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ALL DEFINITIONS

Marfan Syndrome

Definition

Marfan syndrome is a genetic disorder that affects the body's connective tissue, which provides support and structure to various organs and tissues. It is caused by a mutation in the FBN1 gene, leading to abnormalities in the production of fibrillin-1 protein. This disorder can affect multiple systems, including the skeletal, cardiovascular, and ocular systems, and may result in a variety of symptoms and complications.