Basmah Safdar, MD, FACEP

Shimokawa H, Suda A, Takahashi J, Berry C, Camici PG, Crea F, Escaned J, Ford T, Yii E, Kaski JC, Kiyooka T, Mehta PK, Ong P, Ozaki Y, Pepine C, Rimoldi O, Safdar B, Sechtem U, Tsujita K, Yasuda S, Beltrame JF, Merz CNB, Group O. Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group. European Heart Journal 2021, 42: 4592-4600. PMID: 34038937, PMCID: PMC8633728, DOI: 10.1093/eurheartj/ehab282.

Madsen TE, Heron S, Lall MD, Blomkalns A, Arbelaez C, Lopez B, Lin M, Rounds K, Sethuraman KN, Safdar B. Institutional solutions addressing disparities in compensation and advancement of emergency medicine physicians: A critical appraisal of gaps and associated recommendations. Academic Emergency Medicine 2022, 29: 710-718. PMID: 35064998, DOI: 10.1111/acem.14452.

Solnick RE, Peyton K, Kraft-Todd G, Safdar B. Effect of Physician Gender and Race on Simulated Patients’ Ratings and Confidence in Their Physicians. JAMA Network Open 2020, 3: e1920511. PMID: 32083686, PMCID: PMC7043197, DOI: 10.1001/jamanetworkopen.2019.20511.

Safdar B, Mangi AA. Survival of the Fittest: Impact of Cardiorespiratory Fitness on Outcomes in Men and Women with Cardiovascular Disease. Clinical Therapeutics 2020, 42: 385-392. PMID: 32088022, DOI: 10.1016/j.clinthera.2020.01.014.

Safdar B. Chapter 6 Cardiovascular disease: Sex and gender evidence in acute ischemic syndrome and heart failure. 2021, 101-127. DOI: 10.1016/b978-0-12-816569-0.00006-1.

Safdar B, Sobiesk M, Bertsimas D, Nowroozpoor A, Deng Y, D’Onofrio G, Dziura J, El-Khoury J, Guo X, Simonov M, Taylor R, Wang M, Desir G. Renalase Identified by Machine Learning Methods as A Novel Independent Predictor of Mortality in Hospitalized Patients with COVID-19. Journal Of Biotechnology And Biomedicine 2024, 07 DOI: 10.26502/jbb.2642-91280139.

Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. Association of renalase with clinical outcomes in hospitalized patients with COVID-19. PLOS ONE 2022, 17: e0264178. PMID: 35259186, PMCID: PMC8903289, DOI: 10.1371/journal.pone.0264178.

Nowroozpoor A, Gutterman D, Safdar B. Is microvascular dysfunction a systemic disorder with common biomarkers found in the heart, brain, and kidneys? — A scoping review. Microvascular Research 2020, 134: 104123. PMID: 33333140, DOI: 10.1016/j.mvr.2020.104123.

Ong P, Safdar B, Seitz A, Hubert A, Beltrame J, Prescott E. Diagnosis of coronary microvascular dysfunction in the clinic. Cardiovascular Research 2020, 116: 841-855. PMID: 31904824, DOI: 10.1093/cvr/cvz339.

Safdar B, Guo X, Johnson C, D'Onofrio G, Dziura J, Sinusas AJ, Testani J, Rao V, Desir G. Elevated renalase levels in patients with acute coronary microvascular dysfunction – A possible biomarker for ischemia. International Journal Of Cardiology 2019, 279: 155-161. PMID: 30630613, PMCID: PMC6482834, DOI: 10.1016/j.ijcard.2018.12.061.

Safdar B. Clues to Diagnose Myocardial Infarction in the Young No Longer a Needle in the Haystack ∗. Journal Of The American College Of Cardiology 2019, 73: 585-588. PMID: 30732712, DOI: 10.1016/j.jacc.2018.11.034.

Madsen TE, Heron SL, Rounds K, Kass D, Lall M, Sethuraman KN, Arbelaez C, Blomkalns A, Safdar B, Taskforce T. Making Promotion Count: The Gender Perspective. Academic Emergency Medicine 2019, 26: 335-338. PMID: 30628138, DOI: 10.1111/acem.13680.

Madsen TE, Linden JA, Rounds K, Hsieh Y, Lopez BL, Boatright D, Garg N, Heron SL, Jameson A, Kass D, Lall MD, Melendez AM, Scheulen JJ, Sethuraman KN, Westafer LM, Safdar B. Current Status of Gender and Racial/Ethnic Disparities Among Academic Emergency Medicine Physicians. Academic Emergency Medicine 2017, 24: 1182-1192. PMID: 28779488, DOI: 10.1111/acem.13269.

Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D'Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction. Circulation 2018, 137: 781-790. PMID: 29459463, PMCID: PMC5822747, DOI: 10.1161/circulationaha.117.031650.

Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency department. European Heart Journal Acute Cardiovascular Care 2018, 9: 5-13. PMID: 29543037, DOI: 10.1177/2048872618764418.

Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.

Safdar B, Ong P, Camici PG. Identifying Myocardial Ischemia due to Coronary Microvascular Dysfunction in the Emergency Department: Introducing a New Paradigm in Acute Chest Pain Evaluation. Clinical Therapeutics 2018, 40: 1920-1930. PMID: 30458932, DOI: 10.1016/j.clinthera.2018.09.010.

DeCuir J, Surie D, Zhu Y, Lauring A, Gaglani M, McNeal T, Ghamande S, Peltan I, Brown S, Ginde A, Steinwand A, Mohr N, Gibbs K, Hager D, Ali H, Frosch A, Gong M, Mohamed A, Johnson N, Srinivasan V, Steingrub J, Khan A, Busse L, Duggal A, Wilson J, Qadir N, Chang S, Mallow C, Kwon J, Exline M, Shapiro N, Columbus C, Vaughn I, Ramesh M, Safdar B, Mosier J, Casey J, Talbot H, Rice T, Halasa N, Chappell J, Grijalva C, Baughman A, Womack K, Rhoads J, Swan S, Johnson C, Lewis N, Ellington S, Dawood F, McMorrow M, Self W, Network F. Effectiveness of Original Monovalent and Bivalent COVID‐19 Vaccines Against COVID‐19‐Associated Hospitalization and Severe In‐Hospital Outcomes Among Adults in the United States, September 2022–August 2023. Influenza And Other Respiratory Viruses 2024, 18: e70027. PMID: 39496339, PMCID: PMC11534416, DOI: 10.1111/irv.70027.

Liu Y, Wang Z, Collins S, Testani J, Kleinstein S, Safdar B. Sex differences in proteomics of cardiovascular disease: results from the Yale-CMD registry. European Heart Journal 2024, 45: ehae666.3091. DOI: 10.1093/eurheartj/ehae666.3091.

Oh M, Currier J, Khan A, Mylonakis E, Newell M, Ignacio R, Jilg N, Safdar B, Merck L, Smith D. Lessons learned from COVID-19 to overcome challenges in conducting outpatient clinical trials to find safe and effective therapeutics for the next infectious pandemic. Journal Of Clinical And Translational Science 2024, 8: e153. DOI: 10.1017/cts.2024.607.

Surie D, Self W, Zhu Y, Yuengling K, Johnson C, Grijalva C, Dawood F, Gaglani M, Ghamande S, McNeal T, Columbus C, Gottlieb R, Steingrub J, DeCuir J, McMorrow M, Ellington S, Lewis N, Duggal A, Busse L, Bender W, Prekker M, Frosch A, Peltan I, Brown S, Hager D, Gong M, Mohamed A, Khan A, Hough C, Wilson J, Mosier J, Qadir N, Chang S, Ginde A, Mohr N, Zepeski A, Mallow C, Lauring A, Martin E, Leis A, Harris E, Johnson N, Srinivasan V, Talbot H, Halasa N, Chappell J, Womack K, Rhoads J, Baughman A, Swan S, Rice T, Casey J, Blair P, Gibbs K, Kwon J, Parikh B, Vaughn I, Ramesh M, Safdar B. RSV Vaccine Effectiveness Against Hospitalization Among US Adults 60 Years and Older. JAMA 2024, 332: 1105-1107. PMID: 39230920, PMCID: PMC11375516, DOI: 10.1001/jama.2024.15775.

Wright D, Zhou B, Wright C, Axtell R, Mangi A, Safdar B. Association Between Exercise Program Participation and Hospitalization of Older Adults. American Journal Of Preventive Medicine 2024 PMID: 39218409, DOI: 10.1016/j.amepre.2024.08.017.

C K, Surie D, Lauring A, Martin E, Leis A, Papalambros L, Gaglani M, Columbus C, Gottlieb R, Ghamande S, Peltan I, Brown S, Ginde A, Mohr N, Gibbs K, Hager D, Saeed S, Prekker M, Gong M, Mohamed A, Johnson N, Srinivasan V, Steingrub J, Khan A, Hough C, Duggal A, Wilson J, Qadir N, Chang S, Mallow C, Kwon J, Parikh B, Exline M, Vaughn I, Ramesh M, Safdar B, Mosier J, Harris E, Shapiro N, Felzer J, Zhu Y, Grijalva C, Halasa N, Chappell J, Womack K, Rhoads J, Baughman A, Swan S, Johnson C, Rice T, Casey J, Blair P, Han J, Ellington S, Lewis N, Thornburg N, Paden C, Atherton L, Self W, Dawood F, DeCuir J. Effectiveness of Updated 2023–2024 (Monovalent XBB.1.5) COVID-19 Vaccination Against SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 Lineage Hospitalization and a Comparison of Clinical Severity—IVY Network, 26 Hospitals, 18 October 2023–9 March 2024. Clinical Infectious Diseases 2024, ciae405. PMID: 39107255, DOI: 10.1093/cid/ciae405.

Surie D, Yuengling K, DeCuir J, Zhu Y, Lauring A, Gaglani M, Ghamande S, Peltan I, Brown S, Ginde A, Martinez A, Mohr N, Gibbs K, Hager D, Ali H, Prekker M, Gong M, Mohamed A, Johnson N, Srinivasan V, Steingrub J, Leis A, Khan A, Hough C, Bender W, Duggal A, Bendall E, Wilson J, Qadir N, Chang S, Mallow C, Kwon J, Exline M, Shapiro N, Columbus C, Vaughn I, Ramesh M, Mosier J, Safdar B, Casey J, Talbot H, Rice T, Halasa N, Chappell J, Grijalva C, Baughman A, Womack K, Swan S, Johnson C, Lwin C, Lewis N, Ellington S, McMorrow M, Martin E, Self W. Severity of Respiratory Syncytial Virus vs COVID-19 and Influenza Among Hospitalized US Adults. JAMA Network Open 2024, 7: e244954. PMID: 38573635, PMCID: PMC11192181, DOI: 10.1001/jamanetworkopen.2024.4954.

