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T1D RELAY

  • Study HIC#:2000025525
  • Last Updated:09/04/2024

TrialNet is studying the use of rituximab-pvvr and abatacept, one after the other, to learn if using both treatments extends insulin production in people newly diagnosed with type 1 diabetes (T1D).

Previous studies with similar treatments showed people can make more insulin for a longer period of time while receiving either of the treatments. T1D RELAY will study if two treatments consecutively performs better than rituximab-pvvr alone. Researchers will test if those who are also treated with abatacept have better C-peptide levels over time.

  • Age8 years and older
  • GenderBoth

Contact Us

For more information about this study, including how to volunteer, contact:

Marcia DeSousa at The Yale Pediatric Diabetes Program

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

Eligibility Criteria

This study is enrolling children and adults who are:

  • Age 8-45
  • Newly diagnosed with T1D (in past 3 months)

AND have:

  • 1 or more diabetes-related autoantibodies
  • C-peptide detectable during a mixed-meal tolerance test (MMTT)

Principal Investigator

Sub-Investigators

For more information about this study, including how to volunteer, contact:

Marcia DeSousa at The Yale Pediatric Diabetes Program