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Phase I-II

A Phase 1/2a, Open-label, Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BMS-986507 (BL-B01D1) Combinations in Adult Participants With Advanced Solid Tumors

  • Study HIC#:2000038785
  • Last Updated:03/13/2025

The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adult participants with advanced solid tumors.

    Contact Us

    For more information about this study, including how to volunteer, contact:

    Ingrid Palma

    Help Us Discover!

    You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

    Eligibility Criteria

    Inclusion Criteria

    • Participants must have at least one measurable lesion per response evaluation criteria in solid tumors.
    • Participants must have an Eastern Cooperative Oncology Group Performance Status of 0 or 1.
    • Participants must have a life expectancy of at least 3 months at the time of the first dose.

    Exclusion Criteria

    • Participants must not have any mixed Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC) histology.
    • Participants must not have any untreated symptomatic central nervous system (CNS) metastases.
    • Participants must not have a history of serious recurrent infections.
    • Participants must not have a history of severe heart disease.
    • Other protocol-defined Inclusion/Exclusion criteria apply.

    Principal Investigator

    Sub-Investigators

    For more information about this study, including how to volunteer, contact: