Tardive Dyskinesia Study

Has a doctor told you that you have or may have Tardive Dyskinesia (TD)?

If you are between the ages of 26 and 84, have been told by a doctor that you have or may have Tardive Dyskinesia (TD), and you have never been treated for this condition you may be eligible to participate in a free and confidential research study investigating psychological adjustment to TD.

If you enroll, you will meet with a neurologist who will evaluate you for TD and with a psychiatrist who will ask you several questions about your psychological adjustment to this condition.

You will be compensated up to $200.00 for your participation.

In order to be eligible for inclusion in the study, an individual must meet all of the following criteria:

(1) Provision of signed and dated informed consent form.

(2) Stated willingness to comply with all study procedures and availability for the duration of the

study

(3) Age: 26-84

(4) Sex: Both males and females will be included

(5) Presumptive diagnosis of dopamine receptor-blocker induced tardive dyskinesia according to

the DSM-5 criteria: “involuntary athetoid or choreiform movements lasting at least a few weeks,

developing in association with the use of a neuroleptic medication for at least a few months, and

persisting beyond 4-8 weeks”

(6) Demoralization score of 10 or higher on the DS-II

Any individual who meets any of the following criteria will be excluded from participation in this study:

(1) Patients with unstable psychiatric status defined as having a total score on BPRS of

50 or higher

(2) Patients who have suicidal or homicidal ideation, intent, or plan or viewed as having a

significant risk of suicidal or violent behavior.

(3) Patients with cognitive impairment as defined by a score of 24 or less on the MMSE

(4) Patients with current diagnosis of alcohol or substance use disorder made according

to DSM-5 criteria

(5) Patients with clinically significant unstable medical condition defined as follows: a comorbid

abnormal movement disorder more prominent than tardive dyskinesia (e.g., parkinsonism, akathisia,

truncal dystonia), a score of greater than 2 on two or more items of the Simpson-Angus Scale, or a

history of neuroleptic malignant syndrome.

(6) Patients previously treated with Valbenazine or any other medication specifically indicated for

tardive dyskinesia

(7) People tested positive for Coronavirus Covid-19

(8) People with impaired decision-making capacity

(9) Institutionalized individuals

(10) Prisoners

(11) Parolees