Frutos A, Price A, Harker E, Reeves E, Ahmad H, Murugan V, Martin E, House S, Saade E, Zimmerman R, Gaglani M, Wernli K, Walter E, Michaels M, Staat M, Weinberg G, Selvarangan R, Boom J, Klein E, Halasa N, Ginde A, Gibbs K, Zhu Y, Self W, Tartof S, Klein N, Dascomb K, DeSilva M, Weber Z, Yang D, Ball S, Surie D, DeCuir J, Dawood F, Moline H, Toepfer A, Clopper B, Link-Gelles R, Payne A, Chung J, Flannery B, Lewis N, Olson S, Adams K, Tenforde M, Garg S, Grohskopf L, Reed C, Ellington S, Collaborators C, Collaborators C, Lauring A, Arndorfer J, Bride D, Peltan I, Mohr N, Hager D, Prekker M, Mohamed A, Johnson N, Steingrub J, Khan A, Busse L, Duggal A, Wilson J, Qadir N, Mallow C, Kwon J, Exline M, Shapiro N, Columbus C, Vaughan I, Mosier J, Safdar B, Harris E, Chappell J, Stewart L, Swan S, Piedra P, Sahni L, Englund J, Zerr D, Hickey R, Williams J, Rohlfs C, Schlaudecker E, Dosdos D, Moffatt M, Schuster J, Weltmer K, Szilagyi P, Curley T, Mills J, Faryar K, Salata R, Geffel K, Nowalk M, Murthy K, Rose S, Smith M, Wickersham B, Williamson B, Bontrager N, Williams O, Kramer J, Nordstrom L, Monto A, Vaughn I, Dickerson M, McLean C, Noble E, Ray C, Sumner K, Essien I, Fletcher L, Heaton P, Kane S, McEvoy C, Thapa S, Vazquez-Benitez G, Bezi C, Contreras R, Davis G, Lewin B, Mahale P, Patrick R, Qian L, Rayens E, Reyes I, Ryan D, Salas S, Sy L, Yeh M, Zeng X, Fireman B, Goddard K, Hansen J, Jacobson K, Timbol J, Zerbo O, Dunne M, Zhuang Y. Interim Estimates of 2023–24 Seasonal Influenza Vaccine Effectiveness — United States. MMWR Morbidity And Mortality Weekly Report 2024, 73: 168-174. PMID: 38421935, PMCID: PMC10907036, DOI: 10.15585/mmwr.mm7308a3.

DeCuir J, Payne A, Self W, Rowley E, Dascomb K, DeSilva M, Irving S, Grannis S, Ong T, Klein N, Weber Z, Reese S, Ball S, Barron M, Naleway A, Dixon B, Essien I, Bride D, Natarajan K, Fireman B, Shah A, Okwuazi E, Wiegand R, Zhu Y, Lauring A, Martin E, Gaglani M, Peltan I, Brown S, Ginde A, Mohr N, Gibbs K, Hager D, Prekker M, Mohamed A, Srinivasan V, Steingrub J, Khan A, Busse L, Duggal A, Wilson J, Chang S, Mallow C, Kwon J, Exline M, Columbus C, Vaughn I, Safdar B, Mosier J, Harris E, Casey J, Chappell J, Grijalva C, Swan S, Johnson C, Lewis N, Ellington S, Adams K, Tenforde M, Paden C, Dawood F, Fleming-Dutra K, Surie D, Link-Gelles R, Collaborators C, Collaborators C, Ghamande S, Gottlieb R, McNeal T, Raver C, Bender W, Fletcher L, Heaton P, Kane S, McEvoy C, Thapa S, Vazquez-Benitez G, Frosch A, Lamerato L, Ramesh M, Arnofer J, Ali H, Hopkins J, Crane B, Dandamudi P, Goddard K, Hansen J, Timbol J, Zerbo O, Allen K, Duszynski T, Fadel W, Rogerson C, Qadir N, Chavez C, Doyle B, Mayer D, Rao S, Rivas C, Johnson N, Baughman A, Lwin C, Rhoads J, Womack K, Dunne M, Ciesla A, Mak J, Najdowski M, Ray C. Interim Effectiveness of Updated 2023–2024 (Monovalent XBB.1.5) COVID-19 Vaccines Against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalization Among Immunocompetent Adults Aged ≥18 Years — VISION and IVY Networks, September 2023–January 2024. MMWR Morbidity And Mortality Weekly Report 2024, 73: 180-188. PMID: 38421945, PMCID: PMC10907041, DOI: 10.15585/mmwr.mm7308a5.

Lewis N, Zhu Y, Peltan I, Gaglani M, McNeal T, Ghamande S, Steingrub J, Shapiro N, Duggal A, Bender W, Taghizadeh L, Brown S, Hager D, Gong M, Mohamed A, Exline M, Khan A, Wilson J, Qadir N, Chang S, Ginde A, Mohr N, Mallow C, Lauring A, Johnson N, Gibbs K, Kwon J, Columbus C, Gottlieb R, Raver C, Vaughn I, Ramesh M, Johnson C, Lamerato L, Safdar B, Casey J, Rice T, Halasa N, Chappell J, Grijalva C, Talbot H, Baughman A, Womack K, Swan S, Harker E, Price A, DeCuir J, Surie D, Ellington S, Self W, Calhoun N, Murthy K, Cravens J, Herrick J, McKillop A, Hoffman E, Graves A, Zayed M, Smith M, Scott B, Health W, Fisher T, Hurutado-Rodriguez M, Kruse T, Dunkley S, Perez G, Bychkowski A, Grefsrud T, Calhoun N, Murthy K, Herrick J, Smith M, Steingrub J, Kozikowski L, De Souza L, Ouellette S, Shapiro N, Bolstad M, Coviello B, Ciottone R, Devilla A, Grafals A, Higgins C, Ottanelli C, Redman K, Scaffidi D, Weingart A, Surie D, McMorrow M, DeCuir J, Lewis N, Harker E, Ellington S, Mehkri O, Mitchell M, Griffith Z, Brennan C, Ashok K, Poynter B, Duggal A, Busse L, Lohuis C, Stanley N, Zhang S, Prekker M, Frosch A, Hendrickson A, Douglas S, Hurreh K, Peltan I, Smith C, Marshall H, Hager D, Ali H, Phan M, Gong M, Mohamed A, Nair R, Chen J, Exline M, Karow S, Khan M, So M, Snyder C, Swoope G, Smith D, Lee B, Rasul A, Pathak M, Lewald Z, Wilson R, Khan A, Peña J, Briceno G, Ahmed C, Martinez J, Pocius E, Oh M, Hyde J, Gause S, Wilson J, Gordon A, Perez C, Lau L, Bekiroglu I, Tran C, Frankel T, Garner O, Chandrasekaran S, Ginde A, Douin D, Martinez A, Huynh D, Steinwand A, Sullivan A, Withers C, Mohr N, Zepeski A, Nassar P, Landers S, Nielsen K, Briggs N, Fairfield C, Peebles A, Mallow C, Rivas C, Martin E, Monto A, Lauring A, McSpadden E, Truscon R, Kaniclides A, Thomas L, Bielak R, Valvano W, Fong R, Fitzsimmons W, Blair C, Gilbert J, Papalambros L, Holz A, Johnson N, Srinivasan V, Crider C, Steinbock K, Paulsen T, Anderson L, Self W, Talbot H, Grijalva C, Jones I, Halasa N, Chappell J, Womack K, Rhoads J, Baughman A, Kampe C, Johnson J, Swan S, Johnson C, Zhu Y, Rice T, Casey J, Stubblefield W, Zhu Y, Short L, Ezzell L, Whitsett M, McHenry R, Hargrave S, Blair M, Luther J, Pulido C, Peterson B, Files D, Gibbs K, Landreth L, Hicks M, Parks L, Kwon J, Parikh B, McDonald D, Samuels C, Vogt L, O’Neil C, Valencia A, Hink T, Bychkowski A, Dunkley S, Fisher T, Grefsrud T, Hurutado-Rodriguez M, Perez G, Beney K, Jayaprakash R, Koneru S, Lava J, Pinderi Z, Resk M, Goyal A, DeLamielleure L, Kosover M, Brokowski C. Vaccine Effectiveness Against Influenza A–Associated Hospitalization, Organ Failure, and Death: United States, 2022–2023. Clinical Infectious Diseases 2023, 78: 1056-1064. PMID: 38051664, PMCID: PMC11487098, DOI: 10.1093/cid/ciad677.

Yuengling K, Surie D, DeCuir J, Zhu Y, Gaglani M, Ginde A, Gibbs K, Prekker M, Mohamed A, Johnson N, Peltan I, Bender W, Mallow C, Kwon J, Lauring A, Columbus C, Vaughn I, Safdar B, Chappell J, Baughman A, Swan S, Johnson C, McMorrow M, Self W, Martin E. 1108. Severity of Illness among Adults Hospitalized with Respiratory Syncytial Virus Compared with COVID-19 and Influenza — IVY Network, 25 Hospitals, 20 U.S. States, January 31, 2022 – April 11, 2023. Open Forum Infectious Diseases 2023, 10: ofad500.081. PMCID: PMC10678102, DOI: 10.1093/ofid/ofad500.081.

DeCuir J, Zhu Y, Gaglani M, Ginde A, Mohr N, Gibbs K, Hager D, Frosch A, Mohamed A, Johnson N, Steingrub J, Peltan I, Martin E, Bender W, Wilson J, Qadir N, Mallow C, Kwon J, Exline M, Lauring A, Columbus C, Vaughn I, Safdar B, Chappell J, Baughman A, Womack K, Swan S, McMorrow M, Self W, Surie D. 2083. Waning of Bivalent mRNA Vaccine Effectiveness Against COVID-19-associated Hospitalization Among Immunocompetent Adults Aged ≥65 Years – IVY Network, 20 U.S. States, September 8, 2022-April 1, 2023. Open Forum Infectious Diseases 2023, 10: ofad500.153. PMCID: PMC10677158, DOI: 10.1093/ofid/ofad500.153.

Surie D, Yuengling K, DeCuir J, Zhu Y, Gaglani M, Ginde A, Talbot H, Casey J, Mohr N, Ghamande S, Gibbs K, Files D, Hager D, Ali H, Prekker M, Gong M, Mohamed A, Johnson N, Steingrub J, Peltan I, Brown S, Leis A, Khan A, Hough C, Bender W, Duggal A, Wilson J, Qadir N, Chang S, Mallow C, Kwon J, Exline M, Lauring A, Shapiro N, Columbus C, Vaughn I, Ramesh M, Safdar B, Halasa N, Chappell J, Grijalva C, Baughman A, Rice T, Womack K, Han J, Swan S, Mukherjee I, Lewis N, Ellington S, McMorrow M, Martin E, Self W, Network I. Disease Severity of Respiratory Syncytial Virus Compared with COVID-19 and Influenza Among Hospitalized Adults Aged ≥60 Years — IVY Network, 20 U.S. States, February 2022–May 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 1083-1088. PMID: 37796753, PMCID: PMC10564326, DOI: 10.15585/mmwr.mm7240a2.

