Olanzapine Trial

Olanzapine (ow-lan-zuh-peen) Trial

The purpose of this research study is to determine whether taking an olanzapine pill before surgery will impact your quality of recovery and/or help prevent nausea at home during the first 2 days after leaving the hospital.
If you participate in the study, you will take a pill that is either olanzapine 5 milligrams or a placebo.
If you choose to participate in this research your responsibilities will include taking the study medication in the preoperative room prior to going to the operating room and completing 3 surveys via email; one before surgery, one on the first day after surgery, and one on the second day after surgery. Each survey takes approximately 5-6 minutes to complete.

For more information about this study, including how to volunteer, contact:

Tom Gugel, RN

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

Trial Purpose and Description

Olanzapine (ow-lan-zuh-peen) Trial

The purpose of this research study is to determine whether taking an olanzapine pill before surgery will impact your quality of recovery and/or help prevent nausea at home during the first 2 days after leaving the hospital.
If you participate in the study, you will take a pill that is either olanzapine 5 milligrams or a placebo.
If you choose to participate in this research your responsibilities will include taking the study medication in the preoperative room prior to going to the operating room and completing 3 surveys via email; one before surgery, one on the first day after surgery, and one on the second day after surgery. Each survey takes approximately 5-6 minutes to complete.

Female patients aged 18-50 undergoing ambulatory surgery with general anesthesia;
Access to a smart device or computer with internet connection and an email address.