/circulationaha.120.052318.
- Manning EP, Stephens MD, Dufresne S, Silver B, Gerbarg P, Gerbarg Z, Dela Cruz CS, Sharma L. Disinfection of Pseudomonas aeruginosa from N95 respirators with ozone: a pilot study. BMJ Open Respiratory Research 2021, 8: e000781. PMID: 33431507, PMCID: PMC7802653, DOI: 10.1136/bmjresp-2020-000781.
- Centor RM, Manning EP. Web Exclusive. Annals On Call - Are VA Patients Different? Annals Of Internal Medicine 2020, 172: oc1. PMID: 32066167, DOI: 10.7326/a19-0024.
- Manning EP. A Veteran-Centric Model of Care: Crossing the Cultural Divide. Annals Of Internal Medicine 2019, 171: 843-844. PMID: 31658471, PMCID: PMC7188555, DOI: 10.7326/m19-1264.
- Ryu C, Brandsdorfer C, Adams T, Hu B, Kelleher DW, Yaggi M, Manning EP, Walia A, Reeves B, Pan H, Winkler J, Minasyan M, Dela Cruz CS, Kaminski N, Gulati M, Herzog EL. Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis. European Respiratory Journal 2019, 54: 1801762. PMID: 31273041, PMCID: PMC8088542, DOI: 10.1183/13993003.01762-2018.
- Manning EP, Losier A, Emeagwali N, Ryu C, Honiden S. New Applications of Old Drugs as Novel Therapies in Idiopathic Pulmonary Fibrosis. Metformin, Hydroxychloroquine, and Thyroid Hormone. American Journal Of Respiratory And Critical Care Medicine 2019, 199: 1561-1563. PMID: 30822095, PMCID: PMC7051474, DOI: 10.1164/rccm.201809-1700rr.
- Hakim A, Bazan IS, Sanogo ML, Manning EP, Pollak JS, Chupp GL. Pulmonary artery pseudoaneurysm causing massive hemoptysis in hyperimmunoglobulin E syndrome: a case report. BMC Pulmonary Medicine 2019, 19: 34. PMID: 30736787, PMCID: PMC6368789, DOI: 10.1186/s12890-019-0797-7.
- Manning EP, Mishall PL, Weidmann MD, Flax H, Lan S, Erlich M, Burton WB, Olson TR, Downie SA. Early and prolonged opportunities to practice suturing increases medical student comfort with suturing during clerkships: Suturing during cadaver dissection. Anatomical Sciences Education 2018, 11: 605-612. PMID: 29603672, PMCID: PMC6165707, DOI: 10.1002/ase.1785.
- Is Repeating Direct-Fluorescent Antibody Testing for Influenza Beneficial?Manning EP, Moskowitz CS. Connecticut Medicine 2018; 82:487-488.
- Manning EP. Central Nervous System Oxygen Toxicity and Hyperbaric Oxygen Seizures. Aerospace Medicine And Human Performance 2016, 87: 477-486. PMID: 27099087, PMCID: PMC7092644, DOI: 10.3357/amhp.4463.2016.
- Manning EP, Vattipallly V, Niazi M, Shah A. PhytobezoarInduced Small Bowel Obstruction in a Young Male with Virgin Abdomen. Journal Of Gastrointestinal & Digestive System 2015, 05: 266. PMID: 29795770, PMCID: PMC5962263, DOI: 10.4172/2161-069x.1000266.
- Manning EP, Laskowski LK, Nelson LS, Touger M. Young Woman With Epigastric Pain and Vomiting. Annals Of Emergency Medicine 2014, 64: 330-333. PMID: 25149968, PMCID: PMC4203436, DOI: 10.1016/j.annemergmed.2013.12.022.
- Manning E, Lehman S, Schwartz S, Tardiff J. Computational Prediction and Experimental Verification of Differential Calcium Affinity in Thin Filament Mutants Known to Cause Hypertrophic Cardiomyopathy. Biophysical Journal 2014, 106: 349a. DOI: 10.1016/j.bpj.2013.11.1985.
- Manning EP, Tardiff JC, Schwartz SD. Molecular Effects of Familial Hypertrophic Cardiomyopathy-Related Mutations in the TNT1 Domain of cTnT. Journal Of Molecular Biology 2012, 421: 54-66. PMID: 22579624, PMCID: PMC3545441, DOI: 10.1016/j.jmb.2012.05.008.
- Manning EP, Guinto PJ, Tardiff JC. Correlation of Molecular and Functional Effects of Mutations in Cardiac Troponin T Linked to Familial Hypertrophic Cardiomyopathy. Journal Of Biological Chemistry 2012, 287: 14515-14523. PMID: 22334656, PMCID: PMC3340284, DOI: 10.1074/jbc.m111.257436.
- Manning EP, Tardiff JC, Schwartz SD. A Model of Calcium Activation of the Cardiac Thin Filament. Biochemistry 2011, 50: 7405-7413. PMID: 21797264, PMCID: PMC3165030, DOI: 10.1021/bi200506k.
- Manning E, Tardiff J, Schwartz S. Computational Modeling of Cardiac Troponin Dynamics: Elucidating a Regulatory Mechanism for Calcium Activation of the Thin Filament. Biophysical Journal 2011, 100: 225a. DOI: 10.1016/j.bpj.2010.12.1440.
- Guinto P, Manning E, Moore R, Schwartz S, Tardiff J. Structural and Functional Characterization of Cardiac Troponin T Mutations in the TNT1 Domain That Cause Familial Hypertrophic Cardiomyopathy. Biophysical Journal 2009, 96: 499a. DOI: 10.1016/j.bpj.2008.12.2575.
- Guinto PJ, Manning EP, Schwartz SD, Tardiff JC. COMPUTATIONAL CHARACTERIZATION OF MUTATIONS IN CARDIAC TROPONIN T KNOWN TO CAUSE FAMILIAL HYPERTROPHIC CARDIOMYOPATHY. Journal Of Computational Biophysics And Chemistry 2007, 6: 413-419. PMID: 26500385, PMCID: PMC4617307, DOI: 10.1142/s0219633607003271.
- Manning EP, Wilson B. Dehydration in extreme temperatures while conducting stability and support operations in a combat zone. Military Medicine 2007, 172: 972-6. PMID: 17937362, DOI: 10.7205/milmed.172.9.972.
- Nuraje N, Su K, Haboosheh A, Samson J, Manning EP, Yang NL, Matsui H. Room Temperature Synthesis of Ferroelectric Barium Titanate Nanoparticles Using Peptide Nanorings as Templates. Advanced Materials (Deerfield Beach, Fla.) 2006, 18: 807-811. PMID: 31031545, PMCID: PMC6482853, DOI: 10.1002/adma.200501340.
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