Rafique Z, Safdar B, Duanmu Y, Boone S, Bishof J, Meltzer A, Budden J, Milliet C, Soto-Ruiz K, Peacock W. 55 Patiromer Utility as an Adjunct Treatment in Patients Needing Urgent Hyperkalemia Management (PLATINUM). Annals Of Emergency Medicine 2023, 82: s22-s23. DOI: 10.1016/j.annemergmed.2023.08.075.

Rafique Z, Budden J, Quinn C, Duanmu Y, Safdar B, Bischof J, Driver B, Herzog C, Weir M, Singer A, Boone S, Soto-Ruiz K, Peacock W. Patiromer utility as an adjunct treatment in patients needing urgent hyperkalaemia management (PLATINUM): design of a multicentre, randomised, double-blind, placebo-controlled, parallel-group study. BMJ Open 2023, 13: e071311. PMID: 37308268, PMCID: PMC10277034, DOI: 10.1136/bmjopen-2022-071311.

de Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.

Self W, Shotwell M, Gibbs K, de Wit M, Files D, Harkins M, Hudock K, Merck L, Moskowitz A, Apodaca K, Barksdale A, Safdar B, Javaheri A, Sturek J, Schrager H, Iovine N, Tiffany B, Douglas I, Levitt J, Busse L, Ginde A, Brown S, Hager D, Boyle K, Duggal A, Khan A, Lanspa M, Chen P, Puskarich M, Vonderhaar D, Venkateshaiah L, Gentile N, Rosenberg Y, Troendle J, Bistran-Hall A, DeClercq J, Lavieri R, Joly M, Orr M, Pulley J, Rice T, Schildcrout J, Semler M, Wang L, Bernard G, Collins S, Becker R, del Zoppo G, Henke P, Holubkov R, Johnson M, Kerr K, Lipman H, Lurie F, Pitt B, Vesely S, Fleg J, Aamodt D, Ayers J, Clark D, Collins J, Cook M, Dixon S, Graves J, Jordan C, Lindsell C, Lopez I, McKeel D, Orozco D, Prato N, Qi A, Qutab M, Stoughton C, Vermillion K, Walsh K, Winchell S, Young T, Franklin R, Wagner E, Walther T, Demitrack M, Johnson J, Walsh R, Bales B, Miller K, Torr D, Barot H, Landreth L, LaRose M, Parks L, Teixeira J, Cardenas S, Ceniceros J, Cunningham A, Kunkel S, Lovato D, Zimmerman B, Nguyen T, Zeger W, Nichols H, Wiedel N, Javaheri A, Stilinovic S, Brokowski C, Lu J, Solberg M, Lee D, Roach K, Tiffany B, Tanner C, Taylor A, Zumbahl J, Syed A, Mason J, Jackson P, Coleman R, Haughey H, Cherabuddi K, James N, Wakeman R, Duncan C, Montero C, Rogers A, Wilson J, Vojnik R, Perez C, Wyles D, Hiller T, Oakes J, Garcia A, Gong M, Mohamed A, Andrea L, Nair R, Nkemdirim W, Lopez B, Boujid S, Torres M, Garcia O, Martinez F, Baduashvili A, Bastman J, Chauhan L, Douin D, Finck L, Licursi A, ten Lohuis C, Zhang S, Bender W, Tovar S, Hayes S, Kurtzman N, Rosseto E, Scaffidi D, Shapiro N, Pak J, Allada G, Briceno G, Peña J, Oh M, Ali H, Beselman S, Eby Y, Klimov V, Hite R, Tanzeem H, Droege C, Winter J, Jackman S, Caudill A, Bayoumi E, Pascual E, Chen P, Mucha S, Thiruchelvam N, Siuba M, Mehkri O, Driver B, Hendrickson A, Kaus O, Ontiveros C, Riehm A, Laudun S, Hudock D, Ensley C, Shaner V, Gentile N, Isenberg D, Reimer H, Cincola P, Harris E, Callahan S, Yamane M, Barrios M, Desai N, Bharara A, Keller M, Majumder P, Dohe C, D’Armiento J, Goldklang M, Wagener G, Fonseca L, Valezquez-Sanchez I, Johnson N, Petersen E, Fuentes M, Newton M, Gundel S, Srinivasan V, Steel T, Robinson B. Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor–Biased Ligand in Adults With COVID-19. JAMA 2023, 329: 1170-1182. PMID: 37039791, PMCID: PMC10091180, DOI: 10.1001/jama.2023.3546.

Alexander B, South A, August P, Bertagnolli M, Ferranti E, Grobe J, Jones E, Loria A, Safdar B, Sequeira-Lopez M, Health O. Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association. Hypertension 2023, 80: e75-e89. PMID: 36951054, PMCID: PMC10242542, DOI: 10.1161/hyp.0000000000000227.

Kayani J, Reed J, Safdar B, Langhan M. Women in pediatric emergency medicine: Trends in gender from 2000 to 2020. Academic Emergency Medicine 2023, 30: 675-677. PMID: 36545838, DOI: 10.1111/acem.14644.

Jarman AF, Safdar B, Madsen TE, Kane BG, McGregor AJ. Incorporating sex- and gender-based medicine into journal club. European Journal Of Emergency Medicine 2022, 29: 393-394. PMID: 36222813, PMCID: PMC10008087, DOI: 10.1097/mej.0000000000000973.

Zeidan A, Salhi B, Backster A, Shelton E, Valente A, Safdar B, Wong A, Della Porta A, Lee S, Schneberk T, Wilson J, Westgard B, Samuels-Kalow M. A Structural Competency Framework for Emergency Medicine Research: Results from a Scoping Review and Consensus Conference. Western Journal Of Emergency Medicine 2022, 23: 650-659. PMID: 36205664, PMCID: PMC9541992, DOI: 10.5811/westjem.2022.6.56056.

