X-Linked Agammaglobulinemia (XLA)
Definition
X-linked agammaglobulinemia (XLA) is a rare genetic immunodeficiency disorder characterized by a severe reduction or absence of immunoglobulins, which are essential proteins for the immune system to fight infections. This condition primarily affects males and results in recurrent bacterial infections, increased susceptibility to viruses, and a higher risk of developing autoimmune disorders.