Safdar B, Mori M, Nowroozpoor A, Geirsson A, D'Onofrio G, Mangi AA. Clinical Profile and Sex-Specific Recovery With Cardiac Rehabilitation After Coronary Artery Bypass Grafting Surgery. Clinical Therapeutics 2022, 44: 846-858. PMID: 35570056, DOI: 10.1016/j.clinthera.2022.04.002.

Banco D, Chang J, Talmor N, Wadhera P, Mukhopadhyay A, Lu X, Dong S, Lu Y, Betensky RA, Blecker S, Safdar B, Reynolds HR. Sex and Race Differences in the Evaluation and Treatment of Young Adults Presenting to the Emergency Department With Chest Pain. Journal Of The American Heart Association 2022, 11: e024199. PMID: 35506534, PMCID: PMC9238573, DOI: 10.1161/jaha.121.024199.

Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.

Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.

Safdar B. Influence of Sex and Gender on Lifestyle Interventions for Cardiovascular Disease. Clinical Therapeutics 2021, 44: 8-10. PMID: 34973826, DOI: 10.1016/j.clinthera.2021.12.004.

Nowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Corrigendum to: Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 43: 1776-1776. PMID: 34897369, DOI: 10.1093/eurheartj/ehab845.

Nowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 42: ehab724.2744. DOI: 10.1093/eurheartj/ehab724.2744.

Gaeta M, Nowroozpoor A, Dziura J, D'Onofrio G, Sinusas AJ, Safdar B. Use of peripheral arterial tonometry in detection of abnormal coronary flow reserve. Microvascular Research 2021, 138: 104223. PMID: 34256085, PMCID: PMC10227886, DOI: 10.1016/j.mvr.2021.104223.

Wolfe J, Safdar B, Madsen TE, Sethuraman KN, Becker B, Greenberg MR, McGregor AJ. Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2. Clinical Therapeutics 2021, 43: 557-571.e1. PMID: 33583576, PMCID: PMC7833665, DOI: 10.1016/j.clinthera.2021.01.015.

Pendyal A, Rothenberg C, Scofi JE, Krumholz HM, Safdar B, Dreyer RP, Venkatesh AK. National Trends in Emergency Department Care Processes for Acute Myocardial Infarction in the United States, 2005 to 2015. Journal Of The American Heart Association 2020, 9: e017208. PMID: 33047624, PMCID: PMC7763391, DOI: 10.1161/jaha.120.017208.

Suda A, Takahashi J, Beltrame JF, Berry C, Camici PG, Crea F, Escaned J, Ford T, Kaski J, Kiyooka T, Metha PK, Ong P, Ozaki Y, Pepine C, Rimoldi O, Safdar B, Sechtem U, Tsujita K, Yii E, Merz C, Shimokawa H, Group O. International prospective cohort study of microvascular angina – Rationale and design. IJC Heart & Vasculature 2020, 31: 100630. PMID: 32984497, PMCID: PMC7494778, DOI: 10.1016/j.ijcha.2020.100630.

Jelani Q, Mena‐Hurtado C, Burg M, Soufer R, Gosch K, Jones PG, Spertus JA, Safdar B, Smolderen KG. Relationship Between Depressive Symptoms and Health Status in Peripheral Artery Disease: Role of Sex Differences. Journal Of The American Heart Association 2020, 9: e014583. PMID: 32781883, PMCID: PMC7660812, DOI: 10.1161/jaha.119.014583.

Madsen T, Dobiesz V, Das D, Sethuraman K, Agrawal P, Zeidan A, Goldberg E, Safdar B, Lall M. Unique Risks and Solutions for Equitable Advancement during the Covid-19 Pandemic: Early Experience from Frontline Physicians in Academic Medicine. NEJM Catalyst 2020 PMCID: PMC7380702, DOI: 10.1056/cat.20.0268.

Mehta LS, Warnes CA, Bradley E, Burton T, Economy K, Mehran R, Safdar B, Sharma G, Wood M, Valente AM, Volgman A, Council O. Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association. Circulation 2020, 141: e884-e903. PMID: 32362133, DOI: 10.1161/cir.0000000000000772.

Nowroozpoor A, Gutterman D, Safdar B. Utility of discovery approach using proteomics to create a biomarker profile for coronary microvascular dysfunction. Microvascular Research 2020, 129: 103985. PMID: 32007502, PMCID: PMC10291513, DOI: 10.1016/j.mvr.2020.103985.

Fodeh S, Li T, Jarad H, Safdar B. Classification of Patients with Coronary Microvascular Dysfunction. IEEE/ACM Transactions On Computational Biology And Bioinformatics 2019, 17: 704-711. PMID: 31056516, DOI: 10.1109/tcbb.2019.2914442.

Safdar B, Ayala K, Ali SS, Seifer BJ, Hong M, Greenberg MR, Choo EK, McGregor AJ. Inclusion of Sex and Gender in Emergency Medicine Research—A 2018 Update. Academic Emergency Medicine 2019, 26: 293-302. PMID: 30637897, DOI: 10.1111/acem.13688.

Fodeh S, Li T, Jarad H, Safdar B. Identifying Patients with Coronary Microvascular Dysfunction using Machine Learning. 2018, 00: 715-721. DOI: 10.1109/icdmw.2018.00109.

Jacob D, McNamara R, Safdar B. DOES 3-HOUR POINT OF CARE TROPONIN I PREDICT 6-HOUR POINT OF CARE TROPONIN I FOR PATIENTS IN A CHEST PAIN UNIT. Journal Of The American College Of Cardiology 2017, 69: 71. DOI: 10.1016/s0735-1097(17)33460-5.

Sciria C, Dreyer R, Safdar B, D'Onofrio G, Krumholz H, Spatz E. MECHANISMS OF ACUTE MYOCARDIAL INFARCTION IN YOUNG WOMEN AND DISCHARGE MEDICATION PATTERNS. Journal Of The American College Of Cardiology 2017, 69: 195. DOI: 10.1016/s0735-1097(17)33584-2.

Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.

Hamedani A, Safdar B, Aaronson E, Lee TH. Patient Experience Must Move Beyond Bad Apples. Annals Of Internal Medicine 2016, 165: 869-870. PMID: 27750283, DOI: 10.7326/m16-1725.

Safdar B, D'Onofrio G. Women and Chest Pain: Recognizing the Different Faces of Angina in the Emergency Department. The Yale Journal Of Biology And Medicine 2016, 89: 227-38. PMID: 27354848, PMCID: PMC4918863.

Kim Y, Soffler M, Paradise S, Naftilan M, Jelani Q, Dziura J, Sinha R, Safdar B. DEPRESSION AND ANXIETY ARE ASSOCIATED WITH HIGH RATES OF RECURRENT CHEST PAIN. Journal Of The American College Of Cardiology 2016, 67: 581. DOI: 10.1016/s0735-1097(16)30582-4.

Safdar B, D’Onofrio G, Dziura J, Russell R, Naftilan M, Johnson C, Sinusas A. MICROVASCULAR ANGINA IN THE ABSENCE OF CORONARY ARTERY DISEASE IS COMMON IN UNDIFFERENTIATED CHEST PAIN PATIENTS IN THE EMERGENCY DEPARTMENT. Journal Of The American College Of Cardiology 2016, 67: 1824. DOI: 10.1016/s0735-1097(16)31825-3.

Soffler M, McGregor A, Safdar B. It’s not all Chest Pain: Sex and Gender in Acute Care Cardiology. 2016, 6-23. DOI: 10.1017/cbo9781107705944.004.

Safdar B, Ali A, D’Onofrio G, Katz SD. Microvascular Dysfunction as Opposed to Conduit Artery Disease Explains Sex-specific Chest Pain in Emergency Department Patients With Low to Moderate Cardiac Risk. Clinical Therapeutics 2016, 38: 240-255.e1. PMID: 26778090, DOI: 10.1016/j.clinthera.2015.12.010.

D'Onofrio G, Safdar B, Lichtman JH, Strait KM, Dreyer RP, Geda M, Spertus JA, Krumholz HM. Sex Differences in Reperfusion in Young Patients With ST-Segment–Elevation Myocardial Infarction. Circulation 2015, 131: 1324-1332. PMID: 25792558, PMCID: PMC4652789, DOI: 10.1161/circulationaha.114.012293.

Wigginton JG, Perman SM, Barr GC, McGregor AJ, Miller AC, Napoli A, Safdar B, Weaver KR, Deutsch S, Kayea T, Becker L. Sex‐ and Gender‐specific Research Priorities in Cardiovascular Resuscitation: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Resuscitation Research Workgroup. Academic Emergency Medicine 2014, 21: 1343-1349. PMID: 25491706, PMCID: PMC6406034, DOI: 10.1111/acem.12541.

Safdar B, Stolz U, Stiell IG, Cone DC, Bobrow BJ, deBoehr M, Dreyer J, Maloney J, Spaite DW. Differential Survival for Men and Women from Out‐of‐hospital Cardiac Arrest Varies by Age: Results from the OPALS Study. Academic Emergency Medicine 2014, 21: 1503-1511. PMID: 25491713, DOI: 10.1111/acem.12540.

Safdar B, Greenberg MR. Organization, Execution and Evaluation of the 2014 Academic Emergency Medicine Consensus Conference on Gender‐Specific Research in Emergency Care – An Executive Summary. Academic Emergency Medicine 2014, 21: 1307-1317. PMID: 25420469, PMCID: PMC4340245, DOI: 10.1111/acem.12530.

Safdar B, Greenberg MR, Anise A, Brown J, Conwit R, Filart R, Scott J, Choo EK. Funding Mechanisms for Gender‐specific Research: Proceedings from a Panel Discussion at the 2014 Academic Emergency Medicine Consensus Conference. Academic Emergency Medicine 2014, 21: 1329-1333. PMID: 25413301, PMCID: PMC4278745, DOI: 10.1111/acem.12522.

Safdar B, Nagurney JT, Anise A, DeVon HA, D'Onofrio G, Hess EP, Hollander JE, Legato MJ, McGregor AJ, Scott J, Tewelde S, Diercks DB. Gender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup. Academic Emergency Medicine 2014, 21: 1350-1360. PMID: 25413468, PMCID: PMC6402042, DOI: 10.1111/acem.12527.

Safdar B, Bezek SK, Sinusas AJ, Russell RR, Klein MR, Dziura JD, D’onofrio G. Elevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit Patients. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2014, 13: 14-19. PMID: 24526146, DOI: 10.1097/hpc.0000000000000001.

McGregor A, Davenport M, Miner J, Siegel T, Safdar B. Gender‐specific Emergency Care: Part One. Academic Emergency Medicine 2013, 20: 1181-1181. DOI: 10.1111/acem.12242.

McGregor A, Safdar B, Greenberg M, Choo E. Gender‐specific Emergency Medicine Research: Overview and Opportunities. Academic Emergency Medicine 2013, 20: 1180-1180. DOI: 10.1111/acem.12239.

Diercks DB, Mumma BE, Peacock W, Hollander JE, Safdar B, Mahler SA, Miller CD, Counselman FL, Birkhahn R, Schrock J, Singer AJ, Nagurney JT. Incremental Value of Objective Cardiac Testing in Addition to Physician Impression and Serial Contemporary Troponin Measurements in Women. Academic Emergency Medicine 2013, 20: 265-270. PMID: 23517258, PMCID: PMC3725334, DOI: 10.1111/acem.12092.

McGregor AJ, Greenberg M, Safdar B, Seigel T, Hendrickson R, Poznanski S, Davenport M, Miner J, Choo EK. Focusing a Gender Lens on Emergency Medicine Research: 2012 Update. Academic Emergency Medicine 2013, 20: 313-320. PMID: 23517266, DOI: 10.1111/acem.12085.

Safdar B, Lichtman JH, D'Onofrio G. Sex and the CT: An Evolving Story of the Heart. Academic Emergency Medicine 2012, 19: 197-200. PMID: 22320371, DOI: 10.1111/j.1553-2712.2011.01288.x.

Diercks DB, Peacock WF, Hollander JE, Singer AJ, Birkhahn R, Shapiro N, Glynn T, Nowack R, Safdar B, Miller CD, Lewandrowski E, Nagurney JT. Diagnostic accuracy of a point-of-care troponin I assay for acute myocardial infarction within 3 hours after presentation in early presenters to the emergency department with chest pain. American Heart Journal 2012, 163: 74-80.e4. PMID: 22172439, DOI: 10.1016/j.ahj.2011.09.028.

Peacock WF, Nagurney J, Birkhahn R, Singer A, Shapiro N, Hollander J, Glynn T, Nowak R, Safdar B, Miller C, Peberdy M, Counselman F, Chandra A, Kosowsky J, Neuenschwander J, Schrock J, Plantholt S, Lewandrowski E, Wong V, Kupfer K, Diercks D. Myeloperoxidase in the diagnosis of acute coronary syndromes: The importance of spectrum. American Heart Journal 2011, 162: 893-899. PMID: 22093206, DOI: 10.1016/j.ahj.2011.08.017.

Safdar B, McGregor AJ, McKee SA, Ali A, Radulescu R, Himelfarb NT, Klein MR, Mazure CM. Inclusion of Gender in Emergency Medicine Research. Academic Emergency Medicine 2011, 18: e1-e4. PMID: 21314767, DOI: 10.1111/j.1553-2712.2010.00978.x.

Safdar B, Foody JM, D'Onofrio G. Depression as Modifiable Coronary Risk Factor in the Emergency Department Chest Pain Observation Unit. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2010, 9: 82-87. PMID: 20520215, DOI: 10.1097/hpc.0b013e3181db06ef.

Heins A, Homel P, Safdar B, Todd K. Physician Race/Ethnicity Predicts Successful Emergency Department Analgesia. Journal Of Pain 2010, 11: 692-697. PMID: 20382572, DOI: 10.1016/j.jpain.2009.10.017.

Heins A, Homel P, Safdar B, Todd K. Physician ethnicity predicts successful ED analgesia. Journal Of Pain 2009, 10: s34. DOI: 10.1016/j.jpain.2009.01.145.

Rao V, Safdar B, Parkosewich J, Lee LV, D'Onofrio G, Foody JM. Improvements in Time to Reperfusion. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2009, 8: 38-42. PMID: 19258837, DOI: 10.1097/hpc.0b013e318194e443.

Safdar B, Heins A, Homel P, Miner J, Neighbor M, DeSandre P, Todd KH. Impact of Physician and Patient Gender on Pain Management in the Emergency Department—A Multicenter Study. Pain Medicine 2009, 10: 364-372. PMID: 18992042, DOI: 10.1111/j.1526-4637.2008.00524.x.

Safdar B, Foody J, D'Onofrio G. Depression is a Common Coronary Risk Factor in Women Admitted to an ED Chest Pain Center. Academic Emergency Medicine 2007, 14: s131-s131. DOI: 10.1197/j.aem.2007.03.1069.

Safdar B, Parkosewich J, Freed L, Foody J, Tandon S, Jubanyik K, Lin Z, D’Onofrio G. 375 A Multi-Faceted Community-Based Educational Program Promotes Cardiovascular Health in Women: 5 Year Analysis. Annals Of Emergency Medicine 2006, 48: 112-113. DOI: 10.1016/j.annemergmed.2006.07.841.

Safdar B, Choiniere M, Crandall C, Ducharme J, Fosnocht D, Homel P, Tanabe P, Todd K. 405 Impact of Patient Gender on Pain Management Practices in the Emergency Department: A Multi-Center Study. Annals Of Emergency Medicine 2006, 48: 121. DOI: 10.1016/j.annemergmed.2006.07.874.

Safdar B, Degutis L, Landry K et al. (2006). Prospective Randomized Controlled Trial comparing Efficacy and Adverse events of Intravenous Ketorolac and Parenteral morphine alone and in combination in the treatment of acute renal colic. Annals of Emergency Medicine. 2006; 48(2):173-181.

Safdar B, Cone D, Pham K. S UBCUTANEOUS E PINEPHRINE IN THE P REHOSPITAL S ETTING. Prehospital Emergency Care 2001, 5: 200-207. PMID: 11339733, DOI: 10.1080/10903120190940137.

Shah B, Safdar B, Virani S, Nawaz Z, Saeed S, Gilani A. The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channels. Vascular Pharmacology 1997, 29: 251-255. PMID: 9251908, DOI: 10.1016/s0306-3623(96)00413-2.